Safety, pharmacokinetics and pharmacodynamics of multiple oral doses of apixaban, a factor Xa inhibitor, in healthy subjects

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Safety, pharmacokinetics and pharmacodynamics of multiple oral doses of apixaban, a factor Xa inhibitor, in healthy subjects is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/BCP.12106
P932PMC publication ID3853536
P698PubMed publication ID23451769
P5875ResearchGate publication ID235772931

P2093author name stringZhigang Yu
Sunil Nepal
Charles Frost
Wonkyung Byon
Jessie Wang
Yu Chen Barrett
Frank Lacreta
Andrew Shenker
Rebecca A Boyd
Alan Schuster
Rogelio Mosqueda-Garcia
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Apixaban, an oral direct factor Xa inhibitor, inhibits human clot-bound factor Xa activity in vitro.Q50357077
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Factor Xa--a promising target for drug developmentQ77826627
Clinical laboratory measurement of direct factor Xa inhibitors: anti-Xa assay is preferable to prothrombin time assayQ82070566
Apixaban inhibition of factor Xa: Microscopic rate constants and inhibition mechanism in purified protein systems and in human plasmaQ82961588
Evaluation of the anti-factor Xa chromogenic assay for the measurement of rivaroxaban plasma concentrations using calibrators and controlsQ83080848
Effects of the oral, direct factor Xa inhibitor rivaroxaban on commonly used coagulation assaysQ85193723
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
apixabanQ414462
pharmacodynamicsQ725307
P304page(s)776-786
P577publication date2013-11-01
P1433published inBritish Journal of Clinical PharmacologyQ176044
P1476titleSafety, pharmacokinetics and pharmacodynamics of multiple oral doses of apixaban, a factor Xa inhibitor, in healthy subjects
P478volume76

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cites work (P2860)
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