scholarly article | Q13442814 |
P2093 | author name string | Zhigang Yu | |
Sunil Nepal | |||
Charles Frost | |||
Wonkyung Byon | |||
Jessie Wang | |||
Yu Chen Barrett | |||
Frank Lacreta | |||
Andrew Shenker | |||
Rebecca A Boyd | |||
Alan Schuster | |||
Rogelio Mosqueda-Garcia | |||
P2860 | cites work | Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines | Q24633053 |
Structure-based design of novel potent nonpeptide thrombin inhibitors | Q27638874 | ||
Discovery of 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (apixaban, BMS-562247), a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood [...] | Q27648707 | ||
Razaxaban, a direct factor Xa inhibitor, in combination with aspirin and/or clopidogrel improves low-dose antithrombotic activity without enhancing bleeding liability in rabbits | Q28219397 | ||
Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor | Q28272154 | ||
Apixaban versus warfarin in patients with atrial fibrillation | Q29617563 | ||
Factor Xa or thrombin: is factor Xa a better target? | Q33291055 | ||
Limitations of traditional anticoagulants | Q33362181 | ||
Warfarin therapy: evolving strategies in anticoagulation. | Q33535795 | ||
Apixaban or enoxaparin for thromboprophylaxis after knee replacement | Q34018819 | ||
Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): a randomised double-blind trial | Q34102430 | ||
Apixaban versus enoxaparin for thromboprophylaxis after hip replacement | Q34156023 | ||
Apixaban in patients with atrial fibrillation | Q34163710 | ||
The "HemoQuant" test: a specific and quantitative determination of heme (hemoglobin) in feces and other materials. | Q34265161 | ||
Apixaban, an oral, direct factor Xa inhibitor: single dose safety, pharmacokinetics, pharmacodynamics and food effect in healthy subjects | Q34285711 | ||
Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate | Q34590281 | ||
Assays for measuring rivaroxaban: their suitability and limitations | Q37789142 | ||
In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studies | Q43235385 | ||
A novel prothrombin time assay for assessing the anticoagulant activity of oral factor Xa inhibitors | Q44465978 | ||
Synthetic selective inhibitors of coagulation factor Xa strongly inhibit thrombin generation without affecting initial thrombin forming time necessary for platelet activation in hemostasis | Q44854409 | ||
Arterial antithrombotic and bleeding time effects of apixaban, a direct factor Xa inhibitor, in combination with antiplatelet therapy in rabbits | Q46468984 | ||
Efficacy and safety of the oral direct factor Xa inhibitor apixaban for symptomatic deep vein thrombosis. The Botticelli DVT dose-ranging study | Q46550059 | ||
Apixaban, an oral, direct and highly selective factor Xa inhibitor: in vitro, antithrombotic and antihemostatic studies | Q46722053 | ||
Apixaban, an oral direct factor Xa inhibitor, inhibits human clot-bound factor Xa activity in vitro. | Q50357077 | ||
General derivation of the equation for time to reach a certain fraction of steady state. | Q52434488 | ||
The efficacy and safety of apixaban, an oral, direct factor Xa inhibitor, as thromboprophylaxis in patients following total knee replacement. | Q53229008 | ||
Nonpeptide factor Xa inhibitors: I. Studies with SF303 and SK549, a new class of potent antithrombotics | Q73289567 | ||
Thrombotic events during oral anticoagulant treatment: results of the inception-cohort, prospective, collaborative ISCOAT study: ISCOAT study group (Italian Study on Complications of Oral Anticoagulant Therapy) | Q74019320 | ||
Factor Xa--a promising target for drug development | Q77826627 | ||
Clinical laboratory measurement of direct factor Xa inhibitors: anti-Xa assay is preferable to prothrombin time assay | Q82070566 | ||
Apixaban inhibition of factor Xa: Microscopic rate constants and inhibition mechanism in purified protein systems and in human plasma | Q82961588 | ||
Evaluation of the anti-factor Xa chromogenic assay for the measurement of rivaroxaban plasma concentrations using calibrators and controls | Q83080848 | ||
Effects of the oral, direct factor Xa inhibitor rivaroxaban on commonly used coagulation assays | Q85193723 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | pharmacokinetics | Q323936 |
apixaban | Q414462 | ||
pharmacodynamics | Q725307 | ||
P304 | page(s) | 776-786 | |
P577 | publication date | 2013-11-01 | |
P1433 | published in | British Journal of Clinical Pharmacology | Q176044 |
P1476 | title | Safety, pharmacokinetics and pharmacodynamics of multiple oral doses of apixaban, a factor Xa inhibitor, in healthy subjects | |
P478 | volume | 76 |
Q54965803 | A Case of a Reversible Neurologic Adverse Reaction to Apixaban Confirmed by Re-Challenge. |
Q40090376 | A Systems Pharmacology Model for Predicting Effects of Factor Xa Inhibitors in Healthy Subjects: Assessment of Pharmacokinetics and Binding Kinetics |
Q34531991 | A randomized direct comparison of the pharmacokinetics and pharmacodynamics of apixaban and rivaroxaban |
Q50794115 | Apixaban Pharmacokinetics at Steady State in Hemodialysis Patients. |
Q36836396 | Apixaban Reduces Hospitalizations in Patients With Venous Thromboembolism: An Analysis of the Apixaban for the Initial Management of Pulmonary Embolism and Deep-Vein Thrombosis as First-Line Therapy (AMPLIFY) Trial |
Q26780328 | Apixaban and oral implications |
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Q90103174 | Global thromboelastometry in patients receiving direct oral anticoagulants: the RO-DOA study |
Q28079697 | Implications of apixaban for dental treatments |
Q51739901 | Initial Apixaban Dosing in Patients with Atrial Fibrillation. |
Q38205947 | Interpretation of coagulation test results under direct oral anticoagulants |
Q38956699 | Laboratory Assessment of the Anticoagulant Activity of Direct Oral Anticoagulants: A Systematic Review |
Q34206252 | Laboratory measurement of the anticoagulant activity of the non-vitamin K oral anticoagulants. |
Q39266311 | Laboratory measurement of the direct oral anticoagulants: Indications and impact on management in clinical practice |
Q28257188 | Liver injury with novel oral anticoagulants: assessing post-marketing reports in the US Food and Drug Administration adverse event reporting system |
Q26766303 | Management of Venous Thromboembolism: Recent Advances in Oral Anticoagulation Therapy |
Q38953781 | Measurement and reversal of the direct oral anticoagulants |
Q40744632 | Measurement of dabigatran, rivaroxaban and apixaban in samples of plasma, serum and urine, under real life conditions. An international study. |
Q35154142 | Measurement of non-VKA oral anticoagulants versus classic ones: the appropriate use of hemostasis assays. |
Q45865979 | Measurement of non-coumarin anticoagulants and their effects on tests of Haemostasis: Guidance from the British Committee for Standards in Haematology |
Q34086522 | Measurement of rivaroxaban and apixaban in serum samples of patients |
Q93092143 | Mechanistic Basis for the Differential Effects of Rivaroxaban and Apixaban on Global Tests of Coagulation |
Q34413003 | Model-based exposure-response analysis of apixaban to quantify bleeding risk in special populations of subjects undergoing orthopedic surgery |
Q88670340 | Model-based meta-analysis to evaluate optimal doses of direct oral factor Xa inhibitors in atrial fibrillation patients |
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Q38826151 | Overview of direct oral anticoagulant therapy reversal |
Q38386660 | Pharmacodynamic profile and drug interactions with non-vitamin K antagonist oral anticoagulants: implications for patients with atrial fibrillation |
Q38777127 | Pharmacodynamics, pharmacokinetics and clinical efficacy of apixaban in the treatment of thrombosis |
Q48952027 | Pharmacokinetics, pharmacodynamics, and safety of apixaban in subjects with end-stage renal disease on hemodialysis. |
Q28078967 | Pharmacology of anticoagulants used in the treatment of venous thromboembolism |
Q64977733 | Population Pharmacokinetics of Apixaban in Subjects With Nonvalvular Atrial Fibrillation. |
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