Dimethyl celecoxib sensitizes gastric cancer cells to ABT-737 via AIF nuclear translocation

scientific article published on 04 July 2016

Dimethyl celecoxib sensitizes gastric cancer cells to ABT-737 via AIF nuclear translocation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/JCMM.12913
P932PMC publication ID5082400
P698PubMed publication ID27374973

P2093author name stringBo Zhang
Dan Zhang
Mimi Wang
Linling Wang
Youyou Yan
Nengming Lin
Yangling Li
Jianmei Zeng
P2860cites workThe Dietary Flavonoid Fisetin Causes Cell Cycle Arrest, Caspase-Dependent Apoptosis, and Enhanced Cytotoxicity of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells.Q55032232
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Inhibition mechanism of the intracellular transporter Ca2+-pump from sarco-endoplasmic reticulum by the antitumor agent dimethyl-celecoxibQ28540515
α7 Nicotinic receptor activation reduces β-amyloid-induced apoptosis by inhibiting caspase-independent death through phosphatidylinositol 3-kinase signalingQ34212626
Multitarget inhibition of drug-resistant multiple myeloma cell lines by dimethyl-celecoxib (DMC), a non-COX-2 inhibitory analog of celecoxibQ34445827
Increase of cyclooxygenase-2 inhibition with celecoxib combined with 5-FU enhances tumor cell apoptosis and antitumor efficacy in a subcutaneous implantation tumor model of human colon cancerQ34561552
Celecoxib analogs that lack COX-2 inhibitory function: preclinical development of novel anticancer drugsQ34743086
Di(2-ethylhexyl) phthalate-induced apoptosis in rat INS-1 cells is dependent on activation of endoplasmic reticulum stress and suppression of antioxidant protectionQ35206511
Role of p38 MAPK in enhanced human cancer cells killing by the combination of aspirin and ABT-737.Q35531406
Inhibition of Mcl-1 with the pan-Bcl-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemiaQ35859229
Pharmacological and Protein Profiling Suggests Venetoclax (ABT-199) as Optimal Partner with Ibrutinib in Chronic Lymphocytic LeukemiaQ35958056
Myeloid cell leukemia-1 is an important apoptotic survival factor in triple-negative breast cancerQ36751571
Benefit of adjuvant chemotherapy for resectable gastric cancer: a meta-analysisQ37742318
Review article: the epidemiology and prevention of gastric cancerQ38218870
2,5-Dimethyl-celecoxib inhibits cell cycle progression and induces apoptosis in human leukemia cellsQ38838732
Identification of miRNomes in human stomach and gastric carcinoma reveals miR-133b/a-3p as therapeutic target for gastric cancerQ38843492
Development of 2-aryl substituted quinazolin-4(3H)-one, pyrido[4,3-d]pyrimidin-4(3H)-one and pyrido[2,3-d]pyrimidin-4(3H)-one derivatives as microsomal prostaglandin E(2) synthase-1 inhibitorsQ38953025
Celecoxib exerts antitumor effects in canine mammary tumor cells via COX‑2‑independent mechanismsQ39062494
Platinum compounds sensitize ovarian carcinoma cells to ABT-737 by modulation of the Mcl-1/Noxa axisQ39205781
The tumor suppressor microRNA-29c is downregulated and restored by celecoxib in human gastric cancer cells.Q39273352
ABT-737 synergizes with arsenic trioxide to induce apoptosis of gastric carcinoma cells in vitro and in vivoQ39280369
Suppression of myeloid cell leukemia-1 (Mcl-1) enhances chemotherapy-associated apoptosis in gastric cancer cellsQ39360253
PI3K inhibition potentiates Bcl-2-dependent apoptosis in renal carcinoma cellsQ39437267
Enhanced killing of chemo-resistant breast cancer cells via controlled aggravation of ER stressQ39864165
Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxibQ40017297
Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancerQ42003270
The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma.Q42968961
In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins.Q43142228
Antiangiogenic activities of 2,5-dimethyl-celecoxib on the tumor vasculatureQ43144727
Antitumor effect of a selective COX-2 inhibitor, celecoxib, may be attributed to angiogenesis inhibition through modulating the PTEN/PI3K/Akt/HIF-1 pathway in an H₂₂ murine hepatocarcinoma modelQ45308080
Hypoxia-induced p38 MAPK activation reduces Mcl-1 expression and facilitates sensitivity towards BH3 mimetics in chronic lymphocytic leukemia.Q51685717
P433issue11
P304page(s)2148-2159
P577publication date2016-07-04
P1433published inJournal of Cellular and Molecular MedicineQ1524063
P1476titleDimethyl celecoxib sensitizes gastric cancer cells to ABT-737 via AIF nuclear translocation
P478volume20

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cites work (P2860)
Q47268493Combination of arsenic trioxide and Dasatinib: a new strategy to treat Philadelphia chromosome-positive acute lymphoblastic leukaemia
Q64113606The Ibr-7 derivative of ibrutinib exhibits enhanced cytotoxicity against non-small cell lung cancer cells via targeting of mTORC1/S6 signaling

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