The archipelago tumor suppressor gene limits rb/e2f-regulated apoptosis in developing Drosophila tissues

scientific article published on 03 September 2009

The archipelago tumor suppressor gene limits rb/e2f-regulated apoptosis in developing Drosophila tissues is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CUB.2009.07.068
P932PMC publication ID2755617
P698PubMed publication ID19733076
P5875ResearchGate publication ID26792147

P50authorMaxim V FrolovQ98569211
P2093author name stringKenneth H Moberg
Brandon N Nicolay
M Melissa Gilbert
Sarah C Nicholson
P2860cites worksprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airwaysQ24336220
Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell linesQ28188140
The transcription factor E2F is required for S phase during Drosophila embryogenesisQ28292608
Sibling rivalry in the E2F familyQ29615056
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiationQ29616127
The p53 pathway: positive and negative feedback loopsQ29617535
The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes.Q33845842
Molecular cloning of sequences from wingless, a segment polarity gene in Drosophila: the spatial distribution of a transcript in embryos.Q33929225
The argos gene encodes a diffusible factor that regulates cell fate decisions in the Drosophila eye.Q34439501
ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP.Q35193528
Regulation of imaginal disc growth by tumor-suppressor genes in DrosophilaQ36548698
Signal integration during development: mechanisms of EGFR and Notch pathway function and cross-talkQ36648414
Hippo signaling in organ size controlQ36793377
Regulation of apoptosis of rbf mutant cells during Drosophila developmentQ37081384
Regulation of Drosophila embryonic tracheogenesis by dVHL and hypoxia.Q37208300
Conserved functions of the pRB and E2F familiesQ37249375
Genetic control of programmed cell death in DrosophilaQ38468332
A gradient of epidermal growth factor receptor signaling determines the sensitivity of rbf1 mutant cells to E2F-dependent apoptosisQ38508876
Retinoblastoma family 2 is required in vivo for the tissue-specific repression of dE2F2 target genesQ38513343
FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppressionQ39904718
Drosophila p53 binds a damage response element at the reaper locusQ41731875
The Drosophila F-box protein Archipelago controls levels of the Trachealess transcription factor in the embryonic tracheal systemQ42913052
Wingless eliminates ommatidia from the edge of the developing eye through activation of apoptosis.Q44884941
A role for wingless in an early pupal cell death event that contributes to patterning the Drosophila eye.Q45129152
Role of the proneural gene, atonal, in formation of Drosophila chordotonal organs and photoreceptorsQ45936203
Atonal is the proneural gene for Drosophila photoreceptors.Q45994865
Effect on eye development of dominant mutations in Drosophila homologue of the EGF receptor.Q46020365
Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor geneQ46284220
Extracellular signals responsible for spatially regulated proliferation in the differentiating Drosophila eye.Q46421007
Ras promotes cell survival in Drosophila by downregulating hid expressionQ47070193
Germ line and soma cooperate during oogenesis to establish the dorsoventral pattern of egg shell and embryo in Drosophila melanogasterQ47070232
Drosophila myc regulates organ size by inducing cell competitionQ47071644
Control of cell proliferation in the Drosophila eye by Notch signaling.Q47072084
dMyc transforms cells into super-competitorsQ47072112
The Drosophila F box protein archipelago regulates dMyc protein levels in vivoQ47072740
The Drosophila ribosomal protein L14-encoding gene, identified by a novel Minute mutation in a dense cluster of previously undescribed genes in cytogenetic region 66D.Q48048857
Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs.Q51113909
Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7.Q51952187
The contribution of E2F-regulated transcription to Drosophila PCNA gene function.Q52110249
Suppression of the rbf null mutants by a de2f1 allele that lacks transactivation domain.Q52172305
Evolution of proneural atonal expression during distinct regulatory phases in the developing Drosophila eye.Q52199556
The beginning of pattern formation in the Drosophila compound eye: the morphogenetic furrow and the second mitotic waveQ52445408
Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation.Q52543351
Drosophila myc regulates cellular growth during development.Q52573250
Regulation of cell number by MAPK-dependent control of apoptosis: a mechanism for trophic survival signaling.Q52594202
Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing.Q52664437
Cooperative tumorigenic effects of germline mutations in Rb and p53Q72781894
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectDrosophilaQ312154
P304page(s)1503-1510
P577publication date2009-09-03
P1433published inCurrent BiologyQ1144851
P1476titleThe archipelago tumor suppressor gene limits rb/e2f-regulated apoptosis in developing Drosophila tissues
P478volume19

Reverse relations

cites work (P2860)
Q41889504A screen for conditional growth suppressor genes identifies the Drosophila homolog of HD-PTP as a regulator of the oncoprotein Yorkie
Q36444155Competition among gene regulatory networks imposes order within the eye-antennal disc of Drosophila
Q42097572E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila
Q34422783Notch-dependent expression of the archipelago ubiquitin ligase subunit in the Drosophila eye.
Q36889941Regulation of Yorkie activity in Drosophila imaginal discs by the Hedgehog receptor gene patched
Q35141270Role of Drosophila retinoblastoma protein instability element in cell growth and proliferation
Q34390559S phase-coupled E2f1 destruction ensures homeostasis in proliferating tissues
Q34298342The dREAM/Myb-MuvB complex and Grim are key regulators of the programmed death of neural precursor cells at the Drosophila posterior wing margin
Q34011624The gang of four gene regulates growth and patterning of the developing Drosophila eye.
Q33680727Tuberous Sclerosis Complex 1 Regulates dE2F1 Expression during Development and Cooperates with RBF1 to Control Proliferation and Survival
Q34209588mir-11 limits the proapoptotic function of its host gene, dE2f1

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