BK Polyomavirus and the Transplanted Kidney: Immunopathology and Therapeutic Approaches

scientific article published on 07 July 2016

BK Polyomavirus and the Transplanted Kidney: Immunopathology and Therapeutic Approaches is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1097/TP.0000000000001333
P932PMC publication ID5084638
P698PubMed publication ID27391196

P50authorCaroline LamarcheQ64514998
Jean-Sébastien DelisleQ73833054
Marie-Josée HébertQ40276349
P2093author name stringJulie Orio
Lee Anne Tibbles
Lynne Senécal
Suzon Collette
Édith Renoult
P2860cites workPolyomaviruses and disease: is there more to know than viremia and viruria?Q28081350
New human papovavirus (B.K.) isolated from urine after renal transplantationQ28236639
Prevalence of polyomavirus BK and JC infection and replication in 400 healthy blood donorsQ28244625
Cellular and molecular immune profiles in renal transplant recipients after conversion from tacrolimus to sirolimusQ30301338
Polyomavirus BK replication in de novo kidney transplant patients receiving tacrolimus or cyclosporine: a prospective, randomized, multicenter studyQ30422449
Lack of BK virus DNA sequences in most transitional-cell carcinomas of the bladderQ33267775
An OPTN analysis of national registry data on treatment of BK virus allograft nephropathy in the United StatesQ33427765
Urinary proinflammatory cytokine response in renal transplant recipients with polyomavirus BK viruriaQ33515560
Human polyomavirus (BK) infection and ureteric stenosis in renal allograft recipientsQ33606896
Leflunomide inhibition of BK virus replication in renal tubular epithelial cellsQ33614540
Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipientsQ33634455
Urinary-cell mRNA profile and acute cellular rejection in kidney allograftsQ34037420
Polyomavirus BK infection in pediatric kidney-allograft recipients: a single-center analysis of incidence, risk factors, and novel therapeutic approachesQ44419275
Reactivation of BK polyomavirus in patients with multiple sclerosis receiving natalizumab therapyQ44498475
BK virus-specific antibodies and BKV DNA in renal transplant recipients with BKV nephritisQ44571746
HLA mismatching increases the risk of BK virus nephropathy in renal transplant recipientsQ45058863
BK virus-associated nephropathy in renal allograft recipients: rescue therapy by sirolimus-based immunosuppressionQ45103464
Polyomavirus nephropathy in pediatric kidney transplant recipientsQ45171047
Incidence of BK with tacrolimus versus cyclosporine and impact of preemptive immunosuppression reductionQ45262232
Effect of leflunomide and cidofovir on replication of BK virus in an in vitro culture systemQ45267785
BK Virus Infection After Kidney Transplantation: The Data Are Mounting for a Personalized ApproachQ45339039
Banff 2013 meeting report: inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesionsQ45342440
The genetic predisposition of natural killer cell to BK virus-associated nephropathy in renal transplant patientsQ45352216
BK virus-specific T cells for use in cellular therapy show specificity to multiple antigens and polyfunctional cytokine responsesQ45362434
BK virus-specific immunity kinetics: a predictor of recovery from polyomavirus BK-associated nephropathy.Q45364259
Does reduction in immunosuppression in viremic patients prevent BK virus nephropathy in de novo renal transplant recipients? A prospective studyQ45395619
Functional characterization of BK virus-specific CD4+ T cells with cytotoxic potential in seropositive adultsQ45399744
Donor origin of BK virus in renal transplantation and role of HLA C7 in susceptibility to sustained BK viremiaQ45427404
BK Polyoma Virus Allograft Nephropathy: Ultrastructural Features from Viral Cell Entry to LysisQ45710937
Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1 in urineQ45730363
BK virus regulatory region rearrangements in brain and cerebrospinal fluid from a leukemia patient with tubulointerstitial nephritis and meningoencephalitisQ45732749
Identification of archetype and rearranged forms of BK virus in leukocytes from healthy individualsQ45745122
Human polyoma virus-associated interstitial nephritis in the allograft kidneyQ45751593
BK and JC viruses in human immunodeficiency virus type 1-infected persons: prevalence, excretion, viremia, and viral regulatory regionsQ45778896
Renal failure due to BK virus infection in an immunodeficient childQ45785284
Human polyomavirus in pregnancy. A model for the study of defence mechanisms to virus reactivationQ45797965
The role of BK virus in acute respiratory tract disease and the presence of BKV DNA in tonsilsQ45799462
The effects of renal transplantation on circulating dendritic cells.Q46419669
Successful treatment of BK viremia using reduction in immunosuppression without antiviral therapyQ46687452
Dendritic cell deficiency in the blood of kidney transplant patients on long-term immunosuppression: results of a prospective matched-cohort studyQ46816114
Reduced exposure to calcineurin inhibitors in renal transplantationQ46840533
BKV and SV40 infection of human kidney tubular epithelial cells in vitroQ47354606
Population-based study of antibody to the human polyomaviruses BKV and JCV and the simian polyomavirus SV40.Q47763052
BK and JC viruses in patients with systemic lupus erythematosus: prevalent and persistent BK viruria, sequence stability of the viral regulatory regions, and nondetectable viremiaQ47959065
Infection of human polyomaviruses JC and BK in peripheral blood leukocytes from immunocompetent individualsQ48086009
Evidence of human polyomavirus BK and JC infection in normal brain tissueQ48416768
Isolation of papovavirus from brain tumor and urine of a patient with Wiskott-Aldrich syndromeQ48512511
Pathology of resolving polyomavirus-associated nephropathy.Q51873284
Differential effects of mycophenolate mofetil and cyclosporine A on peripheral blood and cord blood natural killer cells activated with interleukin-2.Q54200595
A human papovavirus (B.K.), biological properties and seroepidemiology.Q54250082
Dendritic cell deficiency associated with development of BK viremia and nephropathy in renal transplant recipients.Q54446958
Tubulo-Interstitial Nephritis Associated with Polyomavirus (BK Type) InfectionQ67287983
Association of BK viruria with hemorrhagic cystitis in recipients of bone marrow transplantsQ70142893
Polyomavirus persistence in lymphocytes: prevalence in lymphocytes from blood donors and healthy personnel of a blood transfusion centreQ74016225
Bladder carcinoma in a transplant recipient: evidence to implicate the BK human polyomavirus as a causal transforming agentQ74493975
The induction of neoplasms with a substance released from mouse tumors by tissue cultureQ74512300
Polyomavirus BK non-coding control region rearrangements in health and diseaseQ80538891
Polyomavirus polymerase chain reaction as a surrogate marker of polyomavirus-associated nephropathyQ80798773
Polyomavirus BK-specific immunity after kidney transplantationQ80903029
The effects of renal transplantation on peripheral blood dendritic cellsQ81175772
Prospective monitoring of polyomavirus BK replication and impact of pre-emptive intervention in pediatric kidney recipientsQ81379957
HLA susceptibility to BKV infectionQ82515115
Antigen-specific T cell responses to BK polyomavirus antigens identify functional anti-viral immunity and may help to guide immunosuppression following renal transplantationQ84357905
Interobserver agreement for Polyomavirus nephropathy grading in renal allografts using the working proposal from the 10th Banff Conference on Allograft PathologyQ84512637
Prevalence in England of antibody to human polyomavirus (B.k.).Q84953205
Reactivation of polyoma virus in kidneys of persistently infected mice during pregnancyQ34092581
A filterable agent, recovered from Ak leukemic extracts, causing salivary gland carcinomas in C3H miceQ34232505
Activity of broad-spectrum T cells as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT.Q34273968
Agnoprotein of mammalian polyomavirusesQ34283583
Validation of noninvasive diagnosis of BK virus nephropathy and identification of prognostic biomarkersQ34337472
Insight into the role of mTOR and metabolism in T cells reveals new potential approaches to preventing graft rejectionQ34437449
Role of a nuclear localization signal on the minor capsid proteins VP2 and VP3 in BKPyV nuclear entry.Q34451457
Interplay of cellular and humoral immune responses against BK virus in kidney transplant recipients with polyomavirus nephropathyQ34545686
Oncogenic potentials of the human polyomavirus regulatory proteinsQ34625941
Polyomavirus BK neutralizing activity in human immunoglobulin preparationsQ34786755
Polyomavirus BK.Q35548648
Stimulation of BK virus DNA replication by NFI family transcription factorsQ35826187
The Banff 2009 Working Proposal for polyomavirus nephropathy: a critical evaluation of its utility as a determinant of clinical outcomeQ35870126
The unexpected effect of cyclosporin A on CD56+CD16- and CD56+CD16+ natural killer cell subpopulationsQ35989434
Polyomavirus-associated nephropathy in renal transplantation: interdisciplinary analyses and recommendationsQ36136619
BK virus: opportunity makes a pathogenQ36188861
Sequence Variation in Amplification Target Genes and Standards Influences Interlaboratory Comparison of BK Virus DNA Load Measurement.Q36297604
A serological investigation of BK virus and JC virus infections in recipients of renal allograftsQ36342486
High Prevalence of Antibodies to BK Virus, an SV40-related Papovavirus, in Residents of MarylandQ36520893
Polyomavirus BK with rearranged noncoding control region emerge in vivo in renal transplant patients and increase viral replication and cytopathologyQ36537931
Correlates of quantitative measurement of BK polyomavirus (BKV) DNA with clinical course of BKV infection in renal transplant patientsQ36598800
A steroid hormone response unit in the late leader of the noncoding control region of the human polyomavirus BK confers enhanced host cell permissivity.Q36632077
Adult mouse kidneys become permissive to acute polyomavirus infection and reactivate persistent infections in response to cellular damage and regenerationQ36643498
Polyoma virus infection and urothelial carcinoma of the bladder following renal transplantationQ36965036
Immune evasion of natural killer cells by virusesQ37060710
Detection of BK virus DNA in nasopharyngeal aspirates from children with respiratory infections but not in saliva from immunodeficient and immunocompetent adult patientsQ37086788
BK virus antibody titers and intensity of infections after renal transplantationQ37239525
HLA-A2, HLA-B44 and HLA-DR15 are associated with lower risk of BK viremiaQ37349698
The Polyomaviridae: Contributions of virus structure to our understanding of virus receptors and infectious entryQ37373700
Efficacy of levofloxacin in the treatment of BK viremia: a multicenter, double-blinded, randomized, placebo-controlled trialQ37621540
Noninvasive prognostication of polyomavirus BK virus-associated nephropathyQ37631149
BK-virus and the impact of pre-emptive immunosuppression reduction: 5-year resultsQ37670279
Treatment of polyomavirus infection in kidney transplant recipients: a systematic review.Q37678906
Review on the relationship between human polyomaviruses-associated tumors and host immune systemQ38001435
BK virus-associated urinary bladder carcinoma in transplant recipients: report of 2 cases, review of the literature, and proposed pathogenetic model.Q38073911
Cellular immunotherapy for patients with reactivation of JC and BK polyomaviruses after transplantationQ38220648
ERAD and how viruses exploit it.Q38234935
Recent advances in cytomegalovirus: an update on pharmacologic and cellular therapiesQ38276074
Levofloxacin for BK virus prophylaxis following kidney transplantation: a randomized clinical trialQ38420919
Detection of human polyomaviruses and papillomaviruses in prostatic tissue reveals the prostate as a habitat for multiple viral infections.Q38454485
BK Virus Nephropathy in Kidney Transplantation: An Approach Proposal and Update on Risk Factors, Diagnosis, and TreatmentQ38570451
Inhibition of BK virus replication in human kidney cells by BK virus large tumor antigen-specific shRNA delivered by JC virus-like particlesQ39035911
Fluoroquinolones inhibit human polyomavirus BK (BKV) replication in primary human kidney cellsQ39499064
An identical miRNA of the human JC and BK polyoma viruses targets the stress-induced ligand ULBP3 to escape immune eliminationQ39592344
Anti-BK Virus Mechanisms of Sirolimus and Leflunomide Alone and in Combination: Toward a New Therapy for BK Virus InfectionQ39631502
KDIGO clinical practice guideline for the care of kidney transplant recipientsQ39936865
Inhibition of Simian virus 40 large T antigen helicase activity by fluoroquinolones.Q40132770
HLA type-independent method to monitor polyoma BK virus-specific CD4 and CD8 T-cell immunityQ40351825
Dendritic cells pulsed with polyomavirus BK antigen induce ex vivo polyoma BK virus-specific cytotoxic T-cell lines in seropositive healthy individuals and renal transplant recipients.Q40613236
Risk Factors for BK Polyoma Virus Treatment and Association of Treatment With Kidney Transplant Failure: Insights From a Paired Kidney AnalysisQ40745543
Intragraft Blood Dendritic Cell Antigen-1-Positive Myeloid Dendritic Cells Increase during BK Polyomavirus-Associated NephropathyQ40858336
Optimizing JC and BK polyomavirus IgG testing for seroepidemiology and patient counselingQ41000259
The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms.Q41103097
Efficacy of intravenous immunoglobulin in the treatment of persistent BK viremia and BK virus nephropathy in renal transplant recipientsQ41432471
Clinical Utility of Urinary Cytology to Detect BK Viral NephropathyQ41432805
Polyomavirus-induced interstitial nephritis in two renal transplant recipients: case reports and review of the literatureQ41477413
Sp1 sites in the noncoding control region of BK polyomavirus are key regulators of bidirectional viral early and late gene expressionQ41544370
Persistence of DNA Sequences of BK Virus and JC Virus in Normal Human Tissues and in Diseased TissuesQ41555932
The risk of polyomavirus BK-associated hemorrhagic cystitis after allogeneic hematopoietic SCT is associated with myeloablative conditioning, CMV viremia and severe acute GVHD.Q42200730
BK polyomavirus-specific cellular immune responses are age-dependent and strongly correlate with phases of virus replicationQ42225033
High burden of BK virus-associated hemorrhagic cystitis in patients undergoing allogeneic hematopoietic stem cell transplantationQ42230071
Genomics of BK viremia in kidney transplant recipientsQ42250844
BK polyomavirus in solid organ transplantationQ42272314
Treatment of BK viremia after renal transplantation: are fluoroquinolones a false dawn?Q42420884
Disseminated BK type polyomavirus infection in an AIDS patient associated with central nervous system diseaseQ42754947
Reducing immunosuppression preserves allograft function in presumptive and definitive polyomavirus-associated nephropathy.Q42790826
Renal Failure Five Years After Lung Transplantation Due to Polyomavirus BK‐Associated NephropathyQ42907634
BK virus large T and VP-1 expression in infected human renal allograftsQ43184361
Expansion of cytomegalovirus pp65 and IE-1 specific cytotoxic T lymphocytes for cytomegalovirus-specific immunotherapy following allogeneic stem cell transplantationQ43225933
Inhibition of polyomavirus BK-specific T-Cell responses by immunosuppressive drugsQ43236446
Polyomavirus in kidney and kidney-pancreas transplantation: a defined protocol for immunosuppression reduction and histologic monitoringQ43536824
Polyoma virus infection after renal transplantation. Use of immunostaining as a guide to diagnosisQ43605141
Donor and recipient BKV-specific IgG antibody and posttransplantation BKV infection: a prospective single-center studyQ43660039
BK-VP3 as a new target of cellular immunity in BK virus infectionQ43702582
Polyoma viral infection in renal transplantation: the role of immunosuppressive therapyQ43782396
Limited efficacy of immunosuppressive drugs on CD8+ T cell-mediated and natural killer cell-mediated lysis of human renal tubular epithelial cellsQ43900811
Sirolimus versus tacrolimus in kidney transplant recipients receiving mycophenolate mofetil and steroids: focus on acute rejection, patient and graft survivalQ44019892
Clinical course of polyoma virus nephropathy in 67 renal transplant patientsQ44077395
Risk factors for BK virus infection in the era of therapeutic drug monitoringQ44077791
Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipientsQ44104230
Molecular evaluation of BK polyomavirus nephropathyQ44313013
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivativesQ6937225
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectvirusQ808
BK virusQ582873
kidney transplantationQ740909
tumor virus infectionsQ69561737
P304page(s)2276-2287
P577publication date2016-07-07
2016-11-01
P1433published inTransplantationQ15730500
P1476titleBK Polyomavirus and the Transplanted Kidney: Immunopathology and Therapeutic Approaches
P478volume100

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cites work (P2860)
Q92531711Acute Rejection in Kidney Transplantation and Early Beginning of Tacrolimus
Q47557746Aryl hydrocarbon receptor expression by macrophages and lymphocytes within infiltrates in BK polyomavirus associated nephropathy
Q37747582BK viruria and viremia in children with systemic lupus erythematosus
Q90734448Comparison of the effects of standard vs low-dose prolonged-release tacrolimus with or without ACEi/ARB on the histology and function of renal allografts
Q59359682High-Dose Intravenous Immunoglobulin Treatment of Polyomavirus Nephropathy Developing After T Cell-Mediated Rejection Treatment: A Case Report
Q97535447Neurological immunotherapy in the era of COVID-19 - looking for consensus in the literature
Q92068281Non-invasive urinary sediment double-immunostaining predicts BK polyomavirus associated-nephropathy in kidney transplant recipients
Q99583669Pathological characteristics of BK polyomavirus-associated nephropathy with glomerular involvement
Q90176540The immunophenotyping of different stages of BK virus allograft nephropathy
Q64109430The therapeutic effect of switching from tacrolimus to low-dose cyclosporine A in renal transplant recipients with BK virus nephropathy
Q40039485Treatment of Theiler's virus-induced demyelinating disease with teriflunomide.
Q47602423Treatment of human polyomavirus-7-associated rash and pruritus with topical cidofovir in a lung transplant patient: Case report and literature review.
Q40115230Urothelial cell carcinoma after BK polyomavirus infection in kidney transplant recipients: A cohort study of veterans.

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