Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo.

scientific article published on 21 June 2009

Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1053/J.GASTRO.2009.06.046
P932PMC publication ID2757464
P698PubMed publication ID19549525
P5875ResearchGate publication ID26313990

P50authorAlexander DietrichQ48892276
Veit FlockerziQ56384346
Alexander V ZholosQ57064384
Marc FreichelQ90178430
Lutz BirnbaumerQ92613192
P2093author name stringMichael X Zhu
Stephan E Philipp
Thomas Aberle
Volodymyr V Tsvilovskyy
P2860cites workDirect activation of human TRPC6 and TRPC3 channels by diacylglycerolQ22001504
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patchesQ22337395
Contribution of transient receptor potential channels to the control of GABA release from dendritesQ28510991
Control of intestinal motility by the Ca(v)1.2 L-type calcium channel in miceQ28587703
Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1Q28587996
An introduction to TRP channelsQ29615753
TRP channelsQ29616673
The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channelQ30979449
Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- miceQ31929609
Excitation-contraction coupling in gastrointestinal and other smooth musclesQ33547215
Increased vascular smooth muscle contractility in TRPC6-/- miceQ33924920
Invited review: mechanisms of calcium handling in smooth musclesQ34339355
Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchangeQ34586634
TRPC4 and TRPC5: receptor-operated Ca2+-permeable nonselective cation channelsQ35135489
Nonselective cation channels activated by the stimulation of muscarinic receptors in mammalian gastric smooth muscleQ35719111
Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP.Q35844666
Muscarinic receptor-activated cationic channels in murine ileal myocytes.Q36052445
Specific detection and semi-quantitative analysis of TRPC4 protein expression by antibodiesQ36167773
G-protein-gated TRP-like cationic channel activated by muscarinic receptors: effect of potential on single-channel gatingQ36447244
Mechanisms of action of transmitters and other substances on smooth muscleQ39259380
Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphateQ40019222
N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity.Q40635186
TRPC1 and TRPC5 form a novel cation channel in mammalian brain.Q40812989
Receptor-mediated regulation of the nonselective cation channels TRPC4 and TRPC5.Q40876055
Receptor signaling mechanisms underlying muscarinic agonist-evoked contraction in guinea-pig ileal longitudinal smooth muscleQ41952936
Muscarinic agonist potencies at three different effector systems linked to the M(2) or M(3) receptor in longitudinal smooth muscle of guinea-pig small intestineQ42066429
Muscarinic receptor subtypes controlling the cationic current in guinea-pig ileal smooth muscle.Q42152886
Phospholipase C, but not InsP3 or DAG, -dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells.Q43263139
Effects of G-protein-specific antibodies and G beta gamma subunits on the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cellsQ43263360
Acetylcholine activates nonselective cation channels in guinea pig ileum through a G proteinQ44596820
Phospholipase C involvement in activation of the muscarinic receptor-operated cationic current in Guinea pig ileal smooth muscle cellsQ44950726
Effects of isoflurane on gastrointestinal motility after brief exposure in ratsQ46425378
Intracellular calcium ions modulate acetylcholine-induced inward current in guinea-pig ileumQ46784148
Role of Ca2+ mobilization in muscarinic receptor-mediated membrane depolarization in guinea pig ileal smooth muscle cellsQ46844113
TRPC4 is an essential component of the nonselective cation channel activated by muscarinic stimulation in mouse visceral smooth muscle cellsQ46887982
GTP-binding protein involvement in membrane currents evoked by carbachol and histamine in guinea-pig ileal muscleQ46987777
Characterization of muscarinic receptor-mediated cationic currents in longitudinal smooth muscle cells of mouse small intestineQ46990838
Physiological features of visceral smooth muscle cells, with special reference to receptors and ion channelsQ47801970
The depolarizing action of acetylcholine or carbachol in intestinal smooth muscle.Q54037370
Store-operated Ca2+ entry in platelets occurs independently of transient receptor potential (TRP) C1Q57987885
Fluoroaluminates activate transducin-GDP by mimicking the gamma-phosphate of GTP in its binding siteQ69846903
Vasoactive intestinal polypeptide appears to be one of the mediators in misoprostol-enhanced small intestinal transit in ratsQ73269043
M2 receptor activation of nonselective cation channels in smooth muscle cells: calcium and Gi/G(o) requirementsQ73644533
Differential expression and alternative splicing of TRP channel genes in smooth musclesQ73711726
Muscarinic receptors controlling the carbachol-activated nonselective cationic current in guinea pig gastric smooth muscle cellsQ73942809
Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeabilityQ74452970
Carbachol-induced oscillations in membrane potential and [Ca2+]i in guinea-pig ileal smooth muscle cellsQ77097721
Three distinct muscarinic signalling pathways for cationic channel activation in mouse gut smooth muscle cellsQ80226392
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)1415-1424
P577publication date2009-06-21
P1433published inGastroenterologyQ4039279
P1476titleDeletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo
P478volume137

Reverse relations

cites work (P2860)
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