Trk inhibition reduces cell proliferation and potentiates the effects of chemotherapeutic agents in Ewing sarcoma.

scientific article published on 26 April 2016

Trk inhibition reduces cell proliferation and potentiates the effects of chemotherapeutic agents in Ewing sarcoma. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.8992
P932PMC publication ID5085195
P698PubMed publication ID27145455

P50authorRafael RoeslerQ77616037
P2093author name stringAlgemir Lunardi Brunetto
Michel Pinheiro Dos Santos
Caroline Brunetto de Farias
Lauro José Gregianin
André Tesainer Brunetto
Bárbara Kunzler Souza
Ricardo Gehrke Becker
Tiago Elias Heinen
Patrícia Luciana da Costa Lopez
Rafael Pereira Dos Santos
Amanda da Rocha
Luís Fernando da Rosa Rivero
Marco Aurélio Silva Filho
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Ewing's sarcomaQ82884131
K252a is a selective inhibitor of the tyrosine protein kinase activity of the trk family of oncogenes and neurotrophin receptorsQ34537348
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Trk inhibitor attenuates the BDNF/TrkB-induced protection of neuroblastoma cells from etoposide in vitro and in vivoQ36214947
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NTRK1 rearrangement in colorectal cancer patients: evidence for actionable target using patient-derived tumor cell lineQ36629492
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Sarcomas gone bad: what to do about recurrent Ewing sarcomaQ37890995
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High levels of class III β-tubulin expression are associated with aggressive tumor features in breast cancerQ38719315
TrkB inhibition by GNF-4256 slows growth and enhances chemotherapeutic efficacy in neuroblastoma xenograftsQ38940598
In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma.Q39045925
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AZ64 inhibits TrkB and enhances the efficacy of chemotherapy and local radiation in neuroblastoma xenograftsQ39343234
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P4510describes a project that usesImageJQ1659584
ImageQuantQ112270642
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectchemotherapyQ974135
P304page(s)34860-34880
P577publication date2016-06-01
P1433published inOncotargetQ1573155
P1476titleTrk inhibition reduces cell proliferation and potentiates the effects of chemotherapeutic agents in Ewing sarcoma
P478volume7

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cites work (P2860)
Q91811059Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma
Q51334063Combined Treatments with a Retinoid Receptor Agonist and Epigenetic Modulators in Human Neuroblastoma Cells.
Q41912578Dual inhibition of BDNF/TrkB and autophagy: a promising therapeutic approach for colorectal cancer
Q54974651Gene expression changes associated with chemotherapy resistance in Ewing sarcoma cells.
Q50201584Neurotrophin Trk Receptors: New Targets for Cancer Therapy
Q48110212Targeting Histone Deacetylase Activity to Arrest Cell Growth and Promote Neural Differentiation in Ewing Sarcoma.
Q61456294Targeting the BDNF/TrkB pathway for the treatment of tumors
Q54941876Targeting tyrosine receptor kinase B in gliomas.
Q38666650Uncovering the role of brain-derived neurotrophic factor/tyrosine kinase receptor B signaling in head and neck malignancies.

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