Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells.

scientific article published on October 2016

Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells. is …
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scholarly articleQ13442814

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P356DOI10.1242/DEV.139360
P932PMC publication ID5087640
P698PubMed publication ID27802135

P50authorMinoru S.H. KoQ58478823
Tomohiko AkiyamaQ88666995
Shigeru B H KoQ88666998
Mayumi OdaQ37369448
P2093author name stringYuhki Nakatake
Miyako Murakami
Atsumi Soma
Miki Sakota
Nana Chikazawa-Nohtomi
Saeko Sato
Shunichi Wakabayashi
P2860cites workGenomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domainsQ21092474
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EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotencyQ24645960
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Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program.Q50493794
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Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitinationQ34673352
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Runx2/Cbfa1: A Multifunctional Regulator of Bone FormationQ35552258
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Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4Q35849667
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Human ES- and iPS-derived myogenic progenitors restore DYSTROPHIN and improve contractility upon transplantation in dystrophic mice.Q35947481
Histone demethylase UTX and chromatin remodeler BRM bind directly to CBP and modulate acetylation of histone H3 lysine 27.Q36023292
The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongationQ36070586
Transient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cellsQ36131205
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cellsQ36140488
Histone demethylase KDM6B promotes epithelial-mesenchymal transitionQ36492862
The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functionsQ36824171
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Jmjd3 inhibits reprogramming by upregulating expression of INK4a/Arf and targeting PHF20 for ubiquitinationQ37091343
Epigenomic analysis of multilineage differentiation of human embryonic stem cellsQ37205415
Organogenesis and development of the liverQ37693447
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PRC2 mediated H3K27 methylations in cellular identity and cancer.Q38615439
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Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells.Q38771932
Histone H3K27me3 demethylases KDM6A and KDM6B modulate definitive endoderm differentiation from human ESCs by regulating WNT signaling pathway.Q39294157
Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cellsQ39840959
The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation.Q40752964
Myoblasts derived from normal hESCs and dystrophic hiPSCs efficiently fuse with existing muscle fibers following transplantationQ41136531
Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3Q41305645
Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells.Q41514993
Turning on myogenin in muscle: a paradigm for understanding mechanisms of tissue-specific gene expression.Q42234367
Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy.Q42819955
Activation of neuronal gene expression by the JMJD3 demethylase is required for postnatal and adult brain neurogenesis.Q42949497
Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cellsQ46678698
Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cellsQ46879255
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue20
P407language of work or nameEnglishQ1860
P921main subjectpluripotencyQ1894941
P1104number of pages12
P304page(s)3674-3685
P577publication date2016-10-01
P1433published inDevelopmentQ3025404
P1476titleTransient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells
P478volume143