Cytotoxic T cell response against the chimeric ETV6-AML1 protein in childhood acute lymphoblastic leukemia

scientific article published on July 1998

Cytotoxic T cell response against the chimeric ETV6-AML1 protein in childhood acute lymphoblastic leukemia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI3126
P932PMC publication ID508905
P698PubMed publication ID9664088

P2093author name stringGrandchamp B
Peuchmaur M
Lemonnier F
Vilmer E
Garcia F
Duval M
Langlade-Demoyen P
Yotnda P
P2860cites workIdentification of programmed cell death in situ via specific labeling of nuclear DNA fragmentationQ24642901
A monoclonal antibody reactive with a 15-kDa cytoplasmic granule-associated protein defines a subpopulation of CD8+ T lymphocytes.Q34147970
Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocationQ34340175
Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopesQ35093159
Theiler's virus and Mengo virus induce cross-reactive cytotoxic T lymphocytes restricted to the same immunodominant VP2 epitope in C57BL/6 miceQ35888374
Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytesQ36363449
Definition of a minimal optimal cytotoxic T-cell epitope within the hepatitis B virus nucleocapsid proteinQ36687045
TEL-AML1 fusion RNA as a new target to detect minimal residual disease in pediatric B-cell precursor acute lymphoblastic leukemia.Q36807501
An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I proteinQ37644137
High frequency of t(12;21) in childhood B-lineage acute lymphoblastic leukemia.Q38288856
Cancer immunotherapy using interleukin-2 and interleukin-2-activated lymphocytesQ39733329
Analysis of ETV6 and ETV6-AML1 proteins in acute lymphoblastic leukaemiaQ41101992
BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytesQ41371291
Constitutive expression of c-myc does not relieve cAMP-mediated growth arrest in human lymphoid Reh cellsQ41522106
The 12;21 translocation involving TEL and deletion of the other TEL allele: two frequently associated alterations found in childhood acute lymphoblastic leukemiaQ47335313
Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC moleculesQ55042699
The involvement of transforming growth factor beta in the impaired antitumor T-cell response at the gut-associated lymphoid tissue (GALT)Q70786892
TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosisQ71020950
Efficient binding to the MHC class I K(d) molecule of synthetic peptides in which the anchoring position 2 does not fit the consensus motifQ71130344
A simple assay for detection of peptides promoting the assembly of HLA class I moleculesQ72285904
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
cytotoxicityQ246181
P304page(s)455-462
P577publication date1998-07-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleCytotoxic T cell response against the chimeric ETV6-AML1 protein in childhood acute lymphoblastic leukemia
P478volume102

Reverse relations

cites work (P2860)
Q40608665A gene expressed exclusively in acute B lymphoblastic leukemias
Q36813562A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas.
Q47608571A structure-based approach for prediction of MHC-binding peptides
Q28184349AML1 interconnected pathways of leukemogenesis
Q35293385Absence of leukaemic fusion gene transcripts in preterm infants exposed to diagnostic x rays
Q34875170Adoptive cellular therapy: a therapeutic reality?
Q52953925Altered patterns of T cell cytokine production induced by relapsed pre-B ALL cells.
Q36240201Antigen-specific cellular immunotherapy of leukemia.
Q36662079Augmentation of anti-tumor immunity by adoptive T-cell transfer after allogeneic hematopoietic stem cell transplantation
Q72995666Augmentation of immune response by altered peptide ligands of the antigenic peptide in a human CD4+ T-cell clone reacting to TEL/AML1 fusion protein
Q24806130BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1
Q78306894CD40 ligand-stimulated B cell precursor leukemic cells elicit interferon-gamma production by autologous bone marrow T cells in childhood acute lymphoblastic leukemia
Q74169459Cytotoxic T-lymphocyte responses elicited to Wilms' tumor gene WT1 product by DNA vaccination
Q34417562Exploiting genetic alterations to design novel therapies for cancer
Q34451905Gene therapy for paediatric leukaemia
Q46171835Histone deacetylase inhibition improves differentiation of dendritic cells from leukemic blasts of patients with TEL/AML1-positive acute lymphoblastic leukemia
Q41533232Human Tumor Antigens and Cancer Immunotherapy
Q47133741Identification and Characterization of Neoantigens As Well As Respective Immune Responses in Cancer Patients
Q34155839Identification of a human telomerase reverse transcriptase peptide of low affinity for HLA A2.1 that induces cytotoxic T lymphocytes and mediates lysis of tumor cells.
Q40750584Identification of a novel WT1-derived peptide which induces human leucocyte antigen-A24-restricted anti-leukaemia cytotoxic T lymphocytes
Q36369960Identification of a novel major histocompatibility complex class II-restricted tumor antigen resulting from a chromosomal rearrangement recognized by CD4(+) T cells
Q35169125Identification of human tumor antigens recognized by T-cells and their use for immunotherapy
Q46050360Immunity and protection, the unfolding of a tale
Q90215738Immunogenic neoantigens derived from gene fusions stimulate T cell responses
Q33731552Immunotherapy in acute leukemia
Q35971029Immunotherapy targets in pediatric cancer
Q37851050Insights into the processing of MHC class I ligands gained from the study of human tumor epitopes
Q35994924Interferon alpha and T-cell responses in chronic myeloid leukemia
Q34214817Leukemia vaccines
Q78581871Leukemia-associated fusion proteins, dek-can and bcr-abl, represent immunogenic HLA-DR-restricted epitopes recognized by fusion peptide-specific CD4+ T lymphocytes
Q34060270MLL-rearranged B lymphoblastic leukemias selectively express the immunoregulatory carbohydrate-binding protein galectin-1.
Q36891310Mobilizing the low-avidity T cell repertoire to kill tumors
Q89965697Neoantigens in Hematologic Malignancies
Q92539066Neoantigens in Hematological Malignancies-Ultimate Targets for Immunotherapy?
Q37248354Novel molecular and cellular therapeutic targets in acute lymphoblastic leukemia and lymphoproliferative disease
Q57941422Parameters involved in the recognition of fresh human leukemic blasts by tumor-specific cytolytic T cell clones: a model study
Q40661469Pilot trial of tumor-specific peptide vaccination and continuous infusion interleukin-2 in patients with recurrent Ewing sarcoma and alveolar rhabdomyosarcoma: an inter-institute NIH study
Q34258082Prospect for immunotherapy of acute lymphoblastic leukemia
Q34608658T-cell therapy of leukemia.
Q33750862T-cell-based therapies for malignancy and infection in childhood
Q34108113Targeting pediatric malignancies for T cell-mediated immune responses
Q36745749Telomerase immunity from bench to bedside: round one.
Q36042528Telomerase reverse transcriptase as target for anti-tumor T cell responses in humans
Q92538890The Genomic Landscape of Antigenic Targets for T Cell-Based Leukemia Immunotherapy
Q99548643The Origin and Immune Recognition of Tumor-Specific Antigens
Q35000726The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research
Q59094157Transplantation for Childhood Acute Lymphoblastic Leukemia
Q35214398Tumor-associated antigens: from discovery to immunity
Q34399765Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy
Q64378949[Contribution of antineoplastic biotherapy in the treatment of leukemia in children]

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