Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells

scientific article published on 09 September 2013

Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/MC.22050
P932PMC publication ID3859703
P698PubMed publication ID24019090

P50authorShivendra V SinghQ91346531
Eun-Ryeong HahmQ91713662
P2093author name stringJoomin Lee
P2860cites workTargeting Mcl-1 for the therapy of cancerQ27011870
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Withaferin A, a Cytotoxic Steroid from Vassobia breviflora, Induces Apoptosis in Human Head and Neck Squamous Cell CarcinomaQ33667199
Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen speciesQ33997100
Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesisQ34091296
Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylationQ34182050
Withaferin A induces p53-dependent apoptosis by repression of HPV oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cellsQ34209940
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D,L-sulforaphane-induced apoptosis in human breast cancer cells is regulated by the adapter protein p66ShcQ35659007
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Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cellsQ36328445
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Protective effect of Withaferin-A on tumour formation in 7,12-dimethylbenz[a]anthracene induced oral carcinogenesis in hamsters.Q46076946
Withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through mitochondrial death cascade.Q46261561
Neuroprotective effects of Withania somnifera on 6-hydroxydopamine induced Parkinsonism in ratsQ46496568
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Effect of withaferin a on Ehrlich ascites tumor cells. II. Target tumor cell destructionin vivoby immune activationQ67245649
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectbreast cancerQ128581
apoptotic processQ14599311
P304page(s)907-916
P577publication date2013-09-09
P1433published inMolecular CarcinogenesisQ15724597
P1476titleRole of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells
P478volume53