| scholarly article | Q13442814 |
| P50 | author | Rosalind Jenkins | Q71169765 |
| P2093 | author name string | B Kevin Park | |
| Hartmut Jaeschke | |||
| Daniel J Antoine | |||
| Benjamin L Woolbright | |||
| Mary Lynn Bajt | |||
| P2860 | cites work | Circulating microRNAs, potential biomarkers for drug-induced liver injury | Q24656209 |
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| The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis | Q33732343 | ||
| Chronic cholestatic diseases | Q33870255 | ||
| Variant forms of cholestatic diseases involving small bile ducts in adults | Q33918825 | ||
| Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting | Q33961753 | ||
| Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity | Q34024427 | ||
| Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium | Q34109467 | ||
| miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. | Q34592976 | ||
| Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis | Q34760897 | ||
| Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury | Q34909256 | ||
| Bile acid regulation of hepatic physiology: IV. Bile acids and death receptors | Q35102867 | ||
| An updated review on drug-induced cholestasis: mechanisms and investigation of physicochemical properties and pharmacokinetic parameters | Q35206374 | ||
| Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury | Q35546843 | ||
| Effect of bile duct ligation on bile acid composition in mouse serum and liver | Q35687185 | ||
| Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes | Q35824326 | ||
| The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation | Q35858082 | ||
| Apoptosis: a mechanism of acute and chronic liver injury | Q36160716 | ||
| Novel insight into mechanisms of cholestatic liver injury | Q36285749 | ||
| Mechanisms of Liver Injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions | Q36474595 | ||
| Contrasting responses of Kupffer cells and inflammatory mononuclear phagocytes to biliary obstruction in a mouse model of cholestatic liver injury | Q36517945 | ||
| Fas receptor-deficient lpr mice are protected against acetaminophen hepatotoxicity due to higher glutathione synthesis and enhanced detoxification of oxidant stress | Q36988910 | ||
| Bile-acid-induced cell injury and protection | Q37157813 | ||
| The BH3-only protein bid does not mediate death-receptor-induced liver injury in obstructive cholestasis | Q37316494 | ||
| Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital | Q37346819 | ||
| Bile salts and cholestasis. | Q37740584 | ||
| Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts | Q37825662 | ||
| Early growth response factor-1 is critical for cholestatic liver injury | Q38511428 | ||
| Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent | Q39914977 | ||
| Diet Restriction Inhibits Apoptosis and HMGB1 Oxidation and Promotes Inflammatory Cell Recruitment during Acetaminophen Hepatotoxicity | Q41963390 | ||
| Early detection of paracetamol toxicity using circulating liver microRNA and markers of cell necrosis | Q42545817 | ||
| High-mobility group box-1 protein and keratin-18, circulating serum proteins informative of acetaminophen-induced necrosis and apoptosis in vivo | Q43270651 | ||
| Bid antisense attenuates bile acid-induced apoptosis and cholestatic liver injury. | Q43803789 | ||
| Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis? | Q43994104 | ||
| Prevention of bile acid-induced apoptosis by betaine in rat liver | Q44151751 | ||
| Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles | Q44165186 | ||
| Oncotic necrosis and caspase-dependent apoptosis during galactosamine-induced liver injury in rats | Q44494746 | ||
| Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation | Q44520881 | ||
| Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice | Q44527586 | ||
| Functional importance of ICAM-1 in the mechanism of neutrophil-induced liver injury in bile duct-ligated mice | Q44620832 | ||
| Tauroursodeoxycholic acid protects rat hepatocytes from bile acid-induced apoptosis via activation of survival pathways | Q44927719 | ||
| Reduced oncotic necrosis in Fas receptor-deficient C57BL/6J-lpr mice after bile duct ligation | Q45070063 | ||
| Oncosis represents the main type of cell death in mouse models of cholestasis | Q45264412 | ||
| Characterization of time-related changes after experimental bile duct ligation | Q46807443 | ||
| Activation of caspase 3 (CPP32)-like proteases is essential for TNF-alpha-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model. | Q50131662 | ||
| Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas. | Q50517174 | ||
| Circulating microRNAs as potential markers of human drug-induced liver injury | Q60609564 | ||
| Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release | Q72412472 | ||
| Parenchymal cell apoptosis as a signal for sinusoidal sequestration and transendothelial migration of neutrophils in murine models of endotoxin and Fas-antibody-induced liver injury | Q77220681 | ||
| Overexpression of Bcl-2 in hepatocytes protects against injury but does not attenuate fibrosis in a mouse model of chronic cholestatic liver disease | Q85057882 | ||
| P433 | issue | 3 | |
| P921 | main subject | inflammation | Q101991 |
| apoptotic process | Q14599311 | ||
| biomarker | Q864574 | ||
| P304 | page(s) | 524-531 | |
| P577 | publication date | 2013-10-03 | |
| P1433 | published in | Toxicology and Applied Pharmacology | Q2446974 |
| P1476 | title | Plasma biomarkers of liver injury and inflammation demonstrate a lack of apoptosis during obstructive cholestasis in mice | |
| P478 | volume | 273 |
| Q53223990 | Activation of Flucloxacillin-Specific CD8+ T-Cells With the Potential to Promote Hepatocyte Cytotoxicity in a Mouse Model. |
| Q57106957 | Advances in drug-induced cholestasis: Clinical perspectives, potential mechanisms and in vitro systems |
| Q52669418 | Assessment of serum bile acid profiles as biomarkers of liver injury and liver disease in humans. |
| Q35181443 | Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis |
| Q42318815 | Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response |
| Q34422178 | Biomarkers distinguish apoptotic and necrotic cell death during hepatic ischemia/reperfusion injury in mice. |
| Q41247526 | Bone Fracture Enhances Trauma Brain Injury |
| Q55000878 | Cell Death and Prognosis of Mortality in Alcoholic Hepatitis Patients Using Plasma Keratin-18. |
| Q36614256 | Critical Factors in the Assessment of Cholestatic Liver Injury In Vitro |
| Q36454762 | Critical review of resveratrol in xenobiotic-induced hepatotoxicity. |
| Q57478272 | Danger-Associated Molecular Patterns (DAMPs): Molecular Triggers for Sterile Inflammation in the Liver |
| Q38740599 | Dioscin Protects ANIT-Induced Intrahepatic Cholestasis Through Regulating Transporters, Apoptosis and Oxidative Stress |
| Q53828360 | Evaluation of plasma microRNA-122, high-mobility group box 1 and keratin-18 concentrations to stratify acute gallstone disease: a pilot observational cohort study in an emergency general surgery unit. |
| Q34606009 | Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patients |
| Q88160215 | In vitro prediction of drug-induced cholestatic liver injury: a challenge for the toxicologist |
| Q41050095 | Induction of chronic cholestasis without liver cirrhosis - Creation of an animal model |
| Q93112129 | Inflammation and Cell Death During Cholestasis: The Evolving Role of Bile Acids |
| Q89178743 | Is Keratin-18 only a Marker of Cell Death in Acute-On-Chronic Liver Failure? |
| Q33754301 | Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice |
| Q37623548 | Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice |
| Q39367594 | Mechanisms of bile acid mediated inflammation in the liver |
| Q38212434 | Mechanistic biomarkers in acetaminophen-induced hepatotoxicity and acute liver failure: from preclinical models to patients |
| Q49862111 | MiR-122 and other microRNAs as potential circulating biomarkers of drug-induced liver injury |
| Q35750622 | MicroRNAs as Signaling Mediators and Biomarkers of Drug- and Chemical-Induced Liver Injury. |
| Q92377698 | Mitochondrial dysfunction as a mechanism of drug-induced hepatotoxicity: current understanding and future perspectives |
| Q92377619 | Novel circulating- and imaging-based biomarkers to enhance the mechanistic understanding of human drug-induced liver injury |
| Q35479252 | Oral administration of oleanolic acid, isolated from Swertia mussotii Franch, attenuates liver injury, inflammation, and cholestasis in bile duct-ligated rats |
| Q37419341 | Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice |
| Q35847494 | Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice |
| Q38753644 | Recent advances in biomarkers and therapeutic interventions for hepatic drug safety - false dawn or new horizon? |
| Q33746984 | Serum miRNA signature diagnoses and discriminates murine colitis subtypes and predicts ulcerative colitis in humans. |
| Q51029705 | Sortilin 1 Loss-of-Function Protects Against Cholestatic Liver Injury by Attenuating Hepatic Bile Acid Accumulation in Bile Duct Ligated Mice. |
| Q26799490 | Sterile inflammation in acute liver injury: myth or mystery? |
| Q38626534 | Studies on the mechanisms of bile acid initiated hepatic inflammation in cholestatic liver injury |
| Q35932294 | Swertianlarin, an Herbal Agent Derived from Swertia mussotii Franch, Attenuates Liver Injury, Inflammation, and Cholestasis in Common Bile Duct-Ligated Rats |
| Q33847610 | The Impact of Sterile Inflammation in Acute Liver Injury |
| Q36960966 | Therapeutic targets for cholestatic liver injury |
| Q26800213 | Xenobiotic and Endobiotic Mediated Interactions Between the Cytochrome P450 System and the Inflammatory Response in the Liver |
| Q53099936 | miRNA profiling for diagnosis, prognosis and stratification of cancer treatment in cholangiocarcinoma. |
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