Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition

scientific article published on 20 October 2008

Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/CIRCULATIONAHA.108.791533
P932PMC publication ID2763350
P698PubMed publication ID18936326
P5875ResearchGate publication ID23399718

P50authorBradford G. HillQ37381688
Roberto BolliQ56166630
Detlef Obal, M.D., Ph.D., D.E.S.A.Q64948848
P2093author name stringMatthew B West
Yu-Ting Xuan
Aruni Bhatnagar
Daniel J Conklin
Sumanth D Prabhu
Jay L Zweier
Murugesan Velayutham
Rachel J Keith
Gregg Rokosh
Yiru Guo
Jürgen Schrader
Detlef Obal
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Gene dosage-dependent effects of cardiac-specific overexpression of the A3 adenosine receptorQ30453517
The late phase of ischemic preconditioning is abrogated by targeted disruption of the inducible NO synthase geneQ30454405
Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart.Q31552541
The late phase of preconditioningQ33926118
Preconditioning the Myocardium: From Cellular Physiology to Clinical CardiologyQ33972677
Role of endothelium-derived nitric oxide in the regulation of cardiac oxygen metabolism: implications in health and diseaseQ34101082
Does nitric oxide modulate mitochondrial energy generation and apoptosis?Q34127186
Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of researchQ34439279
The mitochondrial death/life regulator in apoptosis and necrosisQ34465435
Role of the mitochondrial permeability transition in myocardial diseaseQ35204734
Primary and secondary signaling pathways in early preconditioning that converge on the mitochondria to produce cardioprotectionQ35625497
Mitochondrial permeability transition pore opening during myocardial reperfusion--a target for cardioprotectionQ35666876
The role of oxidants and free radicals in reperfusion injuryQ36437576
Demonstration of an early and a late phase of ischemic preconditioning in miceQ36982103
Nitric oxide donors induce late preconditioning against myocardial stunning and infarction in conscious rabbits via an antioxidant-sensitive mechanismQ36982154
Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide.Q38357891
Structural changes in myocardium during acute ischemia.Q39946383
Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusionQ41977320
Cardiac-specific overexpression of inducible nitric oxide synthase does not result in severe cardiac dysfunctionQ43851357
Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?Q44088292
Ischaemic preconditioning inhibits opening of mitochondrial permeability transition pores in the reperfused rat heartQ44401253
Preconditioning delays Ca2+-induced mitochondrial permeability transitionQ44734187
Opening of the mitochondrial permeability transition pore induces reactive oxygen species production at the level of the respiratory chain complex I.Q44764287
Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protectionQ44832208
Preconditioning improves postischemic mitochondrial function and diminishes oxidation of mitochondrial proteinsQ44926081
Specific inhibition of the mitochondrial permeability transition prevents lethal reperfusion injuryQ45255900
Activation of mitochondrial ATP-dependent potassium channels by nitric oxide.Q53918295
Nitric Oxide Inhibits Caspase-3 byS-Nitrosationin VivoQ63303725
Nitric Oxide Inhibition of Lipid Peroxidation: Kinetics of Reaction with Lipid Peroxyl Radicals and Comparison with α-Tocopherol†Q63676968
Measurement of nitric oxide and peroxynitrite generation in the postischemic heart. Evidence for peroxynitrite-mediated reperfusion injuryQ71763431
Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvateQ78020301
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
reperfusion injuryQ1413991
P304page(s)1970-1978
P577publication date2008-10-20
P1433published inCirculationQ578091
P1476titleCardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition
P478volume118

Reverse relations

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