An ancient defense system eliminates unfit cells from developing tissues during cell competition

scientific article published on December 2014

An ancient defense system eliminates unfit cells from developing tissues during cell competition is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1126/SCIENCE.1258236
P932PMC publication ID5095928
P698PubMed publication ID25477468
P5875ResearchGate publication ID269107524

P50authorKonrad BaslerQ21031911
Marc AmoyelQ52814313
P2093author name stringL A Johnston
C Bergantiños
C de la Cova
C Schertel
S N Meyer
P2860cites workThe evolution and origin of animal Toll-like receptor signaling pathway revealed by network-level molecular evolutionary analysesQ27330157
Myc-driven endogenous cell competition in the early mammalian embryoQ28294348
Ribosomal protein L24 defect in belly spot and tail (Bst), a mouse MinuteQ28587678
The Toll-receptor family and control of innate immunityQ33536547
Control of wing size and proportions by Drosophila mycQ33628429
dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cellsQ33707393
Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphologyQ33709552
Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural developmentQ33943141
Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signalingQ34230078
Phylogeny of Toll-like receptor signaling: adapting the innate responseQ34552210
Caspase-mediated processing of the Drosophila NF-kappaB factor RelishQ35022591
Genome Surveyor 2.0: cis-regulatory analysis in DrosophilaQ35075548
The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune responseQ35110457
Caspar, a suppressor of antibacterial immunity in DrosophilaQ35133822
Toll receptor-mediated Drosophila immune response requires Dif, an NF-kappaB factorQ35193354
Steep differences in wingless signaling trigger Myc-independent competitive cell interactionsQ35532153
Toll and IMD pathways synergistically activate an innate immune response in Drosophila melanogasterQ35857132
The unicellular ancestry of animal developmentQ35885254
Soluble factors mediate competitive and cooperative interactions between cells expressing different levels of Drosophila Myc.Q36276873
Activated STAT regulates growth and induces competitive interactions independently of Myc, Yorkie, Wingless and ribosome biogenesisQ36321327
Competitive interactions eliminate unfit embryonic stem cells at the onset of differentiation.Q37022942
Tube Is an IRAK-4 homolog in a Toll pathway adapted for development and immunityQ37211852
Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genesQ37238973
Toll-related receptors and the control of antimicrobial peptide expression in DrosophilaQ37250237
Origins of immunity: Relish, a compound Rel-like gene in the antibacterial defense of DrosophilaQ37337612
Competitive interactions between cells: death, growth, and geographyQ37531604
Dif, a dorsal-related gene that mediates an immune response in Drosophila.Q38314185
Supercompetitor status of Drosophila Myc cells requires p53 as a fitness sensor to reprogram metabolism and promote viabilityQ38563566
Evidence for a Growth-Stabilizing Regulatory Feedback Mechanism between Myc and Yorkie, the Drosophila Homolog of YapQ42023045
The origins of multicellular organismsQ43594390
The genome of the sponge Amphimedon queenslandica provides new perspectives into the origin of Toll-like and interleukin 1 receptor pathways.Q43809640
Immune Activation of NF-κB and JNK Requires Drosophila TAK1Q44757920
Minutes: Mutants of Drosophila autonomously affecting cell division rateQ44889355
Relish, a central factor in the control of humoral but not cellular immunity in DrosophilaQ45007881
The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryoQ46271602
Drosophila myc regulates organ size by inducing cell competitionQ47071644
dMyc transforms cells into super-competitorsQ47072112
Origin of Toll-like receptor-mediated innate immunity.Q47342612
Lactobacillus plantarum promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensingQ48112010
Dorsal, an embryonic polarity gene in Drosophila, is homologous to the vertebrate proto-oncogene, c-relQ48336508
Safeguards for cell cooperation in mouse embryogenesis shown by genome-wide cheater screen.Q50722305
The Dorsal-related immunity factor (Dif) can define the dorsal-ventral axis of polarity in the Drosophila embryo.Q52186630
Drosophila myc regulates cellular growth during development.Q52573250
Drosophila immunity: two paths to NF-kappaB.Q52587765
Cell competition.Q52713623
P4510describes a project that usesImageJQ1659584
P433issue6214
P407language of work or nameEnglishQ1860
P304page(s)1258236
P577publication date2014-12-01
P1433published inScienceQ192864
P1476titleAn ancient defense system eliminates unfit cells from developing tissues during cell competition
P478volume346

Reverse relations

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