Combining Theoretical and Experimental Techniques to Study Murine Heart Transplant Rejection

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Combining Theoretical and Experimental Techniques to Study Murine Heart Transplant Rejection is …
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scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2016.00448
P932PMC publication ID5097940
P698PubMed publication ID27872621

P50authorJulia ArcieroQ55315519
Gerald BrandacherQ64124356
P2093author name stringGiorgio Raimondi
Byoung Chol Oh
Anirudh Arun
Andrew Maturo
P2860cites workInterleukin-10 and the interleukin-10 receptorQ24290912
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Non-self recognition by monocytes initiates allograft rejectionQ30584875
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Mammalian target of rapamycin inhibition and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipientsQ34073891
Innate immunity alone is not sufficient for chronic rejection but predisposes healed allografts to T cell-mediated pathologyQ34121197
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CD4 T cell-mediated cardiac allograft rejection requires donor but not host MHC class II.Q35127578
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Vigorous allograft rejection in the absence of dangerQ73520550
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Cutting edge: CD4+CD25+ alloantigen-specific immunoregulatory cells that can prevent CD8+ T cell-mediated graft rejection: implications for anti-CD154 immunotherapyQ78488897
Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant toleranceQ80358513
CD4 T cell-dependent conditioning of dendritic cells to produce IL-12 results in CD8-mediated graft rejection and avoidance of toleranceQ81767220
BelataceptQ84859618
Organ Transplants: The Costs of SuccessQ47447794
In vivo visualization of cardiac allograft rejection and trafficking passenger leukocytes using bioluminescence imagingQ48945611
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A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation.Q51944707
Natural and induced tolerance in an immune network model.Q52037732
The role of CD8 and CD4 T cells in intestinal allograft rejection: a comparison of monoclonal antibody-treated and knockout mice.Q52533607
Analysis of the B7 costimulatory pathway in allograft rejectionQ56908403
Transplantation tolerance induced by CTLA4-IgQ56909687
Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lgQ56909899
Chemokine receptor‐dependent alloresponsesQ35583497
Estimation of the rate of killing by cytotoxic T lymphocytes in vivoQ35616401
Routes to transplant tolerance versus rejection; the role of cytokines.Q35671669
Visualizing the first 50 hr of the primary immune response to a soluble antigen.Q35882923
Mathematical Modeling of Early Cellular Innate and Adaptive Immune Responses to Ischemia/Reperfusion Injury and Solid Organ AllotransplantationQ36098058
CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.Q36364843
CD4+ but not CD8+ cells are essential for allorejectionQ36367566
Tolerance induction in HLA disparate living donor kidney transplantation by donor stem cell infusion: durable chimerism predicts outcomeQ36492262
Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart.Q36602112
Toward a multiscale model of antigen presentation in immunityQ36762526
Mathematical models of cytotoxic T-lymphocyte killingQ36786522
Simulation and prediction of the adaptive immune response to influenza A virus infectionQ37247935
T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivoQ37308435
Mechanisms Underlying CD4+ Treg Immune Regulation in the Adult: From Experiments to ModelsQ37317297
Lessons and limits of mouse modelsQ37340373
Cell communications in the heart.Q37784108
Lymphodepletion and homeostatic proliferation: implications for transplantationQ37993873
Regulatory immune cells in transplantationQ38013048
The impact of infection and tissue damage in solid-organ transplantationQ38013050
Regulatory T-cell therapy for transplantation: how many cells do we need?Q38025843
Restraint of inflammatory signaling by interdependent strata of negative regulatory pathwaysQ38044665
T-cell co-stimulatory blockade in transplantation: two steps forward one step back!Q38148197
Inflammatory triggers of acute rejection of organ allografts.Q38187172
Regulatory T cells: first steps of clinical application in solid organ transplantationQ38485004
LFA-1 antagonism inhibits early infiltration of endogenous memory CD8 T cells into cardiac allografts and donor-reactive T cell primingQ39101460
Introduction of a Framework for Dynamic Knowledge Representation of the Control Structure of Transplant Immunology: Employing the Power of Abstraction with a Solid Organ Transplant Agent-Based ModelQ40289666
Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival.Q40459668
The use of CD4 and CD8 knockout mice to study the role of T-cell subsets in allotransplant rejectionQ41408659
Endogenous memory CD8 T cells directly mediate cardiac allograft rejectionQ42238758
Characterizing the dynamics of CD4+ T cell priming within a lymph nodeQ42260980
The initial phase of an immune response functions to activate regulatory T cellsQ42571413
Correlation between IL-6 levels and the systemic inflammatory response score: can an IL-6 cutoff predict a SIRS state?Q44100565
Graft produced interleukin-6 functions as a danger signal and promotes rejection after transplantation.Q44639353
Different costimulatory and growth factor requirements for CD4+ and CD8+ T cell-mediated rejectionQ44947130
Different Dynamics of CD4+ and CD8+ T Cell Responses During and After Acute Lymphocytic Choriomeningitis Virus InfectionQ45710912
Adoptive transfer of transplantation tolerance mediated by CD4+CD25+ and CD8+CD28- regulatory T cells induced by anti-donor-specific T-cell vaccinationQ45810452
The allograft defines the type of rejection (acute versus chronic) in the face of an established effector immune responseQ47371063
P407language of work or nameEnglishQ1860
P921main subjectmathematical modelQ486902
P304page(s)448
P577publication date2016-11-07
P1433published inFrontiers in ImmunologyQ27723748
P1476titleCombining Theoretical and Experimental Techniques to Study Murine Heart Transplant Rejection
P478volume7

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Q90342327A case for the reuse and adaptation of mechanistic computational models to study transplant immunologycites workP2860

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