scholarly article | Q13442814 |
P50 | author | George Koob | Q5541413 |
P2093 | author name string | Brendan M Walker | |
P2860 | cites work | Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat | Q28583983 |
Role of GABAB receptor in alcohol dependence: Reducing effect of baclofen on alcohol intake and alcohol motivational properties in rats and amelioration of alcohol withdrawal syndrome and alcohol craving in human alcoholics | Q29395989 | ||
Drug addiction, dysregulation of reward, and allostasis | Q29616741 | ||
Excessive ethanol drinking following a history of dependence: animal model of allostasis | Q33900052 | ||
GABA(B) receptor agonists for the treatment of drug addiction: a review of recent findings | Q34528008 | ||
GABA(A) receptor modulation of the rewarding and aversive effects of ethanol | Q34679246 | ||
Ethanol increases GABAergic transmission at both pre- and postsynaptic sites in rat central amygdala neurons | Q34763227 | ||
The role of GABAA receptors in mediating the effects of alcohol in the central nervous system. | Q35162516 | ||
A role for GABA mechanisms in the motivational effects of alcohol | Q35903158 | ||
Suppression of alcohol delirium tremens by baclofen administration: a case report. | Q40558892 | ||
A physiological role for GABAB receptors and the effects of baclofen in the mammalian central nervous system | Q40929779 | ||
Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: an in vivo microdialysis study | Q41084585 | ||
Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis | Q41680193 | ||
Operant self-administration of sweetened versus unsweetened ethanol: effects on blood alcohol levels | Q41684775 | ||
Effects of baclofen and nitrendipine on ethanol withdrawal responses in the rat. | Q41842832 | ||
Rapid suppression of alcohol withdrawal syndrome by baclofen. | Q43917172 | ||
Long-term ethanol administration methods for rats: advantages of inhalation over intubation or liquid diets | Q44043558 | ||
Baclofen efficacy in reducing alcohol craving and intake: a preliminary double-blind randomized controlled study | Q44129398 | ||
Baclofen suppresses motivation to consume alcohol in rats | Q44386024 | ||
Effect of baclofen on alcohol and sucrose self-administration in rats | Q44490189 | ||
Comparison of the effects of allopregnanolone with direct GABAergic agonists on ethanol self-administration with and without concurrently available sucrose | Q44523845 | ||
The effect of baclofen alone and in combination with naltrexone on ethanol consumption in the rat. | Q45011871 | ||
Increased GABA release in the central amygdala of ethanol-dependent rats. | Q45146982 | ||
Enhanced alcohol self-administration after intermittent versus continuous alcohol vapor exposure | Q45152845 | ||
Ethanol potentiation of GABAergic synaptic transmission may be self-limiting: role of presynaptic GABA(B) receptors. | Q45163153 | ||
GABA antagonist and benzodiazepine partial inverse agonist reduce motivated responding for ethanol | Q46368132 | ||
Baclofen inhibits heroin self-administration behavior and mesolimbic dopamine release | Q48131620 | ||
Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal | Q48320890 | ||
Intra-amygdala muscimol decreases operant ethanol self-administration in dependent rats | Q48903690 | ||
Modulation of A10 dopamine neurons by gamma-aminobutyric acid agonists | Q48988021 | ||
GABAA receptor antagonism in the extended amygdala decreases ethanol self-administration in rats. | Q52206021 | ||
Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats. | Q52260802 | ||
GABAA and GABAB receptor site distribution in the rat central nervous system | Q70180394 | ||
Ethanol inhibition of N-methyl-D-aspartate responses involves presynaptic gamma-aminobutyric acid(B) receptors | Q74016667 | ||
P433 | issue | 1 | |
P304 | page(s) | 11-18 | |
P577 | publication date | 2007-01-01 | |
P1433 | published in | Alcoholism: Clinical and Experimental Research | Q4713331 |
P1476 | title | The gamma-aminobutyric acid-B receptor agonist baclofen attenuates responding for ethanol in ethanol-dependent rats | |
P478 | volume | 31 |
Q59127665 | A Review of the Potential Mechanisms of Action of Baclofen in Alcohol Use Disorder |
Q58090041 | A deeper insight into how GABA-B receptor agonism via baclofen may affect alcohol seeking and consumption: lessons learned from a human laboratory investigation |
Q37255442 | A novel procedure for assessing the effects of drugs on satiation in baboons: effects of memantine and dexfenfluramine |
Q34785056 | A preliminary double-blind, placebo-controlled randomized study of baclofen effects in alcoholic smokers |
Q40195959 | A selective ALDH-2 inhibitor reduces anxiety in rats |
Q33828177 | Acamprosate and naltrexone treatment effects on ethanol and sucrose seeking and intake in ethanol-dependent and nondependent rats |
Q34813687 | Activation of σ-receptors induces binge-like drinking in Sardinian alcohol-preferring rats |
Q37060525 | Acute interaction of baclofen in combination with alcohol in heavy social drinkers |
Q39286561 | Addiction as a BAD, a Behavioral Allocation Disorder. |
Q37315976 | Addiction as a stress surfeit disorder. |
Q37061135 | Addiction is a Reward Deficit and Stress Surfeit Disorder |
Q34162858 | Adolescent binge drinking leads to changes in alcohol drinking, anxiety, and amygdalar corticotropin releasing factor cells in adulthood in male rats |
Q30442446 | Affective cue-induced escalation of alcohol self-administration and increased 22-kHz ultrasonic vocalizations during alcohol withdrawal: role of kappa-opioid receptors |
Q37357479 | Alcohol self-administration acutely stimulates the hypothalamic-pituitary-adrenal axis, but alcohol dependence leads to a dampened neuroendocrine state |
Q38801049 | An Animal Model of Alcohol Dependence to Screen Medications for Treating Alcoholism. |
Q93063740 | Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues |
Q39066739 | Antireward, compulsivity, and addiction: seminal contributions of Dr. Athina Markou to motivational dysregulation in addiction |
Q37454695 | Appetitive motivational experience during adolescence results in enhanced alcohol consumption during adulthood |
Q34415017 | Assessment of GABA-B, metabotropic glutamate, and opioid receptor involvement in an animal model of binge drinking |
Q88626650 | Baclofen and naltrexone effects on alcohol self-administration: Comparison of treatment initiated during abstinence or ongoing alcohol access in baboons |
Q40231786 | Baclofen blocks expression and sensitization of anxiety-like behavior in an animal model of repeated stress and ethanol withdrawal |
Q64108929 | Baclofen but Not Diazepam Alleviates Alcohol-Seeking Behavior and Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Stressed Withdrawn Mice |
Q41844916 | Baclofen effects on alcohol seeking, self-administration and extinction of seeking responses in a within-session design in baboons |
Q93360935 | Baclofen for alcohol use disorder |
Q94326378 | Baclofen for alcohol use disorder |
Q36474092 | Baclofen in the management of inhalant withdrawal: a case series. |
Q35039864 | Bidirectional enantioselective effects of the GABAB receptor agonist baclofen in two mouse models of excessive ethanol consumption. |
Q33635710 | Biobehavioral effects of baclofen in anxious alcohol-dependent individuals: a randomized, double-blind, placebo-controlled, laboratory study |
Q34693009 | CGP7930: a positive allosteric modulator of the GABAB receptor. |
Q36807235 | CRF enhancement of GIRK channel-mediated transmission in dopamine neurons |
Q35161340 | Ceftriaxone and cefazolin attenuate the cue-primed reinstatement of alcohol-seeking |
Q36430894 | Chronic Intracerebroventricular Infusion of Monocyte Chemoattractant Protein-1 Leads to a Persistent Increase in Sweetened Ethanol Consumption During Operant Self-Administration But Does Not Influence Sucrose Consumption in Long-Evans Rats |
Q41458616 | Chronic Nicotine Exposure Initiated in Adolescence and Unpaired to Behavioral Context Fails to Enhance Sweetened Ethanol Seeking |
Q36095127 | Comparison of the effect of the GABAΒ receptor agonist, baclofen, and the positive allosteric modulator of the GABAB receptor, GS39783, on alcohol self-administration in 3 different lines of alcohol-preferring rats |
Q36644242 | Conceptualizing withdrawal-induced escalation of alcohol self-administration as a learned, plasticity-dependent process |
Q36033490 | Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats |
Q37357463 | Corticotropin-releasing factor-1 receptor antagonists decrease heroin self-administration in long- but not short-access rats |
Q37383571 | Development of pharmacotherapies for drug addiction: a Rosetta stone approach |
Q52301706 | Differential effects of baclofen and oxytocin on the increased ethanol consumption following chronic psychosocial stress in mice. |
Q35956492 | Differential effects of ghrelin antagonists on alcohol drinking and reinforcement in mouse and rat models of alcohol dependence |
Q33566730 | Differential involvement of GABAA and GABAB receptors in propofol self-administration in rats |
Q37458269 | Dissociating Motivational From Physiological Withdrawal in Alcohol Dependence: Role of Central Amygdala κ-Opioid Receptors |
Q47637909 | Drosophila: An Emergent Model for Delineating Interactions between the Circadian Clock and Drugs of Abuse. |
Q39365977 | Dysregulation of Brain Stress Systems Mediates Compulsive Alcohol Drinking |
Q36532370 | Effects of adolescent onset voluntary drinking followed by ethanol vapor exposure on subsequent ethanol consumption during protracted withdrawal in adult Wistar rats |
Q34194388 | Effects of prolonged ethanol vapor exposure on forced swim behavior, and neuropeptide Y and corticotropin-releasing factor levels in rat brains |
Q34254875 | Effects of β-adrenoceptor antagonists on alcohol drinking by alcohol-dependent rats. |
Q34246904 | Efficacy and safety of baclofen for alcohol dependence: a randomized, double-blind, placebo-controlled trial |
Q52590630 | Efficacy and side effects of baclofen and the novel GABAB receptor positive allosteric modulator CMPPE in animal models for alcohol and cocaine addiction. |
Q38115144 | Efficacy and tolerability of baclofen in substance use disorders: a systematic review |
Q46478974 | Electroacupuncture reduces voluntary alcohol intake in alcohol-preferring rats via an opiate-sensitive mechanism |
Q37766239 | Emerging drugs to treat alcoholism |
Q38689594 | Emerging pharmacotherapies for alcohol use disorder |
Q37400689 | Escalation of drug self-administration as a hallmark of persistent addiction liability |
Q89292099 | Ethanol Reinforcement Elicits Novel Response Inhibition Behavior in a Rat Model of Ethanol Dependence |
Q36713890 | Ethanol dually modulates GABAergic synaptic transmission onto dopaminergic neurons in ventral tegmental area: role of mu-opioid receptors |
Q41828000 | Ethanol induces stronger dopamine release in nucleus accumbens (shell) of alcohol-preferring (bibulous) than in alcohol-avoiding (abstainer) rats. |
Q37625560 | Ethanol self-administration in serotonin transporter knockout mice: unconstrained demand and elasticity |
Q34356376 | GABA(A) receptors in the dorsal raphé nucleus of mice: escalation of aggression after alcohol consumption |
Q27026530 | GABAB receptor ligands for the treatment of alcohol use disorder: preclinical and clinical evidence |
Q37775215 | GABAB receptors in reward processes |
Q36672572 | GABAergic modulation of binge-like ethanol intake in C57BL/6J mice |
Q33572392 | Hedonic Homeostatic Dysregulation as a Driver of Drug-Seeking Behavior |
Q34073903 | How adaptation of the brain to alcohol leads to dependence: a pharmacological perspective. |
Q37309654 | Increased Ethanol Consumption Following Chronic Psychosocial Stress: Do Oxytocin and Baclofen Hold any Therapeutic Promise? |
Q92716256 | Inducing Alcohol Dependence in Rats Using Chronic Intermittent Exposure to Alcohol Vapor |
Q34642726 | Is baclofen a revolutionary medication in alcohol addiction management? Review and recent updates |
Q26767487 | Lipids and Oxidative Stress Associated with Ethanol-Induced Neurological Damage |
Q33848861 | Long-Evans rats acquire operant self-administration of 20% ethanol without sucrose fading |
Q90740642 | Maladaptive behavioral regulation in alcohol dependence: Role of kappa-opioid receptors in the bed nucleus of the stria terminalis |
Q38718932 | Medications development for the treatment of alcohol use disorder: insights into the predictive value of animal and human laboratory models |
Q34607261 | Multi-center trial of baclofen for abstinence initiation in severe cocaine-dependent individuals |
Q37405045 | Neurobiology of alcohol dependence: focus on motivational mechanisms. |
Q37638007 | Neurobiology of consummatory behavior: mechanisms underlying overeating and drug use. |
Q38259371 | Neurochemical mechanisms of alcohol withdrawal. |
Q26995739 | Neuropeptide modulation of central amygdala neuroplasticity is a key mediator of alcohol dependence. |
Q26853630 | Novel therapeutic strategies for alcohol and drug addiction: focus on GABA, ion channels and transcranial magnetic stimulation |
Q33555941 | Operant alcohol self-administration in dependent rats: focus on the vapor model |
Q37463676 | Operant behavior and alcohol levels in blood and brain of alcohol-dependent rats |
Q35142973 | Operant self-administration of sweetened ethanol and time course of blood ethanol levels in adolescent and adult male Long-Evans rats |
Q24658266 | Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence |
Q42721730 | Pharmacologically targeting the P2rx4 gene on maintenance and reinstatement of alcohol self-administration in rats |
Q35141550 | Plasticity associated with escalated operant ethanol self-administration during acute withdrawal in ethanol-dependent rats requires intact matrix metalloproteinase systems |
Q36074885 | Positive allosteric modulation of the GABA(B) receptor by GS39783 attenuates the locomotor stimulant actions of ethanol and potentiates the induction of locomotor sensitization |
Q38268791 | Postdependent state in rats as a model for medication development in alcoholism |
Q33693932 | Predicting extinction and reinstatement of alcohol and sucrose self-administration in outbred rats |
Q51855387 | Pregabalin reduces alcohol drinking and relapse to alcohol seeking in the rat. |
Q34380302 | Prenatal and postnatal ethanol experiences modulate consumption of the drug in rat pups, without impairment in the granular cell layer of the main olfactory bulb. |
Q36805735 | R(+)-Baclofen, but Not S(-)-Baclofen, Alters Alcohol Self-Administration in Alcohol-Preferring Rats |
Q34613495 | Reducing effect of the positive allosteric modulator of the GABA(B) receptor, GS39,783, on alcohol self-administration in alcohol-preferring rats |
Q42001372 | Reduction of excessive alcohol drinking by a novel GABAB receptor positive allosteric modulator ADX71441 in mice |
Q36867025 | Regulation of motivation to self-administer ethanol by mGluR5 in alcohol-preferring (P) rats. |
Q58288722 | Reply to the Letter “Are the Effects of Gamma-Hydroxybutyrate (GHB) Treatment Partly Physiological in Alcohol Dependence?” by Olivier Ameisen |
Q33904842 | Schedule of passive ethanol exposure affects subsequent intragastric ethanol self-infusion |
Q41458899 | Serotonin2C receptors in the nucleus accumbens are involved in enhanced alcohol-drinking behavior |
Q37318993 | Site-specific microinjection of baclofen into the anterior ventral tegmental area reduces binge-like ethanol intake in male C57BL/6J mice |
Q30449836 | Stress history increases alcohol intake in relapse: relation to phosphodiesterase 10A. |
Q57490270 | Suppressing Effect of Baclofen on Multiple Alcohol-Related Behaviors in Laboratory Animals |
Q39096987 | Synaptic targets: Chronic alcohol actions |
Q36092808 | Targeting dynorphin/kappa opioid receptor systems to treat alcohol abuse and dependence |
Q38907719 | The GABAB Positive Allosteric Modulator ADX71441 Attenuates Alcohol Self-Administration and Relapse to Alcohol Seeking in Rats. |
Q60920774 | The Use of Baclofen as a Treatment for Alcohol Use Disorder: A Clinical Practice Perspective |
Q36526507 | The central amygdala and alcohol: role of γ-aminobutyric acid, glutamate, and neuropeptides |
Q36164923 | The effect of intermittent alcohol vapor or pulsatile heroin on somatic and negative affective indices during spontaneous withdrawal in Wistar rats |
Q34378869 | The neurobiology of alcohol consumption and alcoholism: an integrative history |
Q52311615 | The peroxisome proliferator-activated receptor alpha agonist fenofibrate attenuates alcohol self-administration in rats. |
Q34679845 | Tigecycline Reduces Ethanol Intake in Dependent and Nondependent Male and Female C57BL/6J Mice |
Q30275036 | Transient Adenosine Release Is Modulated by NMDA and GABAB Receptors |
Q53088311 | Utilization of baclofen in maintenance of alcohol abstinence in patients with alcohol dependence and alcoholic hepatitis with or without cirrhosis. |
Q36983396 | alpha1-noradrenergic receptor antagonism blocks dependence-induced increases in responding for ethanol |
Q37638946 | κ-opioid receptors are implicated in the increased potency of intra-accumbens nalmefene in ethanol-dependent rats |
Search more.