Association of a serotonin transporter polymorphism (5-HTTLPR) with depression, perceived stress, and norepinephrine in patients with coronary disease: the Heart and Soul Study

scientific article published on September 2007

Association of a serotonin transporter polymorphism (5-HTTLPR) with depression, perceived stress, and norepinephrine in patients with coronary disease: the Heart and Soul Study is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1176/APPI.AJP.2007.06101617
P932PMC publication ID2771565
P698PubMed publication ID17728423
P5875ResearchGate publication ID6112822

P50authorMary A. WhooleyQ56332432
Christian OtteQ64732257
P2093author name stringSadia Ali
Jeanne McCaffery
P2860cites workSerotonin transporter gene promoter region polymorphism associated with poststroke major depressionQ46981424
Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood plateletsQ48273381
Stress-related negative affectivity and genetically altered serotonin transporter function: evidence of synergism in shaping risk of depression.Q50926497
A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity.Q51408749
Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression.Q51913092
National Institute of Mental Health Diagnostic Interview Schedule. Its history, characteristics, and validity.Q52101976
What makes a good genetic association study?Q57943305
Evidence of a Selective Increase in Cardiac Sympathetic Activity in Patients with Sustained Ventricular ArrhythmiasQ67927748
Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failureQ70376386
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT geneQ27860482
Social adversity, the serotonin transporter (5-HTTLPR) polymorphism and major depressive disorderQ28271610
Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory regionQ28297391
A global measure of perceived stressQ29547166
Depression and anxiety in Parkinson's disease: possible effect of genetic variation in the serotonin transporterQ33873790
The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variantsQ33889977
Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traitsQ34316352
Allelic variation of human serotonin transporter gene expressionQ34379938
The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depressionQ34412692
The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replicationQ34415485
Genetic association mapping at the crossroads: which test and why? Overview and practical guidelinesQ34526866
Treatment of mood disordersQ34982300
Common genetic vulnerability to depressive symptoms and coronary artery disease: a review and development of candidate genes related to inflammation and serotoninQ36428787
Neuroimaging studies of serotonin gene polymorphisms: exploring the interplay of genes, brain, and behaviorQ36547543
Depression and cardiovascular disease: healing the broken-heartedQ37407363
Depression and 24-hour urinary cortisol in medical outpatients with coronary heart disease: The Heart and Soul StudyQ37419673
Depressive symptoms and health-related quality of life: the Heart and Soul StudyQ37419710
Depressive symptoms and 24-hour urinary norepinephrine excretion levels in patients with coronary disease: findings from the Heart and Soul StudyQ37419720
Social supports and serotonin transporter gene moderate depression in maltreated childrenQ37691315
Allelic variation of serotonin transporter expression is associated with depression in Parkinson's disease.Q43590767
Detection of depressive disorder for patients receiving prepaid or fee-for-service care. Results from the Medical Outcomes StudyQ43794858
Exaggerated adrenomedullary response to immobilization in mice with targeted disruption of the serotonin transporter geneQ44225977
Changes in brain natriuretic peptide and norepinephrine over time and mortality and morbidity in the Valsartan Heart Failure Trial (Val-HeFT).Q44357138
Allelic variation in the serotonin transporter gene-linked polymorphic region (5-HTTLPR) and cardiovascular reactivity in young adult male and female twins of European-American descentQ44595386
Gene-environment interaction analysis of serotonin system markers with adolescent depressionQ44969252
Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burdenQ44985819
Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depressionQ45134204
The power of sample size and homogenous sampling: association between the 5-HTTLPR serotonin transporter polymorphism and major depressive disorderQ45251042
Association of the serotonin transporter gene-linked polymorphic region (5-HTTLPR) genotype with depression in elderly persons after hip fractureQ46477857
Influence of serotonin transporter gene polymorphism on depressive symptoms and new cardiac events after acute myocardial infarctionQ46739661
Life events, first depression onset and the serotonin transporter geneQ46968877
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectserotoninQ167934
patientQ181600
norepinephrineQ186242
P304page(s)1379-1384
P577publication date2007-09-01
P1433published inAmerican Journal of PsychiatryQ1935368
P1476titleAssociation of a serotonin transporter polymorphism (5-HTTLPR) with depression, perceived stress, and norepinephrine in patients with coronary disease: the Heart and Soul Study
P478volume164

Reverse relations

cites work (P2860)
Q481247735-HTTLPR genotype, asthma, diabetes and late-life depression in an older French population.
Q33678812A prospective cohort study investigating factors associated with depression during medical internship
Q37866294A topographical map of the causal network of mechanisms underlying the relationship between major depressive disorder and coronary heart disease.
Q34201923Association between a serotonin transporter gene variant and hopelessness among men in the Heart and Soul Study
Q48305576Association of 5-HTR2A and 5-HTR2C serotonin receptor gene polymorphisms with depression risk in patients with coronary heart disease
Q37429799Association of depressive and anxiety symptoms with 24-hour urinary catecholamines in individuals with untreated high blood pressure.
Q35186571Association of functional polymorphisms from brain-derived neurotrophic factor and serotonin-related genes with depressive symptoms after a medical stressor in older adults
Q43104615Association of the 5- HTTLPR genotype and unipolar depression: a meta-analysis
Q48191933Associations of cytokine genes with Alzheimer's disease and depression in an elderly Korean population
Q37529769Cardiovascular abnormalities in patients with major depressive disorder: autonomic mechanisms and implications for treatment.
Q37255370Clinical implications of genetic variation in the serotonin transporter promoter region: a review
Q40917213Coexisting anxiety disorders alter associations with physical disorders in the elderly: A Taiwan cross-sectional nationwide study
Q38857411Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression.
Q27001175Comorbidity of depression with physical disorders: research and clinical implications
Q26752379Depression and the Link with Cardiovascular Disease
Q37599875Depression and the cardiovascular system: increasing evidence of a link and therapeutic implications
Q33781185Depression in older adults
Q47915544Depression in systemic lupus erythematosus patients is associated with link-polymorphism but not methylation status of the 5HTT promoter region
Q36483890Effects of Recent Stress and Variation in the Serotonin Transporter Polymorphism (5-HTTLPR) on Depressive Symptoms: A Repeated-Measures Study of Adults Age 50 and Older.
Q36741141Effects of depressive and anxious symptoms on norepinephrine and platelet P-selectin responses to acute psychological stress among elderly caregivers
Q34231919Emotion regulation moderates the risk associated with the 5-HTT gene and stress in children
Q61713904Functional Pharmacogenetics of Serotonin Receptors in Psychiatric Drug Action
Q34919789Gene-environment interactions in geriatric depression
Q37139308Genetic predictors of depressive symptoms in cardiac patients
Q47159397Genetic predisposition toward suicidal ideation in patients with acute coronary syndrome
Q33913961Genetic variation in 5HTTLPR is associated with emotional resilience
Q33869891Genetic vulnerability and phenotypic expression of depression and risk for ischemic heart disease in the Vietnam era twin study of aging
Q37526428Glia and immune cell signaling in bipolar disorder: insights from neuropharmacology and molecular imaging to clinical application
Q37419660Glucocorticoid receptor gene and depression in patients with coronary heart disease: the Heart and Soul Study-2009 Curt Richter Award Winner
Q34490176Health care insurance, financial concerns in accessing care, and delays to hospital presentation in acute myocardial infarction
Q33679060Healthy young women with serotonin transporter SS polymorphism show a pro-inflammatory bias under resting and stress conditions.
Q36104610Individual differences in delay discounting under acute stress: the role of trait perceived stress
Q36745354Inflammatory vulnerability associated with the rh5-HTTLPR genotype in juvenile rhesus monkeys
Q37662041Insurance and Prehospital Delay in Patients ≤55 Years With Acute Myocardial Infarction
Q35877150Monoamine transporters: vulnerable and vital doorkeepers
Q35090255Ontogeny and regulation of the serotonin transporter: providing insights into human disorders
Q34655157Pathophysiological basis of cardiovascular disease and depression: a chicken-and-egg dilemma
Q38664591Perceived stress and poly-tobacco product use across adolescence: Patterns of association and gender differences
Q37409451Persistent versus transient depressive symptoms in relation to platelet hyperactivation: a longitudinal analysis of dementia caregivers
Q33730306Pharmacogenetics of major depression: insights from level 1 of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial
Q37195327Platelets and depression in cardiovascular disease: A brief review of the current literature
Q45987544Poststroke depression and 5-HTTLPR.
Q36091174Response to psychosocial treatment in poststroke depression is associated with serotonin transporter polymorphisms
Q37761801Social support in smoking cessation: reconciling theory and evidence
Q47158772Stereological Study on the Positive Effect of Running Exercise on the Capillaries in the Hippocampus in a Depression Model
Q35082652The "S" Allele of the Serotonin Transporter Is Not Associated with Major Depression in a Sample OF Veterans
Q35858373The "S" Allele of the Serotonin Transporter Is Not Associated with Major Depression or Alcohol Use Disorders in a Veteran Sample.
Q40134586The 5-HTTLPR polymorphism in South African healthy populations: a global comparison
Q34980524The St. Louis African American health-heart study: methodology for the study of cardiovascular disease and depression in young-old African Americans
Q37066337The heritability of hedonic capacity and perceived stress: a twin study evaluation of candidate depressive phenotypes
Q90435519The important effect of 5-HTTLPR polymorphism on the risk of depression in patients with coronary heart disease: a meta-analysis
Q34020661The moderation by the serotonin transporter gene of environmental adversity in the etiology of depression: 2009 update
Q48141207The relationship between stress, hemispheric preference and decision making among managers
Q38103493The role of inflammatory cytokines on the aetiopathogenesis of depression
Q28274744The serotonin transporter polymorphism (5-HTTLPR): allelic variation and links with depressive symptoms
Q24289552The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation
Q37203368Treatment of post-myocardial infarction depressive disorder
Q80777874[Depression in chronic heart failure: complication, risk factor or autonomous disease?]

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