Vaccination with live Leishmania major and CpG DNA promotes interleukin-2 production by dermal dendritic cells and NK cell activation

scientific article published on 23 September 2009

Vaccination with live Leishmania major and CpG DNA promotes interleukin-2 production by dermal dendritic cells and NK cell activation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/CVI.00249-09
P932PMC publication ID2772372
P698PubMed publication ID19776191
P5875ResearchGate publication ID26833290

P2093author name stringSusana Mendez
Wenhui Wu
Eva Maria Laabs
P2860cites workActivation of invariant NKT cells exacerbates experimental visceral leishmaniasisQ27318814
Immunomodulatory effects associated with a live vaccine against Leishmania major containing CpG oligodeoxynucleotidesQ28510289
Interleukin-12 and the regulation of innate resistance and adaptive immunityQ29614602
An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrowQ29615498
Leishmaniasis: current situation and new perspectivesQ34330071
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunityQ34529549
The immunology of susceptibility and resistance to Leishmania major in miceQ34988360
Update on natural killer cells: cross-talk with dendritic cells and role in the cure of acute myeloid leukemiasQ35216156
Coinjection with CpG-containing immunostimulatory oligodeoxynucleotides reduces the pathogenicity of a live vaccine against cutaneous Leishmaniasis but maintains its potency and durabilityQ35802037
CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cellsQ35971414
Helper role of NK cells during the induction of anticancer responses by dendritic cellsQ35988425
Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in miceQ36362141
A contribution of mouse dendritic cell-derived IL-2 for NK cell activationQ36399726
Regulatory T-cell compartmentalization and traffickingQ36421407
Modulation of NK cell activity by CpG oligodeoxynucleotidesQ36961016
The role of the innate immune response in Th1 cell development following Leishmania major infection.Q40509369
Reciprocal activating interaction between natural killer cells and dendritic cellsQ41992239
Contact-dependent stimulation and inhibition of dendritic cells by natural killer cellsQ42005335
TLR-dependent activation stimuli associated with Th1 responses confer NK cell stimulatory capacity to mouse dendritic cells.Q46561897
Dendritic cells (DC) activated by CpG DNA ex vivo are potent inducers of host resistance to an intracellular pathogen that is independent of IL-12 derived from the immunizing DC.Q47644110
Early parasite containment is decisive for resistance to Leishmania major infection.Q54166265
Treatment of recurrent cutaneous Leishmaniasis.Q54181533
Cutaneous leishmaniasis: an increasing threat for travellers.Q54671661
Control of Leishmania major in the absence of Tyk2 kinase.Q54730490
A lipophosphoglycan-independent method for isolation of infective Leishmania metacyclic promastigotes by density gradient centrifugationQ77365877
Mice lacking NK cells develop an efficient Th1 response and control cutaneous Leishmania major infectionQ77823585
The interaction between NK cells and dendritic cells in bacterial infections results in rapid induction of NK cell activation and in the lysis of uninfected dendritic cellsQ78842088
Natural killer (NK) cell functions can be strongly boosted by activated dendritic cells (DC)Q79169943
NKT cells mediate organ-specific resistance against Leishmania major infectionQ81379952
Natural killer dendritic cells have both antigen presenting and lytic function and in response to CpG produce IFN-gamma via autocrine IL-12Q81434882
P433issue11
P921main subjectinterleukinsQ194908
Leishmania majorQ1950715
dermal dendritic cellQ113044521
P304page(s)1601-1606
P577publication date2009-09-23
P1433published inClinical and Vaccine ImmunologyQ5133811
P1476titleVaccination with live Leishmania major and CpG DNA promotes interleukin-2 production by dermal dendritic cells and NK cell activation
P478volume16

Reverse relations

cites work (P2860)
Q42670769A live Leishmania major vaccine containing CpG motifs induces the de novo generation of Th17 cells in C57BL/6 mice.
Q38008347Activation of natural killer cells during microbial infections
Q36021357Adjuvants for Leishmania vaccines: from models to clinical application
Q35102709CD4 T cell activation by B cells in human Leishmania (Viannia) infection
Q35571431Coinjection with TLR2 agonist Pam3CSK4 reduces the pathology of leishmanization in mice.
Q88510856Cutaneous Leishmaniasis: Update on Vaccine Development
Q38855600Identification of Toxoplasma gondii protein fractions induce immune response against melanoma in mice.
Q37811555Innate Immunity and Leishmania Vaccination Strategies
Q82941724Leishmania (Viannia) shawi purified antigens confer protection against murine cutaneous leishmaniasis
Q38037557Natural killer cells in experimental and human leishmaniasis
Q38015852Protective immunity and vaccination against cutaneous leishmaniasis.
Q38011653Therapeutic live vaccines as a potential anticancer strategy.
Q39180425Trichinella spiralis infection reduces tumor growth and metastasis of B16-F10 melanoma cells

Search more.