High prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity

scientific article published on 16 October 2009

High prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity is …
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scholarly articleQ13442814

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P356DOI10.1210/JC.2009-1333
P932PMC publication ID2775643
P698PubMed publication ID19837913

P50authorRichard S. LegroQ40316671
Andrea D CovielloQ47502307
P2093author name stringAndrea Dunaif
Susan Sam
P2860cites workExecutive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)Q27860959
Metabolic phenotype in the brothers of women with polycystic ovary syndromeQ33962557
Visceral fat accumulation in men is positively associated with insulin, glucose, and C-peptide levels, but negatively with testosterone levelsQ34227587
Evidence for metabolic and reproductive phenotypes in mothers of women with polycystic ovary syndromeQ34598493
The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994.Q35135723
Elevated dehydroepiandrosterone sulfate levels as the reproductive phenotype in the brothers of women with polycystic ovary syndrome.Q35597056
Dyslipidemia and metabolic syndrome in the sisters of women with polycystic ovary syndromeQ35597070
Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndromeQ35995837
Evidence for a genetic basis for hyperandrogenemia in polycystic ovary syndrome.Q36758555
The link between abdominal obesity and the metabolic syndromeQ37161474
Evidence for pancreatic beta-cell dysfunction in brothers of women with polycystic ovary syndromeQ37262330
Brothers of women with polycystic ovary syndrome are characterised by impaired glucose tolerance, reduced insulin sensitivity and related metabolic defectsQ37355732
Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts male aging studyQ40760488
Metabolic profile in sons of women with polycystic ovary syndromeQ42524146
Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo studyQ43843236
Prevalence of Type II diabetes mellitus and insulin resistance in parents of women with polycystic ovary syndrome.Q44075861
A comparison of the prevalence of the metabolic syndrome using two proposed definitionsQ44333376
Glucose Intolerance, Insulin Resistance, and Hyperandrogenemia in First Degree Relatives of Women with Polycystic Ovary SyndromeQ44427438
The androgenic sex hormone profile is an essential feature of metabolic syndrome in premenopausal women: a controlled community-based studyQ44473188
Low sex hormone-binding globulin, total testosterone, and symptomatic androgen deficiency are associated with development of the metabolic syndrome in nonobese men.Q44685104
Dose-dependent effects of testosterone on regional adipose tissue distribution in healthy young men.Q44757133
Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men.Q44865591
Measures of insulin resistance add incremental value to the clinical diagnosis of metabolic syndrome in association with coronary atherosclerosisQ45004056
Glucose and insulin components of the metabolic syndrome are associated with hyperandrogenism in postmenopausal women: the atherosclerosis risk in communities studyQ45048805
The metabolic syndrome and smoking in relation to hypogonadism in middle-aged men: a prospective cohort studyQ45145832
Relative risks of the metabolic syndrome according to the degree of insulin resistance in apparently healthy Korean adultsQ45237797
Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistanceQ46774556
Relationship of adolescent polycystic ovary syndrome to parental metabolic syndromeQ46921371
Low levels of sex hormone-binding globulin and testosterone predict the development of non-insulin-dependent diabetes mellitus in men. MRFIT Research Group. Multiple Risk Factor Intervention Trial.Q51035704
Identification of a polycystic ovary syndrome susceptibility variant in fibrillin-3 and association with a metabolic phenotype.Q51464160
Treatment with flutamide, metformin, and their combination added to a hypocaloric diet in overweight-obese women with polycystic ovary syndrome: a randomized, 12-month, placebo-controlled study.Q51494027
Testosterone concentrations in women and men with NIDDM.Q51595541
Polycystic Ovary SyndromeQ56092373
Lower endogenous androgens predict central adiposity in menQ67875625
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectobesityQ12174
polycystic ovary syndromeQ500816
metabolic syndromeQ657193
polycystic ovaryQ5547896
P304page(s)4361-4366
P577publication date2009-10-16
P1433published inThe Journal of Clinical Endocrinology and MetabolismQ3186902
P1476titleHigh prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity
P478volume94

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cites work (P2860)
Q48138914A Single Bout of Electroacupuncture Remodels Epigenetic and Transcriptional Changes in Adipose Tissue in Polycystic Ovary Syndrome.
Q41108966Adverse metabolic phenotype of adolescent girls with non-alcoholic fatty liver disease plus polycystic ovary syndrome compared with other girls and boys
Q36334951Altered glucose disposition and insulin sensitivity in peri-pubertal first-degree relatives of women with polycystic ovary syndrome
Q34878055Assessing and treating insulin resistance in women with polycystic ovarian syndrome
Q85029538Berberine reduces insulin resistance induced by dexamethasone in theca cells in vitro
Q50056959Cardiometabolic Risk in PCOS: More than a Reproductive Disorder
Q89802309Could perturbed fetal development of the ovary contribute to the development of polycystic ovary syndrome in later life?
Q35906974Defining the role of bariatric surgery in polycystic ovarian syndrome patients
Q36360786Emerging concepts about prenatal genesis, aberrant metabolism and treatment paradigms in polycystic ovary syndrome.
Q39502485Establishment of polycystic ovary syndrome-derived human embryonic stem cell lines
Q30303066Evidence for gonadotrophin secretory and steroidogenic abnormalities in brothers of women with polycystic ovary syndrome
Q35108260Evidence for increased cardiovascular events in the fathers but not mothers of women with polycystic ovary syndrome
Q36607455Familial aggregation of circulating C-reactive protein in polycystic ovary syndrome
Q37060258Increased antimüllerian hormone levels and other reproductive endocrine changes in adult male relatives of women with polycystic ovary syndrome
Q36429617Maternal characteristics and pregnancy outcomes after assisted reproductive technology by infertility diagnosis: ovulatory dysfunction versus tubal obstruction
Q36306120Maternal testosterone exposure increases anxiety-like behavior and impacts the limbic system in the offspring
Q40946230Metabolic and Reproductive Consequences of the Polycystic Ovary Syndrome (PCOS)
Q50056205Metabolic syndrome, hypertension, and hyperlipidemia in mothers, fathers, sisters, and brothers of women with polycystic ovary syndrome: a systematic review and meta-analysis
Q30371644Parent-of-origin effects on glucose homeostasis in polycystic ovary syndrome.
Q36716040Perspectives in Polycystic Ovary Syndrome: From Hair to Eternity
Q88098767Polycystic ovary syndrome
Q37832125Polycystic ovary syndrome: etiology, pathogenesis and diagnosis
Q33750469Prevalence of metabolic syndrome in the family members of women with polycystic ovary syndrome from North India
Q28390200Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome
Q28395801Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus
Q35233754State of the Art Review: Emerging Therapies: The Use of Insulin Sensitizers in the Treatment of Adolescents with Polycystic Ovary Syndrome (PCOS).
Q92059141Synergistic Effects of Hyperandrogenemia and Obesogenic Western-style Diet on Transcription and DNA Methylation in Visceral Adipose Tissue of Nonhuman Primates
Q41640666The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited
Q91636068Transgenerational Inheritance of Reproductive and Metabolic Phenotypes in PCOS Rats

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