scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1002634268 |
P356 | DOI | 10.1007/S12263-009-0143-4 |
P932 | PMC publication ID | 2775893 |
P698 | PubMed publication ID | 19756809 |
P5875 | ResearchGate publication ID | 26814609 |
P50 | author | Orly Weinreb | Q67224441 |
Silvia A. Mandel | Q67237925 | ||
Moussa B. H. Youdim | Q16105430 | ||
P2093 | author name string | Tamar Amit | |
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(-)-Epigallocatechin-3-gallate prevents lipopolysaccharide-induced elevation of beta-amyloid generation and memory deficiency | Q46257745 | ||
Green tea polyphenol (-)-epigallocatechin-3-gallate induces neurorescue of long-term serum-deprived PC12 cells and promotes neurite outgrowth | Q46526631 | ||
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Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice. | Q46715173 | ||
Green tea catechins prevent cognitive deficits caused by Abeta1-40 in rats | Q46749043 | ||
Attenuation of senescence-induced oxidative exacerbations in aged rat brain by (-)-epigallocatechin-3-gallate | Q46799465 | ||
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Apomorphine protects against MPTP-induced neurotoxicity in mice | Q48144127 | ||
Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients | Q48191627 | ||
The antioxidative property of green tea against iron-induced oxidative stress in rat brain | Q48250461 | ||
The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons. | Q48257428 | ||
Pharmacokinetics of (-)-epigallocatechin-3-gallate in conscious and freely moving rats and its brain regional distribution | Q48296640 | ||
Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue | Q48356106 | ||
Uptake and distribution of catechins in fetal organs following in utero exposure in rats | Q48426168 | ||
Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains | Q48789036 | ||
Diet and Parkinson's disease. I: A possible role for the past intake of specific foods and food groups. Results from a self-administered food-frequency questionnaire in a case-control study | Q48935400 | ||
The enhancing effect of tumour necrosis factor-alpha on oxidative stress in endotoxemia | Q50137017 | ||
Green tea does not inhibit iron absorption. | Q50652576 | ||
Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project 1. | Q50739872 | ||
Brain iron and ferritin in Parkinson's and Alzheimer's diseases. | Q53184175 | ||
Oxidative stress: free radical production in neural degeneration. | Q53205007 | ||
Neuroprotective effects of (-)-epigallocatechin-3-gallate in a transgenic mouse model of amyotrophic lateral sclerosis. | Q53595328 | ||
Increased levels of 14-3-3 gamma and epsilon proteins in brain of patients with Alzheimer's disease and Down syndrome | Q58365395 | ||
Time Course of the Translocation and Inhibition of Protein kinase C During Complete Cerebral Ischemia in the Rat | Q60597242 | ||
Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains | Q61714001 | ||
Stability of flavonoid complexes of copper(II) and flavonoid antioxidant activity | Q67805617 | ||
Antioxidant and iron-chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures | Q70540181 | ||
Ca2+-dependent and Ca2+-independent protein kinase C changes in the brain of patients with Alzheimer's disease | Q71152177 | ||
Structural aspects of antioxidant activity of flavonoids | Q71294326 | ||
Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical | Q71747211 | ||
Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants | Q71778889 | ||
Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes | Q71942060 | ||
Regional alterations of protein kinase C activity following transient cerebral ischemia: effects of intraischemic brain temperature modulation | Q72109089 | ||
Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenols | Q73283883 | ||
Radical scavenging activity of tea catechins and their related compounds | Q73300163 | ||
Chemiluminescence-high-performance liquid chromatographic determination of tea catechin, (-)-epigallocatechin 3-gallate, at picomole levels in rat and human plasma | Q73401983 | ||
(-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB | Q73661590 | ||
Iron, neuromelanin and ferritin content in the substantia nigra of normal subjects at different ages: consequences for iron storage and neurodegenerative processes | Q22337213 | ||
Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1 | Q24564855 | ||
Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease | Q24657243 | ||
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation | Q27860876 | ||
Neurotrophin signal transduction in the nervous system | Q27876223 | ||
Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease | Q28215872 | ||
Flavonoids: antioxidants or signalling molecules? | Q28250292 | ||
Green tea composition, consumption, and polyphenol chemistry | Q28271284 | ||
Catechin metabolites after intake of green tea infusions | Q28279143 | ||
Flavonoids: modulators of brain function? | Q28281453 | ||
Structural identification of two metabolites of catechins and their kinetics in human urine and blood after tea ingestion | Q28373564 | ||
Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, [...] | Q28376328 | ||
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis | Q29547567 | ||
Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms | Q31967393 | ||
14-3-3 proteins in the nervous system | Q33188355 | ||
Tea flavonols in cardiovascular disease and cancer epidemiology | Q33593245 | ||
Inhibition of carcinogenesis by tea: bioavailability of tea polyphenols and mechanisms of actions | Q33593258 | ||
Regulation of the iron regulatory proteins by reactive nitrogen and oxygen species. | Q33706925 | ||
Identification of the major antioxidative metabolites in biological fluids of the rat with ingested (+)-catechin and (-)-epicatechin | Q33869495 | ||
Beneficial effects of green tea--a review. | Q33994592 | ||
Protein kinase C isozymes and the regulation of diverse cell responses | Q34012841 | ||
Hypoxia-inducible factor-1 activation by (-)-epicatechin gallate: potential adverse effects of cancer chemoprevention with high-dose green tea extracts | Q34038797 | ||
Multicomponent therapeutics for networked systems | Q34390417 | ||
Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment | Q34400646 | ||
Bioavailability of flavan-3-ols and procyanidins: gastrointestinal tract influences and their relevance to bioactive forms in vivo | Q34507722 | ||
Theaflavin-3,3'-digallate from black tea blocks the nitric oxide synthase by down-regulating the activation of NF-kappaB in macrophages | Q40967012 | ||
Hypoxia post-translationally activates iron-regulatory protein 2. | Q40973622 | ||
Green tea polyphenols block endotoxin-induced tumor necrosis factor-production and lethality in a murine model | Q40985547 | ||
A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis | Q41008797 | ||
Overexpression of protein kinase C isoform epsilon but not delta in human interleukin-3-dependent cells suppresses apoptosis and induces bcl-2 expression | Q41069079 | ||
Vitamin C: antioxidant or pro-oxidant in vivo? | Q41197203 | ||
Antioxidants in tea. | Q41691968 | ||
Specific role for protein kinase C alpha in the constitutive and regulated secretion of amyloid precursor protein in human skin fibroblasts | Q42451549 | ||
Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase C alpha. | Q42508993 | ||
6-Hydroxydopamine releases iron from ferritin and promotes ferritin-dependent lipid peroxidation | Q43529349 | ||
Effects of R- and S-apomorphine on MPTP-induced nigro-striatal dopamine neuronal loss | Q43560464 | ||
Free radical scavenging by green tea polyphenols | Q43635874 | ||
Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration | Q43735211 | ||
Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-kappaB) activation and cell death by tea extracts in neuronal cultures | Q43832105 | ||
Amyloid-beta(25-35) impairs memory and increases NO in the temporal cortex of rats | Q43856299 | ||
The green tea polyphenol (-)-epigallocatechin gallate attenuates beta-amyloid-induced neurotoxicity in cultured hippocampal neurons | Q43866733 | ||
Involvement of protein kinase C activation and cell survival/ cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action | Q44023075 | ||
An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript | Q44116151 | ||
(-)Epicatechin stimulates ERK-dependent cyclic AMP response element activity and up-regulates GluR2 in cortical neurons. | Q44245674 | ||
Uptake and metabolism of epicatechin and its access to the brain after oral ingestion | Q44253246 | ||
Effects of green tea polyphenols on dopamine uptake and on MPP+ -induced dopamine neuron injury | Q44258713 | ||
Inhibitory activity of epigallocatechin gallate (EGCg) in paraquat-induced microsomal lipid peroxidation--a mechanism of protective effects of EGCg against paraquat toxicity | Q44264034 | ||
Estrogen activates protein kinase C in neurons: role in neuroprotection | Q44339851 | ||
cDNA gene expression profile homology of antioxidants and their antiapoptotic and proapoptotic activities in human neuroblastoma cells | Q44355279 | ||
Factors affecting the levels of tea polyphenols and caffeine in tea leaves | Q44366235 | ||
Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate | Q44387375 | ||
Enzymology of Methylation of Tea Catechins and Inhibition of Catechol-O-methyltransferase by (−)-Epigallocatechin Gallate | Q44403618 | ||
Gene and protein expression profiles of anti- and pro-apoptotic actions of dopamine, R-apomorphine, green tea polyphenol (-)-epigallocatechine-3-gallate, and melatonin | Q44508353 | ||
Parkinson's disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake | Q34522327 | ||
Interaction between flavonoids and the blood-brain barrier: in vitro studies | Q34532166 | ||
Tea as a functional food for oral health. | Q34621732 | ||
Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice | Q34656230 | ||
Mechanisms of chronic disease causation by nutritional factors and tobacco products and their prevention by tea polyphenols | Q34687918 | ||
Antioxidants and oxidants regulated signal transduction pathways | Q34816005 | ||
Multifunctional neuroprotective derivatives of rasagiline as anti-Alzheimer's disease drugs | Q34911093 | ||
MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide | Q34977017 | ||
Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions | Q35066981 | ||
The 14-3-3 protein epsilon isoform expressed in reactive astrocytes in demyelinating lesions of multiple sclerosis binds to vimentin and glial fibrillary acidic protein in cultured human astrocytes | Q35103017 | ||
Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration | Q35327851 | ||
Reactive oxygen species and the central nervous system | Q35389986 | ||
Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: implications for neurodegenerative diseases. | Q35686124 | ||
HIF1 and oxygen sensing in the brain | Q35777630 | ||
Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases | Q35879628 | ||
Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway | Q36163364 | ||
The beneficial effects of fruit polyphenols on brain aging | Q36272245 | ||
Mechanisms of action of green tea catechins, with a focus on ischemia-induced neurodegeneration. | Q36380401 | ||
Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease | Q36659955 | ||
Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress | Q36753387 | ||
Green tea catechins as brain-permeable, non toxic iron chelators to "iron out iron" from the brain | Q36797098 | ||
Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system | Q36980763 | ||
Differential effects of black versus green tea on risk of Parkinson's disease in the Singapore Chinese Health Study | Q37044339 | ||
Benefits from dietary polyphenols for brain aging and Alzheimer's disease | Q37139469 | ||
The interactions of flavonoids within neuronal signalling pathways | Q37292416 | ||
Oxidative stress: a role in the pathogenesis of Parkinson's disease | Q37935459 | ||
Multiple, conserved iron-responsive elements in the 3'-untranslated region of transferrin receptor mRNA enhance binding of iron regulatory protein 2. | Q38363493 | ||
Green tea extract increases cyclophosphamide-induced teratogenesis by modulating the expression of cytochrome P-450 mRNA. | Q38497299 | ||
The application of proteomics for studying the neurorescue activity of the polyphenol (-)-epigallocatechin-3-gallate | Q40022059 | ||
A novel approach of proteomics and transcriptomics to study the mechanism of action of the antioxidant-iron chelator green tea polyphenol (-)-epigallocatechin-3-gallate | Q40104979 | ||
Green tea polyphenol (-) -epigallocatechin-3-gallate promotes the rapid protein kinase C- and proteasome-mediated degradation of Bad: implications for neuroprotection | Q40199224 | ||
Reduction of iron-regulated amyloid precursor protein and beta-amyloid peptide by (-)-epigallocatechin-3-gallate in cell cultures: implications for iron chelation in Alzheimer's disease | Q40304504 | ||
Epigallocatechin gallate inhibits HIF-1alpha degradation in prostate cancer cells | Q40399994 | ||
Epigallocatechin gallate inhibits aryl hydrocarbon receptor gene transcription through an indirect mechanism involving binding to a 90 kDa heat shock protein | Q40442100 | ||
The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL. | Q40445219 | ||
Phospholipase C, protein kinase C, Ca2+/calmodulin-dependent protein kinase II, and redox state are involved in epigallocatechin gallate-induced phospholipase D activation in human astroglioma cells | Q40524337 | ||
Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases. | Q40602773 | ||
Epigallocatechin 3-gallate attenuates neuronal damage induced by 3-hydroxykynurenine | Q40603308 | ||
Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease | Q40635431 | ||
The future of neuroprotection | Q40778925 | ||
How protein kinase C activation protects nerve cells from oxidative stress-induced cell death. | Q40811572 | ||
Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death | Q40832650 | ||
Neuroprotection by MAPK/ERK kinase inhibition with U0126 against oxidative stress in a mouse neuronal cell line and rat primary cultured cortical neurons | Q40870467 | ||
Suppression of lipopolysaccharide-induced nuclear factor-kappaB activity by theaflavin-3,3'-digallate from black tea and other polyphenols through down-regulation of IkappaB kinase activity in macrophages | Q40904856 | ||
P433 | issue | 4 | |
P304 | page(s) | 283-296 | |
P577 | publication date | 2009-09-10 | |
P1433 | published in | Genes & Nutrition | Q19850987 |
P1476 | title | Neuroprotective molecular mechanisms of (-)-epigallocatechin-3-gallate: a reflective outcome of its antioxidant, iron chelating and neuritogenic properties | |
P478 | volume | 4 |
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