Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma

scientific article

Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.1367
P932PMC publication ID3875777
P698PubMed publication ID24243817
P5875ResearchGate publication ID258638659

P2093author name stringYu-Sun Chang
Kai-Ping Chang
Cheng-Lung Hsu
Chia-Chun Chen
Hsin-Pai Li
I-Che Chung
Chen-Ching Peng
Mei-Yuan Huang
Shao-Tung Huang
P2860cites workPrevalence of the initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATA-less core promotersQ24674136
Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal development in the rostral hindbrainQ28143128
Specificity of HOX protein function depends on DNA-protein and protein-protein interactions, both mediated by the homeo domainQ28238648
Hoxa2 downregulates Six2 in the neural crest-derived mesenchymeQ28506264
Six2 functions redundantly immediately downstream of Hoxa2Q28588717
Functions of DNA methylation: islands, start sites, gene bodies and beyondQ29547260
Epigenetics in cancerQ29547853
p300/CBP proteins: HATs for transcriptional bridges and scaffoldsQ29617981
MethPrimer: designing primers for methylation PCRsQ29618664
Homeobox genes and cancerQ33545679
Increased expression of MMP9 is correlated with poor prognosis of nasopharyngeal carcinomaQ33599264
Matrix metalloproteinase 9 expression is induced by Epstein-Barr virus latent membrane protein 1 C-terminal activation regions 1 and 2.Q33815241
Matrix metalloproteinases: biologic activity and clinical implicationsQ33849967
The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferasesQ34099074
Expression of matrix metalloproteinase 9 in nasopharyngeal carcinoma and association with Epstein-Barr virus infectionQ34423236
Hox genes and their candidate downstream targets in the developing central nervous systemQ34439668
Nasopharyngeal carcinomas: an updateQ35548696
The pathophysiology of HOX genes and their role in cancer.Q36005947
The expression of matrix metalloproteinase 9 is enhanced by Epstein-Barr virus latent membrane protein 1Q36006767
HOX genes: seductive science, mysterious mechanismsQ36386317
Cytosine methylation profiling of cancer cell lines.Q36534546
Proteins that bind methylated DNA and human cancer: reading the wrong wordsQ36740636
Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3.Q37301260
The curious case of the tumour virus: 50 years of Burkitt's lymphomaQ37325443
The antiapoptotic protein, FLIP, is regulated by heterogeneous nuclear ribonucleoprotein K and correlates with poor overall survival of nasopharyngeal carcinoma patients.Q38345812
Stability of patch methylation and its impact in regions of transcriptional initiation and elongationQ40023539
Activation of DNA methyltransferase 1 by EBV LMP1 Involves c-Jun NH(2)-terminal kinase signalingQ40192981
Aberrant expression of HOX genes in human invasive breast carcinoma.Q40448756
The Hoxa2 enhancer 2 contains a critical Hoxa2 responsive regulatory elementQ40576442
Matrix metalloproteinase 9 is induced by the Epstein-Barr virus BZLF1 transactivatorQ40903922
Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virusQ40934947
Transient activation of meox1 is an early component of the gene regulatory network downstream of hoxa2Q42707177
Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cellsQ43848237
Plasma Epstein-Barr virus DNA concentration and clearance rate as novel prognostic factors for metastatic nasopharyngeal carcinomaQ45361755
Induction of matrix metalloproteinases by Epstein-Barr virus latent membrane protein 1 isolated from nasopharyngeal carcinoma.Q45399853
Different levels of Hoxa2 are required for particular developmental processesQ48770861
Hoxa2 plays a direct role in murine palate development.Q51928939
Establishment of a cell line (NPC/HK1) from a differentiated squamous carcinoma of the nasopharynx.Q52833887
Genomic profiling of cell-free DNA in blood and bone marrow of prostate cancer patients.Q54658293
Nasopharyngeal carcinomaQ59344163
HOX gene clusters are hotspots of de novo methylation in CpG islands of human lung adenocarcinomasQ74184034
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinomaQ74314745
P433issue11
P407language of work or nameEnglishQ1860
P921main subjecthypermethylationQ106875739
P304page(s)2154-2165
P577publication date2013-11-01
P1433published inOncotargetQ1573155
P1476titleAberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma
P478volume4

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cites work (P2860)
Q35832318By activating matrix metalloproteinase-7, shear stress promotes chondrosarcoma cell motility, invasion and lung colonization.
Q35067875EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy
Q38335029Effects of deranged metabolism on epigenetic changes in cancer
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Q37086039Epstein-Barr virus glycoprotein gH/gL antibodies complement IgA-viral capsid antigen for diagnosis of nasopharyngeal carcinoma
Q41145904Expression of programmed death ligand-1 predicts poor outcome in nasopharyngeal carcinoma
Q35781438Gold nano-particles (AuNPs) carrying anti-EBV-miR-BART7-3p inhibit growth of EBV-positive nasopharyngeal carcinoma
Q55339614Inactivation of the tight junction gene CLDN11 by aberrant hypermethylation modulates tubulins polymerization and promotes cell migration in nasopharyngeal carcinoma.
Q58711257Integrated genomic analyses in PDX model reveal a cyclin-dependent kinase inhibitor Palbociclib as a novel candidate drug for nasopharyngeal carcinoma
Q47405806Serum, plasma and saliva biomarkers for head and neck cancer.
Q34365798Silencing of miRNA-148a by hypermethylation activates the integrin-mediated signaling pathway in nasopharyngeal carcinoma
Q37684072Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity.
Q92527786Study of Promoter Methylation Patterns of HOXA2, HOXA5, and HOXA6 and Its Clinicopathological Characteristics in Colorectal Cancer

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