| scholarly article | Q13442814 |
| P2093 | author name string | Ah-Ng Kong | |
| Guoxiang Shen | |||
| P2860 | cites work | Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region | Q24563505 |
| Isolation of cDNA encoding the human NF-E2 protein | Q24563782 | ||
| Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain | Q24609907 | ||
| Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene | Q24649776 | ||
| The kelch repeat superfamily of proteins: propellers of cell function | Q28140778 | ||
| Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray | Q28202142 | ||
| Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element | Q28214010 | ||
| Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants | Q28218883 | ||
| Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway | Q28238852 | ||
| Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element | Q28240487 | ||
| An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements | Q28244853 | ||
| Protein-DNA interactions at a dioxin-responsive enhancer. Analysis of six bona fide DNA-binding sites for the liganded Ah receptor | Q28263102 | ||
| The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity | Q28296400 | ||
| Nrf2 is essential for protection against acute pulmonary injury in mice | Q28343659 | ||
| An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen | Q28361995 | ||
| Characterization of the 5'-flanking region of the human multidrug resistance protein 2 (MRP2) gene and its regulation in comparison withthe multidrug resistance protein 3 (MRP3) gene | Q28371752 | ||
| Two murine GSTpi genes are arranged in tandem and are differentially expressed | Q28589665 | ||
| Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice | Q29615438 | ||
| Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription | Q29617066 | ||
| Cancer chemoprevention with dietary phytochemicals | Q29617743 | ||
| Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress | Q29617845 | ||
| High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes | Q31783158 | ||
| [The role of NF-E2-related factor 2 in the induction of uridine 5'-diphosphate-glucuronosyltransferase 1A and its isoforms by epigallocatechin gallate in colon cancer cells]. | Q33240190 | ||
| Regulation of glutathione S-transferase Ya subunit gene expression: identification of a unique xenobiotic-responsive element controlling inducible expression by planar aromatic compounds | Q33588263 | ||
| Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis | Q33665840 | ||
| Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter | Q34278223 | ||
| Regulation of Nrf2 transactivation domain activity. The differential effects of mitogen-activated protein kinase cascades and synergistic stimulatory effect of Raf and CREB-binding protein | Q34305832 | ||
| Role of phase 2 enzyme induction in chemoprotection by dithiolethiones | Q34338156 | ||
| Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE). | Q34478999 | ||
| Induction of phase I, II and III drug metabolism/transport by xenobiotics | Q36099291 | ||
| Nrf2 as a novel molecular target for chemoprevention | Q36137929 | ||
| Chemical and molecular regulation of enzymes that detoxify carcinogens | Q36210195 | ||
| Regulation of hepatic transporters by xenobiotic receptors | Q36230593 | ||
| Regulation of Nrf2, NF-kappaB, and AP-1 signaling pathways by chemopreventive agents | Q36342660 | ||
| Nuclear receptor-mediated transcriptional regulation in Phase I, II, and III xenobiotic metabolizing systems | Q36707037 | ||
| Functional antioxidant responsive elements. | Q36772872 | ||
| Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs | Q36795136 | ||
| trans-Stilbene oxide induces expression of genes involved in metabolism and transport in mouse liver via CAR and Nrf2 transcription factors | Q38316272 | ||
| Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in the rat glutathione transferase P gene | Q38343370 | ||
| Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein1 in mouse embryo fibroblasts | Q38349408 | ||
| Role of Nrf2 in the regulation of the Mrp2 (ABCC2) gene | Q40327011 | ||
| Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome | Q40688004 | ||
| Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression | Q40752034 | ||
| Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence | Q42435356 | ||
| Identification of jun-B as third member in human antioxidant response element-nuclear proteins complex | Q42456886 | ||
| Regulation of sulfotransferase enzymes by prototypical microsomal enzyme inducers in mice | Q42521334 | ||
| Transcriptional regulation of the rat NAD(P)H:quinone reductase gene. Identification of regulatory elements controlling basal level expression and inducible expression by planar aromatic compounds and phenolic antioxidants | Q42623620 | ||
| The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes | Q43579706 | ||
| An alternative promoter contributes to tissue- and inducer-specific expression of the rat UDP-glucuronosyltransferase 1A6 gene | Q43662041 | ||
| Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP-glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells | Q44569047 | ||
| Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway: direct cross-talk between phase I and II drug-metabolizing enzymes | Q46404104 | ||
| Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver | Q46440370 | ||
| Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways | Q46513338 | ||
| Modulation of nuclear factor E2-related factor 2-mediated gene expression in mice liver and small intestine by cancer chemopreventive agent curcumin | Q46907979 | ||
| Induction of rat UDP-glucuronosyltransferases in liver and duodenum by microsomal enzyme inducers that activate various transcriptional pathways | Q50092240 | ||
| Role of cytochrome P1-450 in the induction of NAD(P)H:quinone reductase in a murine hepatoma cell line and its mutants. | Q53527232 | ||
| Regulation of CYP2A5 gene by the transcription factor nuclear factor (erythroid-derived 2)-like 2 | Q79782318 | ||
| Induction of hepatic antioxidant enzymes by phenolic acids in rats is accompanied by increased levels of multidrug resistance-associated protein 3 mRNA expression | Q81645237 | ||
| P433 | issue | 7 | |
| P921 | main subject | drug metabolism | Q1124842 |
| P304 | page(s) | 345-355 | |
| P577 | publication date | 2009-10-01 | |
| P1433 | published in | Biopharmaceutics and Drug Disposition | Q15766879 |
| P1476 | title | Nrf2 plays an important role in coordinated regulation of Phase II drug metabolism enzymes and Phase III drug transporters | |
| P478 | volume | 30 |
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| Q28543628 | A novel mathematical model describing adaptive cellular drug metabolism and toxicity in the chemoimmune system |
| Q26852571 | A perspective on dietary phytochemicals and cancer chemoprevention: oxidative stress, nrf2, and epigenomics |
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| Q90477371 | Anti-Inflammatory and Antioxidant Effects of Kelong-Capsule on Testosterone-Induced Benign Prostatic Hyperplasia in Rats |
| Q34344752 | Anti-cancer and potential chemopreventive actions of ginseng by activating Nrf2 (NFE2L2) anti-oxidative stress/anti-inflammatory pathways |
| Q42138790 | Anti-oxidative stress regulator NF-E2-related factor 2 mediates the adaptive induction of antioxidant and detoxifying enzymes by lipid peroxidation metabolite 4-hydroxynonenal |
| Q93048487 | Antioxidant and Adaptative Response Mediated by Nrf2 during Physical Exercise |
| Q37681663 | Antioxidant capacity of phytochemicals and their potential effects on oxidative status in animals - A review |
| Q38203281 | Cancer chemoprevention by traditional chinese herbal medicine and dietary phytochemicals: targeting nrf2-mediated oxidative stress/anti-inflammatory responses, epigenetics, and cancer stem cells. |
| Q37120909 | Drug metabolism alterations in nonalcoholic fatty liver disease |
| Q28383476 | Dual TNFα-induced effects on NRF2 mediated antioxidant defence in astrocyte-rich cultures: role of protein kinase activation |
| Q49127325 | Effects of Phenobarbital on Expression of UDP-Glucuronosyltransferase 1a6 and 1a7 in Rat Brain |
| Q36666323 | Enhanced phase II detoxification contributes to beneficial effects of dietary restriction as revealed by multi-platform metabolomics studies |
| Q92534990 | Environmental Electrophile-Mediated Toxicity in Mice Lacking Nrf2, CSE, or Both |
| Q37969214 | Environmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics |
| Q90083998 | GSTA4 mediates reduction of cisplatin ototoxicity in female mice |
| Q34448767 | Genetic polymorphism in the NRF2 gene as a prognosis marker for cancer chemotherapy |
| Q49195198 | Glutathione homeostasis is significantly altered by quercetin via the Keap1/Nrf2 and MAPK signaling pathways in rats |
| Q28250453 | Identification of a functional antioxidant response element within the eighth intron of the human ABCC3 gene |
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| Q39360172 | Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2. |
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| Q55450574 | Membrane Remodeling as a Key Player of the Hepatotoxicity Induced by Co-Exposure to Benzo[a]pyrene and Ethanol of Obese Zebrafish Larvae. |
| Q28395388 | Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice |
| Q61812025 | Mg-supplementation attenuated lipogenic and oxidative/nitrosative gene expression caused by Combination Antiretroviral Therapy (cART) in HIV-1-transgenic rats |
| Q35171243 | MicroRNA expression is differentially altered by xenobiotic drugs in different human cell lines. |
| Q36991523 | Molecular mechanisms underlying chemical liver injury |
| Q48174531 | Natural Dietary Pigments: Potential Mediators against Hepatic Damage Induced by Over-The-Counter Non-Steroidal Anti-Inflammatory and Analgesic Drugs. |
| Q47404871 | Natural polyphenol chlorogenic acid protects against acetaminophen-induced hepatotoxicity by activating ERK/Nrf2 antioxidative pathway |
| Q39246209 | Nrf2 Transcription Factor Can Directly Regulate mTOR: LINKING CYTOPROTECTIVE GENE EXPRESSION TO A MAJOR METABOLIC REGULATOR THAT GENERATES REDOX ACTIVITY. |
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| Q36301764 | Nuclear factor-erythroid 2-related factor 2 as a chemopreventive target in colorectal cancer. |
| Q28388352 | Persistent polar depletion of stratospheric ozone and emergent mechanisms of ultraviolet radiation-mediated health dysregulation |
| Q39528016 | Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates. |
| Q41828997 | Pharmacokinetics of dietary cancer chemopreventive compound dibenzoylmethane in rats and the impact of nanoemulsion and genetic knockout of Nrf2 on its disposition |
| Q36329743 | Phorbaketal A, Isolated from the Marine Sponge Phorbas sp., Exerts Its Anti-Inflammatory Effects via NF-κB Inhibition and Heme Oxygenase-1 Activation in Lipopolysaccharide-Stimulated Macrophages |
| Q46685516 | Protective effect of rutin against brain injury induced by acrylamide or gamma radiation: role of PI3K/AKT/GSK-3β/NRF-2 signalling pathway |
| Q57212655 | Reestablishment of ischemia-reperfusion liver injury by N-acetylcysteine administration prior to a preconditioning iron protocol |
| Q39617672 | Regulation of KEAP1 expression by promoter methylation in malignant gliomas and association with patient's outcome |
| Q64100479 | Regulation of P-glycoprotein by Bajijiasu in vitro and in vivo by activating the Nrf2-mediated signalling pathway |
| Q37422667 | Role of constitutive androstane receptor in Toll-like receptor-mediated regulation of gene expression of hepatic drug-metabolizing enzymes and transporters |
| Q38097092 | Role of microRNAs in the regulation of drug metabolism and disposition genes in diabetes and liver disease |
| Q34989327 | SNP (-617C>A) in ARE-like loci of the NRF2 gene: a new biomarker for prognosis of lung adenocarcinoma in Japanese non-smoking women |
| Q28385056 | Schisandra chinensis regulates drug metabolizing enzymes and drug transporters via activation of Nrf2-mediated signaling pathway |
| Q39083998 | Subtoxic and toxic concentrations of benzene and toluene induce Nrf2-mediated antioxidative stress response and affect the central carbon metabolism in lung epithelial cells A549. |
| Q51498602 | Sulforaphane Regulates NFE2L2/Nrf2-Dependent Xenobiotic Metabolism Phase II and Phase III Enzymes Differently in Human Colorectal Cancer and Untransformed Epithelial Colon Cells. |
| Q47122129 | The Ethanol Extract of Licorice (Glycyrrhiza uralensis) Protects against Triptolide-Induced Oxidative Stress through Activation of Nrf2. |
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