Transcriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development

scientific article published on 07 December 2016

Transcriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/SREP38665
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/srep38665
P932PMC publication ID5141430
P698PubMed publication ID27924849

P50authorKelvin Y KwanQ57014684
P2093author name stringYing Li
Martin Grumet
Li Cai
Evangeline Tzatzalos
P2860cites workDelta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise processQ57315061
Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity.Q37288224
Cux2 functions downstream of Notch signaling to regulate dorsal interneuron formation in the spinal cordQ37311681
Asymmetric activation of Dll4-Notch signaling by Foxn4 and proneural factors activates BMP/TGFβ signaling to specify V2b interneurons in the spinal cordQ37398499
Notch in the vertebrate nervous system: an old dog with new tricksQ37850550
Neural stem cells in the adult spinal cordQ38078736
Attenuation of green fluorescent protein half-life in mammalian cellsQ40909794
Diversity and pattern in the developing spinal cordQ41191457
SnapShot: spinal cord developmentQ42871471
Notch signaling is required to maintain all neural stem cell populations--irrespective of spatial or temporal nicheQ46969252
Different combinations of Notch ligands and receptors regulate V2 interneuron progenitor proliferation and V2a/V2b cell fate determinationQ47073276
Active 3-D microscaffold system with fluid perfusion for culturing in vitro neuronal networksQ48226833
Molecular mapping of the origin of postnatal spinal cord ependymal cells: evidence that adult ependymal cells are derived from Nkx6.1+ ventral neural progenitor cells.Q48409266
Notch1 signaling influences v2 interneuron and motor neuron development in the spinal cord.Q48633245
Loss of notch activity in the developing central nervous system leads to increased cell death.Q48633296
Introduction of DNA into chick embryos by in ovo electroporation.Q52136080
A high-resolution anatomical atlas of the transcriptome in the mouse embryoQ21145782
A family of mammalian Fringe genes implicated in boundary determination and the Notch pathwayQ24310459
A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor poolQ24338675
The astrocyte odysseyQ24654727
Spinal cord injury reveals multilineage differentiation of ependymal cellsQ27333067
Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalonQ28589549
Gsh-1: a novel murine homeobox gene expressed in the central nervous systemQ28591303
Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneuronsQ28591585
A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tubeQ28593188
Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cordQ28750357
A series of normal stages in the development of the chick embryoQ29037347
TRANSFAC: an integrated system for gene expression regulationQ29614502
Neuronal specification in the spinal cord: inductive signals and transcriptional codesQ29616039
In vivo enhancer analysis of human conserved non-coding sequencesQ29616554
Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse developmentQ30996868
Nuclear Notch1 signaling and the regulation of dendritic developmentQ33884395
Regulation of the neural patterning activity of sonic hedgehog by secreted BMP inhibitors expressed by notochord and somites.Q33922547
Origin of new glial cells in intact and injured adult spinal cord.Q34141207
In vivo characterization of a vertebrate ultraconserved enhancerQ34417560
Identification of a neural stem cell in the adult mammalian central nervous systemQ34492720
Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fatesQ35202057
A direct fate exclusion mechanism by Sonic hedgehog-regulated transcriptional repressorsQ36245078
A cis-element in the Notch1 locus is involved in the regulation of gene expression in interneuron progenitors.Q36456214
The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cordQ36744039
Fate of endogenous stem/progenitor cells following spinal cord injuryQ36908154
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)38665
P577publication date2016-12-07
P1433published inScientific ReportsQ2261792
P1476titleTranscriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development
P478volume6

Reverse relations

cites work (P2860)
Q100635976CHD7 promotes neural progenitor differentiation in embryonic stem cells via altered chromatin accessibility and nascent gene expression
Q90360417Engineering advanced neural tissue constructs to mitigate acute cerebral inflammation after brain transplantation in rats
Q43673069Radial Extracorporeal Shock Wave Therapy Enhances the Proliferation and Differentiation of Neural Stem Cells by Notch, PI3K/AKT, and Wnt/β-catenin Signaling
Q93046793Restoring Motor Neurons in Spinal Cord Injury With Induced Pluripotent Stem Cells

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