Bendamustine in B-Cell Malignancies: The New 46-Year-Old Kid on the Block

scientific article published on December 2009

Bendamustine in B-Cell Malignancies: The New 46-Year-Old Kid on the Block is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/1078-0432.CCR-08-3041
P932PMC publication ID2795094
P698PubMed publication ID19996200
P5875ResearchGate publication ID40483031

P2093author name stringVarsha Gandhi
Jan A Burger
P2860cites workFludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemiaQ28140129
Bendamustine monotherapy in advanced and refractory chronic lymphocytic leukemiaQ32019548
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Bendamustine plus rituximab is effective and has a favorable toxicity profile in the treatment of mantle cell and low-grade non-Hodgkin's lymphomaQ33366403
Fludarabine plus cyclophosphamide versus fludarabine alone in first-line therapy of younger patients with chronic lymphocytic leukemiaQ33368885
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Phase II multicenter study of bendamustine plus rituximab in patients with relapsed indolent B-cell and mantle cell non-Hodgkin's lymphomaQ33380352
Phase III randomized study of bendamustine compared with chlorambucil in previously untreated patients with chronic lymphocytic leukemiaQ33385646
Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemiaQ34402999
New treatment options have changed the survival of patients with follicular lymphomaQ34561857
Bendamustine (Treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents.Q34586659
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Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemiaQ37634897
First-line therapy with fludarabine compared with chlorambucil does not result in a major benefit for elderly patients with advanced chronic lymphocytic leukemiaQ38380183
Characterization of two phase I metabolites of bendamustine in human liver microsomes and in cancer patients treated with bendamustine hydrochlorideQ40234705
Weekly administration of bendamustine: a phase I study in patients with advanced progressive solid tumoursQ40616659
Treatment of multiple myeloma with a new cytostatic agent: gamma-l-methyl-5-bis-(beta-chlorethyl)-amino-benzimidazolyl-(2)-butyric acid hydrochlorideQ43411162
Bendamustine in the treatment of chronic lymphocytic leukemia: results and future perspectivesQ44096414
High rates of long-lasting remissions after 5-day bendamustine chemotherapy cycles in pre-treated low-grade non-Hodgkin's-lymphomasQ44233737
Frontline therapy with rituximab added to the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly improves the outcome for patients with advanced-stage follicular lymphoma compared with therapy with CHOP alQ46669969
Phase-I/II study to evaluate dose limiting toxicity, maximum tolerated dose, and tolerability of bendamustine HCl in pre-treated patients with B-chronic lymphocytic leukaemia (Binet stages B and C) requiring therapy.Q51831972
[Clinical proof is the decisive terrain. The history of alkylating agents].Q52933783
Efficacy and toxicity of bendamustine in patients with relapsed low-grade non-Hodgkin's lymphomas.Q53991694
[Pharmacokinetics of bendamustin (Cytostasan) in B6D2F1-mice]Q67870047
Investigation of cross-link formation in DNA by the alkylating cytostatica IMET 3106, 3393 and 3943Q69379614
On the methodology of the determination of alkylating activities of nitrogen mustards with nitrobenzylpyridine (NBP) in biological material (author's transl)Q70984808
Rituximab maintenance improves clinical outcome of relapsed/resistant follicular non-Hodgkin lymphoma in patients both with and without rituximab during induction: results of a prospective randomized phase 3 intergroup trialQ80011702
Efficacy of bendamustine in patients with relapsed or refractory chronic lymphocytic leukemia: results of a phase I/II study of the German CLL Study GroupQ81340591
[The pharmacokinetics of bendamustine (Cytostasane) in humans]Q93687483
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectbendamustineQ425745
P304page(s)7456-7461
P577publication date2009-12-01
P1433published inClinical Cancer ResearchQ332253
P1476titleBendamustine in B-Cell Malignancies: The New 46-Year-Old Kid on the Block
P478volume15

Reverse relations

cites work (P2860)
Q33591830A phase I-II trial of fludarabine, bendamustine and rituximab (FBR) in previously treated patients with CLL.
Q38260135Combination of Pim kinase inhibitor SGI-1776 and bendamustine in B-cell lymphoma
Q43584641Efficacy and safety of bendamustine for the treatment of patients with recurring Hodgkin lymphoma.
Q33749652Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells
Q92691466High-dose bendamustine and melphalan conditioning for autologous stem cell transplantation for patients with multiple myeloma
Q37725415Idelalisib and bendamustine combination is synergistic and increases DNA damage response in chronic lymphocytic leukemia cells
Q35958056Pharmacological and Protein Profiling Suggests Venetoclax (ABT-199) as Optimal Partner with Ibrutinib in Chronic Lymphocytic Leukemia
Q53670141Renal human organic anion transporter 3 increases the susceptibility of lymphoma cells to bendamustine uptake.
Q37659071Update on therapy of chronic lymphocytic leukemia

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