Inhalation delivery of Telmisartan enhances intratumoral distribution of nanoparticles in lung cancer models

scientific article published on 07 July 2013

Inhalation delivery of Telmisartan enhances intratumoral distribution of nanoparticles in lung cancer models is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JCONREL.2013.06.036
P932PMC publication ID3895504
P698PubMed publication ID23838154

P2093author name stringApurva R Patel
Chandraiah Godugu
Mandip Singh
Ravi Doddapaneni
Srujan Marepally
Tanise Jackson
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TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma.Q36339786
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Telmisartan counteracts TGF-β1 induced epithelial-to-mesenchymal transition via PPAR-γ in human proximal tubule epithelial cellsQ39285206
Angiotensin-(1-7) attenuates metastatic prostate cancer and reduces osteoclastogenesisQ39340215
Angiotensin-(1-7) reduces proliferation and angiogenesis of human prostate cancer xenografts with a decrease in angiogenic factors and an increase in sFlt-1.Q39340234
Tumor-homing multifunctional nanoparticles for cancer theragnosis: Simultaneous diagnosis, drug delivery, and therapeutic monitoringQ39713271
The effect of Telmisartan on collagen biosynthesis depends on the status of estrogen activation in breast cancer cells.Q39769660
Regulation of prostate cancer cell growth and PSA expression by angiotensin II receptor blocker with peroxisome proliferator-activated receptor gamma ligand like actionQ40144286
Angiotensin-(1-7) inhibits growth of human lung adenocarcinoma xenografts in nude mice through a reduction in cyclooxygenase-2.Q40158311
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Dasatinib reverses cancer-associated fibroblasts (CAFs) from primary lung carcinomas to a phenotype comparable to that of normal fibroblastsQ41887621
Modulation of transforming growth factor-β signaling and extracellular matrix production in myxomatous mitral valves by angiotensin II receptor blockersQ42512492
Telmisartan attenuates oxidative stress and renal fibrosis in streptozotocin induced diabetic mice with the alteration of angiotensin-(1-7) mas receptor expression associated with its PPAR-γ agonist action.Q42747102
Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vectorQ45419303
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on sizeQ47348224
Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors.Q54650279
TGF beta-1 regulation of VEGF production by breast cancer cellsQ73992257
Telmisartan, a unique ARB, improves left ventricular remodeling of infarcted heart by activating PPAR gammaQ83611006
AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonistQ24652842
Cancer statistics, 2012Q27860574
Therapeutic nanoparticles for drug delivery in cancerQ28271255
Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorshipQ28278682
Increase in tumour permeability following TGF-beta type I receptor-inhibitor treatment observed by dynamic contrast-enhanced MRIQ28749643
Peroxisome proliferator-activated receptor-gamma activation inhibits tumor metastasis by antagonizing Smad3-mediated epithelial-mesenchymal transitionQ30498249
Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancerQ30499935
Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic miceQ33534042
Angiotensin-receptor blockade and risk of cancer: meta-analysis of randomised controlled trialsQ33803829
Telmisartan as a peroxisome proliferator-activated receptor-γ ligand is a new target in the treatment of human renal cell carcinomaQ33865772
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activityQ33976477
Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFβ activationQ34163525
Angiotensin II facilitates breast cancer cell migration and metastasisQ34247434
Over-expression of angiotensin II type 2 receptor gene induces cell death in lung adenocarcinoma cellsQ34280097
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectlung cancerQ47912
nanoparticleQ61231
P304page(s)86-95
P577publication date2013-07-07
P1433published inJournal of Controlled ReleaseQ6295046
P1476titleInhalation delivery of Telmisartan enhances intratumoral distribution of nanoparticles in lung cancer models
P478volume172

Reverse relations

cites work (P2860)
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