Grape seed extract dose-responsively decreases disease severity in a rat model of mucositis; concomitantly enhancing chemotherapeutic effectiveness in colon cancer cells.

scientific article published on 21 January 2014

Grape seed extract dose-responsively decreases disease severity in a rat model of mucositis; concomitantly enhancing chemotherapeutic effectiveness in colon cancer cells. is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...985184C
P356DOI10.1371/JOURNAL.PONE.0085184
P932PMC publication ID3897410
P698PubMed publication ID24465501
P5875ResearchGate publication ID259919781

P50authorSusan BastianQ73348954
P2093author name stringGordon Stanley Howarth
Ker Yeaw Cheah
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Gastrointestinal dysmotility in 5-fluorouracil-induced intestinal mucositis outlasts inflammatory process resolutionQ46715695
Modulatory effect of grape-seed procyanidins on local and systemic inflammation in diet-induced obesity ratsQ60197862
Milk growth factors enriched from cheese whey ameliorate intestinal damage by methotrexate when administered orally to ratsQ71656276
Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster modelsQ72397450
Oxygen free radical scavenging abilities of vitamins C and E, and a grape seed proanthocyanidin extract in vitroQ73197339
A novel non-invasive biomarker for assessment of small intestinal mucositis in children with cancer undergoing chemotherapyQ79167320
Probiotic effects on 5-fluorouracil-induced mucositis assessed by the sucrose breath test in ratsQ79611039
Emerging drugs for chemotherapy-induced mucositisQ81916510
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Oligomeric proanthocyanidin complexes: history, structure, and phytopharmaceutical applicationsQ28142067
Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cellsQ28286398
Irinotecan changes gene expression in the small intestine of the rat with breast cancerQ28577612
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Oral and intestinal mucositis — causes and possible treatmentsQ33195001
Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cellsQ33632727
Validation of a new scoring system for the assessment of clinical trial research of oral mucositis induced by radiation or chemotherapy. Mucositis Study GroupQ33862023
Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c releaseQ33962301
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Grape seed extract reduces the severity of selected disease markers in the proximal colon of dextran sulphate sodium-induced colitis in ratsQ39521803
Apoptosis-inducing factor and caspase-dependent apoptotic pathways triggered by different grape seed extracts on human colon cancer cell line Caco-2.Q39694337
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Grape seed extract protects IEC-6 cells from chemotherapy-induced cytotoxicity and improves parameters of small intestinal mucositis in rats with experimentally-induced mucositisQ39869735
Proanthocyanidin from grape seeds inactivates the PI3-kinase/PKB pathway and induces apoptosis in a colon cancer cell lineQ40070483
Increased functional expression of P-glycoprotein in Caco-2 TC7 cells exposed long-term to cadmium.Q40436177
Effect of an omega-3 fatty acid containing lipid emulsion alone and in combination with 5-fluorouracil (5-FU) on growth of the colon cancer cell line Caco-2.Q40607777
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcolon cancerQ18555025
chemotherapyQ974135
P304page(s)e85184
P577publication date2014-01-21
P1433published inPLOS OneQ564954
P1476titleGrape seed extract dose-responsively decreases disease severity in a rat model of mucositis; concomitantly enhancing chemotherapeutic effectiveness in colon cancer cells
P478volume9