| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2014PLoSO...986872L |
| P356 | DOI | 10.1371/JOURNAL.PONE.0086872 |
| P932 | PMC publication ID | 3900676 |
| P698 | PubMed publication ID | 24466275 |
| P5875 | ResearchGate publication ID | 259920410 |
| P50 | author | John M. Luk | Q42935545 |
| P2093 | author name string | Zhi Xu | |
| Nikki P Lee | |||
| Jinfei Chen | |||
| Kwong-Fai Wong | |||
| Ronnie T Poon | |||
| Angela M Liu | |||
| Felix H Shek | |||
| P2860 | cites work | Proliferative activity in hepatocellular carcinoma is closely correlated with glucose metabolism but not angiogenesis. | Q54611728 |
| Identification of small molecule inhibitors of pyruvate kinase M2 | Q22001512 | ||
| Global cancer statistics | Q22241238 | ||
| microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma | Q24595141 | ||
| Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth | Q24603549 | ||
| Understanding the Warburg effect: the metabolic requirements of cell proliferation | Q24604760 | ||
| MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib | Q24655048 | ||
| On the Origin of Cancer Cells | Q27861025 | ||
| The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth | Q29547680 | ||
| Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma | Q33611696 | ||
| 2-Oxo-N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase | Q34035183 | ||
| Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation | Q34091042 | ||
| MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties. | Q34103666 | ||
| Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth. | Q34195003 | ||
| Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses | Q34230044 | ||
| MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma | Q34964774 | ||
| Two-tiered approach identifies a network of cancer and liver disease-related genes regulated by miR-122. | Q34979073 | ||
| Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties | Q34993023 | ||
| Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma | Q35893965 | ||
| AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma. | Q35899490 | ||
| MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis | Q36129123 | ||
| PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis | Q36199783 | ||
| Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer | Q38012878 | ||
| HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer | Q39763266 | ||
| Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth | Q39773538 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hepatocellular carcinoma | Q1148337 |
| P304 | page(s) | e86872 | |
| P577 | publication date | 2014-01-23 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | miR-122 targets pyruvate kinase M2 and affects metabolism of hepatocellular carcinoma | |
| P478 | volume | 9 |
| Q35883006 | Association between microRNA polymorphisms and papillary thyroid cancer susceptibility |
| Q50668089 | CHIP/Stub1 regulates the Warburg effect by promoting degradation of PKM2 in ovarian carcinoma. |
| Q38208982 | Canonical and new generation anticancer drugs also target energy metabolism. |
| Q37086191 | Chronic inflammation contributes to the development of hepatocellular carcinoma by decreasing miR-122 levels |
| Q41597501 | Co-expression of PKM2 and TRIM35 predicts survival and recurrence in hepatocellular carcinoma. |
| Q55404931 | Co-expression of PKM2 and TRIM35 predicts survival and recurrence in hepatocellular carcinoma. |
| Q38722204 | Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma |
| Q60917019 | Determining consistent prognostic biomarkers of overall survival and vascular invasion in hepatocellular carcinoma |
| Q38783947 | Differential expression of genes related to glucose metabolism in domesticated pigs and wild boar |
| Q59329634 | Effects of PKM2 on global metabolic changes and prognosis in hepatocellular carcinoma: from gene expression to drug discovery |
| Q47568010 | Effects of sorafenib on lung metastasis in rats with hepatocellular carcinoma: the role of microRNAs |
| Q40240007 | GLUT3 and PKM2 regulate OCT4 expression and support the hypoxic culture of human embryonic stem cells. |
| Q50002028 | Identification of Key Pathways and Genes in the Dynamic Progression of HCC Based on WGCNA. |
| Q46605748 | Inhibition of breast cancer cell proliferation and tumorigenesis by long non-coding RNA RPPH1 down-regulation of miR-122 expression |
| Q28079138 | Involvement of inflammation and its related microRNAs in hepatocellular carcinoma |
| Q60948600 | Long Non-Coding RNAs as Mediators of Tumor Microenvironment and Liver Cancer Cell Communication |
| Q33709646 | MiR-let-7a inhibits cell proliferation, migration, and invasion by down-regulating PKM2 in cervical cancer |
| Q41208796 | MicroRNA Regulation of Glycolytic Metabolism in Glioblastoma. |
| Q39189133 | MicroRNA regulation and analytical methods in cancer cell metabolism |
| Q38845548 | MicroRNA-122 affects cell aggressiveness and apoptosis by targeting PKM2 in human hepatocellular carcinoma |
| Q64228210 | MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway |
| Q26780451 | MicroRNAs Regulate Mitochondrial Function in Cerebral Ischemia-Reperfusion Injury |
| Q26745980 | MicroRNAs and oncogenic transcriptional regulatory networks controlling metabolic reprogramming in cancers |
| Q92541923 | MicroRNAs in Tumor Cell Metabolism: Roles and Therapeutic Opportunities |
| Q36503853 | Microtargeting cancer metabolism: opening new therapeutic windows based on lipid metabolism |
| Q60049293 | Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture |
| Q41544729 | Molecular Pathogenesis of Hepatocellular Carcinoma. |
| Q33702300 | Mutual Regulation of MiR-199a-5p and HIF-1α Modulates the Warburg Effect in Hepatocellular Carcinoma. |
| Q38932383 | Oleanolic acid suppresses the proliferation of lung carcinoma cells by miR-122/Cyclin G1/MEF2D axis |
| Q47153446 | PKM2 in carcinogenesis and oncotherapy |
| Q36023978 | Phage display library selection of a hypoxia-binding scFv antibody for liver cancer metabolic marker discovery |
| Q52691292 | Posttranslational Modifications of Pyruvate Kinase M2: Tweaks that Benefit Cancer. |
| Q35170154 | Proteome mapping of epidermal growth factor induced hepatocellular carcinomas identifies novel cell metabolism targets and mitogen activated protein kinase signalling events |
| Q27005722 | Pyruvate kinase M2 at a glance |
| Q28076454 | Reprogramming of glucose metabolism in hepatocellular carcinoma: Progress and prospects |
| Q49587519 | Serum microRNA-193b as a promising biomarker for prediction of chemoradiation sensitivity in esophageal squamous cell carcinoma patients |
| Q37645670 | Shortcuts to a functional adipose tissue: The role of small non-coding RNAs. |
| Q38852443 | Single-Vehicular Delivery of Antagomir and Small Molecules to Inhibit miR-122 Function in Hepatocellular Carcinoma Cells by using "Smart" Mesoporous Silica Nanoparticles |
| Q55401749 | Small but Heavy Role: MicroRNAs in Hepatocellular Carcinoma Progression. |
| Q34777160 | Switching of pyruvate kinase isoform L to M2 promotes metabolic reprogramming in hepatocarcinogenesis |
| Q92151502 | The contribution of miR-122 to the innate immunity by regulating toll-like receptor 4 in hepatoma cells |
| Q92480934 | The functions and clinical application potential of exosomes derived from adipose mesenchymal stem cells: a comprehensive review |
| Q92889066 | The miR-873/NDFIP1 axis promotes hepatocellular carcinoma growth and metastasis through the AKT/mTOR-mediated Warburg effect |
| Q46488114 | The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis |
| Q55387493 | The role of miR-122 in the dysregulation of glucose-6-phosphate dehydrogenase (G6PD) expression in hepatocellular cancer. |
| Q39072215 | The role of microRNAs in hepatocyte metabolism and hepatitis B virus replication |
| Q38272241 | Warburg meets non-coding RNAs: the emerging role of ncRNA in regulating the glucose metabolism of cancer cells |
| Q50284067 | miR-122 inhibits cancer cell malignancy by targeting PKM2 in gallbladder carcinoma |
| Q37144041 | miR-144 reverses chemoresistance of hepatocellular carcinoma cell lines by targeting Nrf2-dependent antioxidant pathway |
| Q54196607 | miR-144 suppresses the proliferation and metastasis of hepatocellular carcinoma by targeting E2F3. |
| Q54196604 | miR-24 promotes the proliferation and invasion of HCC cells by targeting SOX7. |
| Q37376524 | miR-592/WSB1/HIF-1α axis inhibits glycolytic metabolism to decrease hepatocellular carcinoma growth. |
| Q50064930 | miRNA in tumour metabolism and why could it be the preferred pathway for energy reprograming |
| Q64997729 | rs61991156 in miR-379 is associated with low capability of glycolysis of gastric cancer by enhanced regulation of PKM2. |
Search more.