Knowledge-Guided Bioinformatics Model for Identifying Autism Spectrum Disorder Diagnostic MicroRNA Biomarkers

scientific article published on 21 December 2016

Knowledge-Guided Bioinformatics Model for Identifying Autism Spectrum Disorder Diagnostic MicroRNA Biomarkers is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1046713035
P356DOI10.1038/SREP39663
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/srep39663
P932PMC publication ID5175196
P698PubMed publication ID28000768

P2093author name stringLuonan Chen
Li Shen
Bairong Shen
Yuxin Lin
Xuye Yuan
Zhandong Sun
P2860cites workRett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2Q22337290
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Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder.Q38804936
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starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq dataQ30705717
Support vector machine model of developmental brain gene expression data for prioritization of Autism risk gene candidatesQ31120587
Genetic evidence implicating multiple genes in the MET receptor tyrosine kinase pathway in autism spectrum disorderQ33429117
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Autism and increased paternal age related changes in global levels of gene expression regulationQ33838419
Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell linesQ33865755
Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brainQ34017168
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Identification of novel microRNA regulatory pathways associated with heterogeneous prostate cancer.Q35098669
Assessing the impact of copy number variants on miRNA genes in autism by Monte Carlo simulationQ35130993
International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1-4, the receptors for relaxin family peptides.Q35383835
Mining the 3'UTR of autism-implicated genes for SNPs perturbing microRNA regulationQ35543490
TarBase 6.0: capturing the exponential growth of miRNA targets with experimental supportQ35631073
Investigation of Gene Regulatory Networks Associated with Autism Spectrum Disorder Based on MiRNA Expression in ChinaQ35659845
Aberrant T-lymphocyte development and function in mice overexpressing human soluble amyloid precursor protein-α: implications for autism.Q35787737
Brain-derived neurotrophic factor and neuropsychiatric disordersQ35847085
Salivary miRNA profiles identify children with autism spectrum disorder, correlate with adaptive behavior, and implicate ASD candidate genes involved in neurodevelopmentQ35997185
Engrailed-2 (En2) deletion produces multiple neurodevelopmental defects in monoamine systems, forebrain structures and neurogenesis and behaviorQ36089383
MicroRNA biomarker identification for pediatric acute myeloid leukemia based on a novel bioinformatics model.Q36413478
Profiling olfactory stem cells from living patients identifies miRNAs relevant for autism pathophysiologyQ36443544
Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic networkQ36685517
MicroRNA-29a Is a Candidate Biomarker for Alzheimer's Disease in Cell-Free Cerebrospinal Fluid.Q36994237
The autism-associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrainQ37022643
Clear cell renal cell carcinoma associated microRNA expression signatures identified by an integrated bioinformatics analysisQ37088462
Dynamic gene and protein expression patterns of the autism-associated met receptor tyrosine kinase in the developing mouse forebrainQ37110137
Genes showing altered expression in the medial preoptic area in the highly social maternal phenotype are related to autism and other disorders with social deficitsQ37531777
miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactionsQ37661923
Evolving role of MeCP2 in Rett syndrome and autismQ37754018
The canonical Wnt signaling pathway in autismQ38173455
Brain-derived neurotrophic factor and Rett syndromeQ38199423
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that useslimmaQ112236343
P407language of work or nameEnglishQ1860
P921main subjectautismQ38404
bioinformaticsQ128570
microRNAQ310899
biomarkerQ864574
autism spectrum disorderQ1436063
diagnosisQ16644043
P304page(s)39663
P577publication date2016-12-21
P1433published inScientific ReportsQ2261792
P1476titleKnowledge-Guided Bioinformatics Model for Identifying Autism Spectrum Disorder Diagnostic MicroRNA Biomarkers
P478volume6

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cites work (P2860)
Q46847129Biomarker MicroRNAs for Diagnosis of Oral Squamous Cell Carcinoma Identified Based on Gene Expression Data and MicroRNA-mRNA Network Analysis.
Q55254366CBD: a biomarker database for colorectal cancer.
Q45943371Computer-aided biomarker discovery for precision medicine: data resources, models and applications.
Q33862388Diagnostic MicroRNA Biomarker Discovery for Non-Small-Cell Lung Cancer Adenocarcinoma by Integrative Bioinformatics Analysis.
Q47668612Interactions Between Genetics, Lifestyle, and Environmental Factors for Healthcare
Q64963896MicroRNA-153 promotes brain-derived neurotrophic factor and hippocampal neuron proliferation to alleviate autism symptoms through inhibition of JAK-STAT pathway by LEPR.
Q47187211Systems Health: A Transition from Disease Management Toward Health Promotion
Q96950520Systems biology comprehensive analysis on breast cancer for identification of key gene modules and genes associated with TNM-based clinical stages
Q55513254Translational Bioinformatics for Cholangiocarcinoma: Opportunities and Challenges.

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