Co-Administration of Lipid Nanoparticles and Sub-Unit Vaccine Antigens Is Required for Increase in Antigen-Specific Immune Responses in Mice

scientific article published on 06 December 2016

Co-Administration of Lipid Nanoparticles and Sub-Unit Vaccine Antigens Is Required for Increase in Antigen-Specific Immune Responses in Mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/VACCINES4040047
P932PMC publication ID5192367
P698PubMed publication ID27929422

P50authorKara CoxQ88400972
Gokul SwaminathanQ117535977
P2093author name stringAndrew J Bett
Danilo R Casimiro
Elizabeth A Thoryk
Steven Meschino
Marian Gindy
P2860cites workEngineering synthetic vaccines using cues from natural immunityQ38154804
A novel lipid nanoparticle adjuvant significantly enhances B cell and T cell responses to sub-unit vaccine antigensQ38944133
AS04, an aluminum salt- and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunityQ39782280
CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responsesQ41736997
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Immunogenicity of a reduced-dose whole killed rabies vaccine is significantly enhanced by ISCOMATRIX™ adjuvant, Merck amorphous aluminum hydroxylphosphate sulfate (MAA) or a synthetic TLR9 agonist in rhesus macaquesQ42276948
Targeted delivery of TLR ligands to human and mouse dendritic cells strongly enhances adjuvanticityQ43638130
Quil A-lipid powder formulations releasing ISCOMs and related colloidal structures upon hydrationQ45264739
Influences of excipients on in vitro release and in vivo performance of tetanus toxoid loaded polymer particlesQ45289233
Stabilization of Ostwald ripening in low molecular weight amino lipid nanoparticles for systemic delivery of siRNA therapeuticsQ47430410
The need for IgG2c specific antiserum when isotyping antibodies from C57BL/6 and NOD mice.Q47809273
Quantification of antigen specific CD8+ T cells using an ELISPOT assayQ47999428
Mechanism of immunopotentiation by aluminum-containing adjuvants elucidated by the relationship between antigen retention at the inoculation site and the immune response.Q50560920
Methods of effective conjugation of antigens to nanoparticles as non-inflammatory vaccine carriers.Q51019872
A comparative study of cationic liposome and niosome-based adjuvant systems for protein subunit vaccines: characterisation, environmental scanning electron microscopy and immunisation studies in miceQ58827824
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Effect of the strength of adsorption of hepatitis B surface antigen to aluminum hydroxide adjuvant on the immune responseQ82910116
Polyelectrolyte Multilayers Assembled Entirely from Immune Signals on Gold Nanoparticle Templates Promote Antigen-Specific T Cell ResponseQ85278186
Adjuvants: Classification, Modus Operandi, and LicensingQ26747586
Nanoparticle Drug Delivery Systems Designed to Improve Cancer Vaccines and ImmunotherapyQ26782566
Molecular signatures of vaccine adjuvantsQ26865514
A Tetravalent Sub-unit Dengue Vaccine Formulated with Ionizable Cationic Lipid Nanoparticle induces Significant Immune Responses in Rodents and Non-Human PrimatesQ27116692
Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonistQ30573156
Lipid-polymer hybrid nanoparticles as a new generation therapeutic delivery platform: a reviewQ30656373
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Antigen depot is not required for alum adjuvanticityQ34235031
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A novel hepatitis B vaccine containing Advax™, a polysaccharide adjuvant derived from delta inulin, induces robust humoral and cellular immunity with minimal reactogenicity in preclinical testingQ36711264
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P577publication date2016-12-06
P1433published inVaccinesQ27725508
P1476titleCo-Administration of Lipid Nanoparticles and Sub-Unit Vaccine Antigens Is Required for Increase in Antigen-Specific Immune Responses in Mice
P478volume4