Strain-specific innate immune signaling pathways determine malaria parasitemia dynamics and host mortality

scientific article published on 13 January 2014

Strain-specific innate immune signaling pathways determine malaria parasitemia dynamics and host mortality is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PNAS..111E.511W
P356DOI10.1073/PNAS.1316467111
P932PMC publication ID3910569
P698PubMed publication ID24474800
P5875ResearchGate publication ID259961149

P50authorCarole A LongQ66908908
Marlene S. OrandleQ106267006
Xinzhuan SuQ37374247
P2093author name stringJian Wu
Weishi Yu
Jian Li
John E Coligan
Xiao Yu
Linjie Tian
Mingjun Wang
Sittiporn Pattaradilokrat
Timothy G Myers
Chen-Feng Qi
Rongfu Wang
Yanwei Qi
Sethu C Nair
Steve P Crampton
Amir E Zeituni
Silvia M Bolland
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Splenic red pulp macrophages produce type I interferons as early sentinels of malaria infection but are dispensable for controlQ27312553
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Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNAQ28118718
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Murine cerebral malaria development is independent of toll-like receptor signalingQ33375007
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Recombinant human IFN-alpha inhibits cerebral malaria and reduces parasite burden in miceQ45027585
Interferon-alpha receptor-1 (IFNAR1) variants are associated with protection against cerebral malaria in the GambiaQ46314428
A Duffy binding-like domain is involved in the NKp30-mediated recognition of Plasmodium falciparum-parasitized erythrocytes by natural killer cellsQ46607865
Type I interferons contribute to experimental cerebral malaria development in response to sporozoite or blood-stage Plasmodium berghei ANKA.Q47826573
Nonopsonic monocyte/macrophage phagocytosis of Plasmodium falciparum-parasitized erythrocytes: a role for CD36 in malarial clearance.Q47873176
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Dual effect of Plasmodium-infected erythrocytes on dendritic cell maturation.Q33741807
Protein-DNA complex is the exclusive malaria parasite component that activates dendritic cells and triggers innate immune responsesQ33776347
Genome-wide expression profiling in malaria infection reveals transcriptional changes associated with lethal and nonlethal outcomesQ34033935
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Common and divergent immune response signaling pathways discovered in peripheral blood mononuclear cell gene expression patterns in presymptomatic and clinically apparent malaria.Q35073924
Linkage maps from multiple genetic crosses and loci linked to growth-related virulent phenotype in Plasmodium yoeliiQ35149755
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Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.Q35629356
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Manipulation of host innate immune responses by the malaria parasiteQ36805062
Persistent LCMV infection is controlled by blockade of type I interferon signalingQ36808119
Reduced interferon (IFN)-α conditioned by IFNA2 (-173) and IFNA8 (-884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortalityQ36880546
Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function.Q37133197
Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulenceQ37182642
MAPK-activated protein kinase 2 differentially regulates plasmodium falciparum glycosylphosphatidylinositol-induced production of tumor necrosis factor-{alpha} and interleukin-12 in macrophagesQ37257347
Inflammatory pathways in malaria infection: TLRs share the stage with other components of innate immunity.Q37274130
Interferon-γ--central mediator of protective immune responses against the pre-erythrocytic and blood stage of malariaQ37770828
Host resistance to malaria: using mouse models to explore the host responseQ37813458
Innate recognition of malarial parasites by mammalian hostsQ38006306
Caspase-1 activation of interleukin-1β (IL-1β) and IL-18 is dispensable for induction of experimental cerebral malariaQ38284130
Induction of experimental cerebral malaria is independent of TLR2/4/9.Q39171649
Innate immune responses to human malaria: heterogeneous cytokine responses to blood-stage Plasmodium falciparum correlate with parasitological and clinical outcomesQ39571544
Experimental cerebral malaria progresses independently of the Nlrp3 inflammasomeQ39576316
Intercellular adhesion molecule-1 and CD36 synergize to mediate adherence of Plasmodium falciparum-infected erythrocytes to cultured human microvascular endothelial cellsQ39794107
Expression of the cyclin-dependent kinase inhibitor p27 and its deregulation in mouse B cell lymphomasQ40381482
From malaria to chemokine receptor: the emerging physiologic role of the Duffy blood group antigenQ41453601
Blockade of chronic type I interferon signaling to control persistent LCMV infectionQ41807293
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoinQ41912941
Monocyte-derived dendritic cells perform hemophagocytosis to fine-tune excessive immune responsesQ42247803
IFNAR1 controls progression to cerebral malaria in children and CD8+ T cell brain pathology in Plasmodium berghei-infected miceQ44082536
Expression of non-TLR pattern recognition receptors in the spleen of BALB/c mice infected with Plasmodium yoelii and Plasmodium chabaudi chabaudi AS.Q44186148
CD36 mediates the phagocytosis of Plasmodium falciparum-infected erythrocytes by rodent macrophagesQ44727657
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
P304page(s)E511-20
P577publication date2014-01-13
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleStrain-specific innate immune signaling pathways determine malaria parasitemia dynamics and host mortality
P478volume111

Reverse relations

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