Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription

scientific article published on July 1991

Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1991PNAS...88.6229H
P356DOI10.1073/PNAS.88.14.6229
P932PMC publication ID52056
P698PubMed publication ID1712484
P5875ResearchGate publication ID21442266

P2093author name stringS L Schreiber
M W Albers
R J Hohman
T Hultsch
P2860cites workThe immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells.Q45110090
IgE-induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clonesQ52834043
Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycinQ54338613
Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophoresQ59052484
Production of the haemopoietic growth factors GM-CSF and interleukin-3 by mast cells in response to IgE receptor-mediated activationQ59070205
Naming a targeting signalQ68181361
Biochemical characterization of the inhibitory effect of CsA on cytolytic T lymphocyte effector functionsQ69344618
A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomeraseQ24296311
A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilinQ28238996
Cyclosporin A: new insights for cell biologists and biochemistsQ33353959
Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycinQ33911404
FK 506 for liver, kidney, and pancreas transplantationQ34252199
Probing Immunosuppressant Action with a Nonnatural Immunophilin LigandQ34569267
The effect of immunosuppressive agents on the induction of nuclear factors that bind to sites on the interleukin 2 promoterQ36354146
Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokinesQ36356540
Chemistry and Biology of the Immunophilins and Their Immunosuppressive LigandsQ36617985
Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcriptionQ37564002
Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activationQ38342696
Antibody-cell interactions: Fc receptorsQ38630821
Cytoplasmic anchoring proteins and the control of nuclear localizationQ38738339
Membrane phosphoinositide-activated signals in mast cells and basophilsQ39270323
Signal transduction and cellular response in RBL-2H3 mast cellsQ39270360
The receptor with high affinity for immunoglobulin E.Q39501834
Treatment with dexamethasone down-regulates IgE-receptor-mediated signals and up-regulates adenosine-receptor-mediated signals in a rat mast cell (RBL-2H3) line.Q41754205
A comparison of cyclosporine binding by cyclophilin and calmodulin and the identification of a novel 45 KD cyclosporine-binding phosphoprotein in Jurkat cells.Q43523101
Quantitative relationships between aggregation of IgE receptors, generation of intracellular signals, and histamine secretion in rat basophilic leukemia (2H3) cells. Enhanced responses with heavy waterQ43624624
Induction of Interleukin 2 Messenger RNA Inhibited by Cyclosporin AQ43914114
Assessment of IgE-receptor function through measurement of hydrolysis of membrane inositol phospholipids. New insights on the phenomena of biphasic antigen concentration-response curves and desensitizationQ44022608
Suppression of B cell activation by cyclosporin A, FK506 and rapamycinQ44832153
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectexocytosisQ323426
P304page(s)6229-6233
P577publication date1991-07-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleImmunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription
P478volume88

Reverse relations

cites work (P2860)
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Q33598696Airway nerves and protein phosphatases.
Q50685651Calcineurin activation is only one calcium-dependent step in cytotoxic T lymphocyte granule exocytosis.
Q28277749Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
Q70901396Calmodulin is the divalent cation receptor for rapid endocytosis, but not exocytosis, in adrenal chromaffin cells
Q39291738Cathepsin G induces cell aggregation of human breast cancer MCF-7 cells via a 2-step mechanism: catalytic site-independent binding to the cell surface and enzymatic activity-dependent induction of the cell aggregation
Q41614974Comparison of the properties of the CsA analogs monoacetyl CyC (o-acetyl-threonine2 cyclosporin) and methyl-alanyl CsA (N-methyl-L-alanyl6 cyclosporin); monoacetyl cyclosporin is immunosuppressive without binding to cyclophilin
Q29031637Cyclophilin-dependent stimulation of transcription by cyclosporin A
Q46320823Cyclosporine and the renin-angiotensin axis
Q70785785Effect of cyclosporin analogues on histamine release from rat peritoneal mast cells and rat basophilic leukaemia cells
Q71621319Effects of FK506 and cyclosporin A on proliferation, histamine release and phenotype of murine mast cells
Q37199196Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12
Q44491856Effects of immunomodulators on airways hyperresponsiveness to adenosine induced in actively sensitised Brown Norway rats by exposure to allergen
Q41891469Effects of the immunosuppressants cyclosporin A and FK 506 on exocytosis in the rat exocrine pancreas in vitro
Q37892648FK-506-binding proteins from streptomycetes producing immunosuppressive macrolactones of the FK-506 type
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Q47753644Global environmental pollutant substance vanadium activates mast cells and basophils at the late phase in the presence of hydrogen peroxide
Q43228328Hemorphins act as homeostatic agents in response to endotoxin-induced stress
Q48445337High brain densities of the immunophilin FKBP colocalized with calcineurin
Q44280701Human basophil histamine release is differently affected by inhibitors of calmodulin, diacylglycerol kinase and peptidyl prolyl cis‐trans isomerase in a secretagogue specific manner
Q41941546Immunophilin regulation of neurotransmitter release
Q40429841Immunophilins and nervous system
Q41820295Immunosuppressants FK506 and rapamycin have different effects on the biosynthesis of cytoplasmic actin during the early period of T cell activation
Q39473333In Vitro Fusion of Reticulocyte Endocytic Vesicles with Liposomes
Q41837128Inhibition by the immunosuppressive agent FK-506 of antigen-induced airways eosinophilia and bronchial hyperreactivity in mice
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Q36184530Mast cell tumor necrosis factor alpha production is regulated by MEK kinases
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