VKORC1 and CYP2C9 polymorphisms related to adverse events in case-control cohort of anticoagulated patients

scientific article published on December 2016

VKORC1 and CYP2C9 polymorphisms related to adverse events in case-control cohort of anticoagulated patients is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1097/MD.0000000000005451
P932PMC publication ID5207541
P698PubMed publication ID28033245

P2093author name stringStefano Calza
Eleonora Marchina
Luigi Caimi
Alessandra Marengoni
Sophie Testa
Giuliana Martini
Oriana Paoletti
Giovanni Scovoli
Silvia Misasi
P2860cites workUse of Direct Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart LesionsQ26764853
Anticoagulant Treatment of Deep Vein Thrombosis and Pulmonary Embolism: The Present State of the ArtQ26776112
Influence of CYP2C9 and VKORC1 on patient response to warfarin: a systematic review and meta-analysisQ27002899
Crystal structure of human cytochrome P450 2C9 with bound warfarinQ27641685
Structural and functional insights into enzymes of the vitamin K cycleQ28086880
Vitamin K epoxide reductase complex subunit 1 (VKORC1): the key protein of the vitamin K cycleQ28238539
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2Q28242581
Identification of the gene for vitamin K epoxide reductaseQ28242592
Clinical Practice Recommendations on Genetic Testing of CYP2C9 and VKORC1 Variants in Warfarin TherapyQ28265249
Influence of CYP2C9 and VKORC1 genotypes on the risk of hemorrhagic complications in warfarin-treated patients: a systematic review and meta-analysisQ28296211
Estimation of the warfarin dose with clinical and pharmacogenetic dataQ33410725
Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding riskQ33617751
Genetic risk factors for major bleeding in patients treated with warfarin in a community settingQ33792352
Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice GuidelinesQ34252907
A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.Q34418092
Effect of VKORC1 haplotypes on transcriptional regulation and warfarin doseQ34423204
Genotype-guided vs clinical dosing of warfarin and its analogues: meta-analysis of randomized clinical trialsQ34425072
Warfarin pharmacogeneticsQ34785072
Genotype and risk of major bleeding during warfarin treatmentQ35006973
Clinical benefits of pharmacogenetic algorithm-based warfarin dosing: meta-analysis of randomized controlled trialsQ35550476
Concomitant Use of Single Antiplatelet Therapy With Edoxaban or Warfarin in Patients With Atrial Fibrillation: Analysis From the ENGAGE AF-TIMI48 TrialQ36713982
The largest prospective warfarin-treated cohort supports genetic forecastingQ37071087
Influence of CYP2C9 genotype on warfarin dose requirements--a systematic review and meta-analysisQ37334140
A pharmacogenetic versus a clinical algorithm for warfarin dosingQ37616712
Cytochrome P450 2C9-CYP2C9.Q37691210
Epidemiology and characteristics of adverse drug reactions caused by drug-drug interactions.Q37948826
Hospital admissions/visits associated with drug-drug interactions: a systematic review and meta-analysis.Q38194997
Oral anticoagulation: a critique of recent advances and controversiesQ38362468
Genotype-guided dosing of vitamin K antagonistsQ42844131
VKORC1 -1639G>A and CYP2C9*3 are the major genetic predictors of phenprocoumon dose requirementQ43106358
Genetics and the clinical response to warfarin and edoxaban: findings from the randomised, double-blind ENGAGE AF-TIMI 48 trial.Q49142379
The bleeding risk during warfarin therapy is associated with the number of variant alleles of CYP2C9 and VKORC1 genes.Q50901189
Universal versus genotype-guided use of direct oral anticoagulants in atrial fibrillation patients: a decision analysis.Q50950032
A randomized trial of genotype-guided dosing of warfarin.Q51140132
Simultaneous use of amiodarone influences warfarin maintenance dose but is not associated with adverse events.Q53092407
Does Statin Therapy Decrease the Risk for Bleeding in Patients Who Are Receiving Warfarin?Q57491218
The impact of simvastatin on warfarin disposition and dose requirementsQ63241946
VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection)Q82891113
Association between VKORC1 gene polymorphisms and ischemic cerebrovascular disease in Chinese Han populationQ87307841
Outcomes of pharmacogenetics-guided dosing of warfarin: a systematic review and meta-analysisQ87368965
P433issue52
P407language of work or nameEnglishQ1860
P304page(s)e5451
P577publication date2016-12-01
P1433published inMedicineQ15716652
P1476titleVKORC1 and CYP2C9 polymorphisms related to adverse events in case-control cohort of anticoagulated patients
P478volume95

Reverse relations

cites work (P2860)
Q57794673Frequencies of poor metabolizer alleles of 12 pharmacogenomic actionable genes in Punjabi Sikhs of Indian Origin
Q89767315Genome-Wide Association Study of VKORC1 and CYP2C9 on acenocoumarol dose, stroke recurrence and intracranial haemorrhage in Spain
Q48665970The Impact of Gene Polymorphisms on Anticoagulation Control With Warfarin.
Q53823783Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition.

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