The use of carbapenems in the treatment of serious infections

scientific article published on 17 July 2009

The use of carbapenems in the treatment of serious infections is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1177/0885066609335660
P698PubMed publication ID19617229

P2093author name stringRobert P Baughman
P2860cites workGuidelines for the Management of Adults with Hospital-acquired, Ventilator-associated, and Healthcare-associated PneumoniaQ22241905
Comparative stability of carbapenem and penem antibiotics to human recombinant dehydropeptidase-IQ24314556
Plasmid-determined AmpC-type beta-lactamasesQ24535748
Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumoniaQ28286874
Multidrug-resistant Acinetobacter baumanniiQ28306885
Epidemiology of ciprofloxacin resistance and its relationship to extended-spectrum beta-lactamase production in Klebsiella pneumoniae isolates causing bacteremia.Q54058575
Ventilator-associated pneumonia caused by potentially drug-resistant bacteria.Q54146487
Survey of the susceptibility of urinary isolates to antibacterial agents in 2003.Q54490883
Post-antibiotic effect of beta-lactam antibiotics on gram-negative bacteria in relation to morphology, initial killing and MIC.Q54689513
The Value of Routine Microbial Investigation in Ventilator-Associated PneumoniaQ57238120
Absence of convulsive liability of doripenem, a new carbapenem antibiotic, in comparison with beta-lactam antibioticsQ48611808
Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults: a randomized trialQ51643088
Antibiotic resistance in Escherichia coli outpatient urinary isolates: final results from the North American Urinary Tract Infection Collaborative Alliance (NAUTICA).Q51804187
Of Pseudomonas, porins, pumps and carbapenemsQ54018502
Influence of the MexA-MexB-oprM multidrug efflux system on expression of the MexC-MexD-oprJ and MexE-MexF-oprN multidrug efflux systems in Pseudomonas aeruginosaQ54027874
Association of antibiotic utilization measures and control of multiple-drug resistance in Klebsiella pneumoniaeQ54042026
Antimicrobial resistance in Enterobacteriaceae in Brooklyn, NY: epidemiology and relation to antibiotic usage patternsQ54049533
Safety profile of meropenem: a review of nearly 5,000 patients treated with meropenemQ28378163
Emergence of resistance to imipenem in Pseudomonas aeruginosaQ30451746
National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004.Q30977541
Antimicrobial resistance in intensive care unitsQ33673770
In vitro activity of doripenem (S-4661) against multidrug-resistant gram-negative bacilli isolated from patients with cystic fibrosisQ33836698
Short-course empiric antibiotic therapy for patients with pulmonary infiltrates in the intensive care unit. A proposed solution for indiscriminate antibiotic prescriptionQ33912931
Bronchoscopic BAL in the diagnosis of ventilator-associated pneumoniaQ33921191
Use of pharmacokinetic-pharmacodynamic target attainment analyses to support phase 2 and 3 dosing strategies for doripenemQ33935441
Practice guidelines for the management of bacterial meningitisQ33982444
Risk factors for emergence of resistance to broad-spectrum cephalosporins among Enterobacter spp.Q33982975
Cefepime, Piperacillin-Tazobactam, and the Inoculum Effect in Tests with Extended-Spectrum β-Lactamase-Producing EnterobacteriaceaeQ33983667
Inadequate antimicrobial treatment: an important determinant of outcome for hospitalized patientsQ34052619
SHV-type extended-spectrum beta-lactamase production is associated with Reduced cefepime susceptibility in Enterobacter cloacaeQ34073514
Comparative stability studies of antipseudomonal beta-lactams for potential administration through portable elastomeric pumps (home therapy for cystic fibrosis patients) and motor-operated syringes (intensive care units)Q34111057
2002 guidelines for the use of antimicrobial agents in neutropenic patients with cancerQ34114674
Controversies about extended-spectrum and AmpC beta-lactamasesQ34213755
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shockQ34314380
Overview of nosocomial infections caused by gram-negative bacilliQ34444001
Practice guidelines for the diagnosis and management of skin and soft-tissue infectionsQ34460523
Empirical antibiotic monotherapy for febrile neutropenia: systematic review and meta-analysis of randomized controlled trialsQ34475273
The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU settingQ34509624
Clinical and economic impact of bacteremia with extended- spectrum-beta-lactamase-producing Enterobacteriaceae.Q34510547
Antimicrobial susceptibility among pathogens collected from hospitalized patients in the United States and in vitro activity of tigecycline, a new glycylcycline antimicrobialQ34569412
Occurrence of carbapenem-resistant Acinetobacter baumannii clones at multiple hospitals in London and Southeast EnglandQ34571574
Treatment with a broad-spectrum cephalosporin versus piperacillin-tazobactam and the risk for isolation of broad-spectrum cephalosporin-resistant Enterobacter speciesQ35014507
AmpC beta-lactamases: what do we need to know for the future?Q35140531
Nosocomial infections adversely affect the outcomes of patients with serious intraabdominal infectionsQ35772778
Is it safe to use carbapenems in patients with a history of allergy to penicillin?Q35919005
Clinical outcome of bacteremic spontaneous bacterial peritonitis due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae.Q35936876
Appropriate and timely empirical antimicrobial treatment of icu infections--a role for carbapenemsQ36219506
Nosocomial infections due to multidrug-resistant Pseudomonas aeruginosa: epidemiology and treatment optionsQ36268383
Empiric treatment of nosocomial intra-abdominal infections: a focus on the carbapenemsQ36275481
Clinical and economic consequences of ventilator-associated pneumonia: a systematic review.Q36282000
An overview of the Meropenem Yearly Susceptibility Test Information Collection (MYSTIC) Program: 1997-2004.Q36344982
DoripenemQ36538130
Doripenem versus Pseudomonas aeruginosa in vitro: activity against characterized isolates, mutants, and transconjugants and resistance selection potentialQ36670323
Impact of BAL data on the therapy and outcome of ventilator-associated pneumoniaQ36856249
Comparative activities of doripenem versus isolates, mutants, and transconjugants of Enterobacteriaceae and Acinetobacter spp. with characterized beta-lactamasesQ37120635
Bloodstream infections due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae: risk factors for mortality and treatment outcome, with special emphasis on antimicrobial therapyQ37624439
Class restriction of cephalosporin use to control total cephalosporin resistance in nosocomial KlebsiellaQ39477943
Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patientsQ39487652
Experience with a clinical guideline for the treatment of ventilator-associated pneumoniaQ39570112
Postantibiotic effect of imipenem on Pseudomonas aeruginosaQ39849241
Evolution of fluoroquinolone resistance among Escherichia coli urinary tract isolates from a French university hospital: application of the dynamic regression model.Q40438901
Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections.Q40558538
Meropenem versus ceftazidime in the treatment of cancer patients with febrile neutropenia: a randomized, double-blind trialQ40612851
Validation of different techniques for the diagnosis of ventilator-associated pneumonia. Comparison with immediate postmortem pulmonary biopsyQ40704822
Beta-lactam regimens for the febrile neutropenic patientQ40765968
Randomized trial of beta-lactam regimens in febrile neutropenic cancer patientsQ40788084
Determinants of the activity of beta-lactamase inhibitor combinationsQ40884640
Acquired carbapenemasesQ41530522
High levels of antimicrobial coresistance among extended-spectrum-beta-lactamase-producing Enterobacteriaceae.Q42054872
Risk factors for and clinical outcomes of bloodstream infections caused by extended-spectrum beta-lactamase-producing Klebsiella pneumoniaeQ42167308
Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremiaQ42537148
In vitro activity of doripenem against Pseudomonas aeruginosa and Burkholderia cepacia isolates from both cystic fibrosis and non-cystic fibrosis patientsQ43203176
Variations in the prevalence of strains expressing an extended-spectrum beta-lactamase phenotype and characterization of isolates from Europe, the Americas, and the Western Pacific regionQ43587147
Characterization of Pseudomonas aeruginosa isolates: occurrence rates, antimicrobial susceptibility patterns, and molecular typing in the global SENTRY Antimicrobial Surveillance Program, 1997-1999.Q43587157
In vitro evaluation of ertapenem (MK-0826), a long-acting carbapenem, tested against selected resistant strainsQ43758464
Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare?Q43874264
Risk factors for infection by Pseudomonas aeruginosa in patients with ventilator-associated pneumoniaQ44088492
Sustained activity and spectrum of selected extended-spectrum beta-lactams (carbapenems and cefepime) against Enterobacter spp. and ESBL-producing Klebsiella spp.: report from the SENTRY antimicrobial surveillance program (USA, 1997-2000).Q44266804
Ceftazidime-resistant Klebsiella pneumoniae isolates recovered at the Cleveland Department of Veterans Affairs Medical CenterQ44685672
Antimicrobial usage and resistance trend relationships from the MYSTIC Programme in North America (1999-2001).Q44719256
Ventilator-associated pneumonia patients who do not reduce bacteria from the lungs have a worse prognosisQ44808648
Incidence of carbapenem-associated allergic-type reactions among patients with versus patients without a reported penicillin allergyQ44850126
Pharmacokinetic properties and stability of continuous-infusion meropenem in adults with cystic fibrosisQ44930989
Bloodstream infections caused by Enterobacter species: predictors of 30-day mortality rate and impact of broad-spectrum cephalosporin resistance on outcomeQ45097000
The OPTAMA programme: utilizing MYSTIC (2002) to predict critical pharmacodynamic target attainment against nosocomial pathogens in EuropeQ45170003
Pharmacodynamic modeling of carbapenems and fluoroquinolones against bacteria that produce extended-spectrum beta-lactamases.Q45216688
Ertapenem-associated seizures in a peritoneal dialysis patientQ45219997
Acute seizures due to a probable interaction between valproic acid and meropenem.Q45258188
In vivo development of ertapenem resistance in a patient with pneumonia caused by Klebsiella pneumoniae with an extended-spectrum beta-lactamaseQ46435439
Comparative activity of doripenem and three other carbapenems tested against Gram-negative bacilli with various beta-lactamase resistance mechanismsQ46476490
Seizure worsening caused by decreased serum valproate during meropenem therapyQ46558607
Epidemiology and microbiology of hospital-acquired pneumoniaQ46641627
Pharmacodynamic modeling of beta-lactam antibiotics for the empiric treatment of secondary peritonitis: a report from the OPTAMA programQ46733453
Pharmacodynamics of antimicrobials for the empirical treatment of nosocomial pneumonia: a report from the OPTAMA ProgramQ46744338
Study of the synergism between carbapenems and vancomycin or teicoplanin against MRSA, focusing on S-4661, a carbapenem newly developed in JapanQ46782435
Antimicrobial activity of doripenem (S-4661): a global surveillance report (2003).Q46819792
Activity of meropenem and comparators against Pseudomonas aeruginosa and Acinetobacter spp. isolated in the MYSTIC Program, 2002-2004.Q46855855
Pharmacodynamic modeling of imipenem-cilastatin, meropenem, and piperacillin-tazobactam for empiric therapy of skin and soft tissue infections: a report from the OPTAMA ProgramQ46909106
Respiratory nosocomial infections in the medical intensive care unitQ47843096
Important and Emerging β-Lactamase-mediated Resistances in Hospital-based Pathogens: The Amp C EnzymesQ47946026
Aminoglycosides for intra-abdominal infection: equal to the challenge?Q47972158
P433issue4
P921main subjectcarbapenem antibioticQ410897
P304page(s)230-241
P577publication date2009-07-17
P13046publication type of scholarly workreview articleQ7318358
P1433published inJournal of Intensive Care MedicineQ6295377
P1476titleThe use of carbapenems in the treatment of serious infections
P478volume24

Reverse relations

cites work (P2860)
Q40158594A permission system for carbapenem use reduced incidence of drug-resistant bacteria and cost of antimicrobials at a general hospital in Japan
Q36417501Acinetobacter baumanniiSepticemia in a Recipient of an Allogeneic Hematopoietic Stem Cell Transplantation
Q27660367Biochemical and Structural Characterization of Mycobacterium tuberculosis β-Lactamase with the Carbapenems Ertapenem and Doripenem
Q53714289Carbapenem Resistance: A Review
Q38052888Clinical Outcomes With Extended or Continuous Versus Short-term Intravenous Infusion of Carbapenems and Piperacillin/Tazobactam: A Systematic Review and Meta-analysis
Q92327785Comparison of Four Commercial Screening Assays for the Detection of blaKPC, blaNDM, blaIMP, blaVIM, and blaOXA48 in Rectal Secretion Collected by Swabs
Q38865064Comparison of in vitro activities of meropenem productions on Klebsiella pneumoniae isolated from hospitalized patients
Q37825731Current challenges in the management of the infected patient
Q92289384Detection of Enterobacterales resistant to polymyxins using Rapid Polymyxins NP test
Q36396195Dosing nomograms for attaining optimum concentrations of meropenem by continuous infusion in critically ill patients with severe gram-negative infections: a pharmacokinetics/pharmacodynamics-based approach
Q50876503Epidemiology and antimicrobial resistance among commonly encountered bacteria associated with infections and colonization in intensive care units in a university-affiliated hospital in Shanghai
Q38016195Extended spectrum β-lactamases, carbapenemases and mobile genetic elements responsible for antibiotics resistance in Gram-negative bacteria.
Q34800304Identification of Products of Inhibition of GES-2 β-Lactamase by Tazobactam by X-ray Crystallography and Spectrometry
Q92353271In vitro activities of colistin, imipenem and ceftazidime against drug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii isolates in the south of Iran
Q37810405Management of Complicated Urinary Tract Infections in the Era of Antimicrobial Resistance
Q59101206Mutant prevention concentrations of imipenem and meropenem against Pseudomonas aeruginosa and Acinetobacter baumannii
Q88801950Pharmacokinetics of imipenem in plasma and cerebrospinal fluid in patients with intracerebral hemorrhage
Q36029984Prevalence and Fate of Carbapenemase Genes in a Wastewater Treatment Plant in Northern China.
Q27670446Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712
Q33992526Urinary Tract Infections in the Elderly Population
Q38872374β-Lactams and β-Lactamase Inhibitors: An Overview

Search more.