Functions of microRNAs in cardiovascular biology and disease

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Functions of microRNAs in cardiovascular biology and disease is …
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scholarly articleQ13442814

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P356DOI10.1146/ANNUREV-PHYSIOL-030212-183737
P932PMC publication ID5215839
P698PubMed publication ID23157557

P2093author name stringAkiko Hata
P2860cites workThe Long Non-Coding RNAs: A New (P)layer in the "Dark Matter"Q21131257
MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansionQ24305799
TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylationQ24308810
Lin28 mediates the terminal uridylation of let-7 precursor MicroRNAQ24308839
miR-145 and miR-143 regulate smooth muscle cell fate and plasticityQ24311186
miR-126 regulates angiogenic signaling and vascular integrityQ24569770
Characterization of extracellular circulating microRNAQ24603537
MiR-15 family regulates postnatal mitotic arrest of cardiomyocytesQ24604386
The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human diseaseQ24606673
Circulating microRNAs are new and sensitive biomarkers of myocardial infarctionQ24606701
MicroRNAs: target recognition and regulatory functionsQ24609584
Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in miceQ24623247
MiR-33 contributes to the regulation of cholesterol homeostasis.Q39704194
Maturation of microRNA is hormonally regulated by a nuclear receptorQ39783905
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heartQ40036277
MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formationQ41166615
Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humansQ41412919
Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytesQ42535729
Zebrafish microRNA-126 determines hematopoietic cell fate through c-MybQ42674086
Expression of miR-146a/b is associated with the Toll-like receptor 4 signal in coronary artery disease: effect of renin-angiotensin system blockade and statins on miRNA-146a/b and Toll-like receptor 4 levelsQ43044147
Conditional dicer gene deletion in the postnatal myocardium provokes spontaneous cardiac remodelingQ43557501
Dysregulation of angiogenesis-related microRNAs in endothelial progenitor cells from patients with coronary artery diseaseQ44634303
MicroRNA profiling during mouse ventricular maturation: a role for miR-27 modulating Mef2c expression.Q51901308
Circulating microRNAs in patients with coronary artery disease.Q54421687
MiR423-5p as a circulating biomarker for heart failure.Q54439825
MicroRNA-29 in Aortic Dilation: Implications for Aneurysm FormationQ58816127
A Role for miR-145 in Pulmonary Arterial HypertensionQ63916426
MicroRNA-26a is a novel regulator of vascular smooth muscle cell functionQ24624403
miR-122 continues to blaze the trail for microRNA therapeuticsQ24628313
MicroRNA-218 Regulates Vascular Patterning by Modulation of Slit-Robo SignalingQ24630924
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clustersQ24645192
MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injuryQ24647407
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failureQ24648103
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiationQ24650204
A necessary role of miR-221 and miR-222 in vascular smooth muscle cell proliferation and neointimal hyperplasiaQ24650572
MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heat-shock protein 20Q24651483
A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequenceQ24652491
miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elementsQ24656666
The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesisQ24656947
Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotypeQ24658407
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failureQ24673535
Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypesQ24678210
Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferationQ24679746
Micromanaging vascular smooth muscle cell differentiation and phenotypic modulationQ27026074
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegansQ27860584
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14Q27860849
Widespread changes in protein synthesis induced by microRNAsQ27860886
Identification of novel genes coding for small expressed RNAsQ27860917
Biogenesis of small RNAs in animalsQ27861013
MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in miceQ28115423
Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cellsQ28115799
MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4Q28251320
Posttranscriptional regulation of microRNA biogenesis in animalsQ28282519
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2Q28295844
A cardiac microRNA governs systemic energy homeostasis by regulation of MED13Q28505950
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblastsQ28511032
An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133Q28513095
Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanismQ28586556
The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradientQ28587676
Control of stress-dependent cardiac growth and gene expression by a microRNAQ28587851
Regulation of zebrafish heart regeneration by miR-133Q35928374
Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failureQ35964249
Inhibition of miR-15 protects against cardiac ischemic injuryQ35967093
Emerging functional and mechanistic paradigms of mammalian long non-coding RNAsQ36144721
MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling.Q36475841
The developmental genetics of congenital heart disease.Q37089736
MicroRNA regulation of cardiovascular developmentQ37148254
miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophyQ37274522
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice.Q37328435
Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene clusterQ37328540
MicroRNAs and cardiac pathologyQ37478072
MicroRNA regulation of smooth muscle gene expression and phenotypeQ37580458
Analysis of microRNA knockouts in miceQ37784095
Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease?Q37981140
Primitive erythropoiesis is regulated by miR-126 via nonhematopoietic Vcam-1+ cellsQ39322319
DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAsQ28589022
Dicer is required for embryonic angiogenesis during mouse developmentQ28591059
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAsQ28941769
SMAD proteins control DROSHA-mediated microRNA maturationQ28941771
Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanismQ28941773
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesisQ29547607
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteinsQ29615034
Molecular regulation of vascular smooth muscle cell differentiation in development and diseaseQ29615194
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infectionQ29615959
LNA-mediated microRNA silencing in non-human primatesQ29615962
A family of microRNAs encoded by myosin genes governs myosin expression and muscle performanceQ29619547
Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTRQ29619777
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosisQ29619873
Modulation of microRNA processing by p53Q29620776
microRNA-138 modulates cardiac patterning during embryonic development.Q30484543
MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesisQ30495845
miRNA-processing enzyme Dicer is necessary for cardiac outflow tract alignment and chamber septationQ33591513
Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failureQ33689545
MicroRNA-15b modulates cellular ATP levels and degenerates mitochondria via Arl2 in neonatal rat cardiac myocytesQ33717662
MicroRNAs add a new dimension to cardiovascular diseaseQ33761132
MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and functionQ33893114
miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosisQ34044475
Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotalineQ34095444
The miR-143-adducin3 pathway is essential for cardiac chamber morphogenesisQ34114731
Mechanisms of control of microRNA biogenesis.Q34310633
Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defectsQ34332491
miR‐146a and Krüppel‐like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferationQ34506077
EGFL7 regulates the collective migration of endothelial cells by restricting their spatial distributionQ34649430
miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytesQ34681377
Cardiac plasticityQ34764732
Pervasive roles of microRNAs in cardiovascular biologyQ34775686
Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126.Q34873390
Cell-cell contact globally activates microRNA biogenesis.Q34975000
The role of microRNAs in normal and malignant hematopoiesisQ35002076
down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4Q35150101
Transforming growth factor-beta1 (TGF-beta1) utilizes distinct pathways for the transcriptional activation of microRNA 143/145 in human coronary artery smooth muscle cellsQ35314346
MicroRNA destabilization enables dynamic regulation of the miR-16 family in response to cell-cycle changesQ35456159
P921main subjectmicroRNAQ310899
circulatory systemQ11068
P304page(s)69-93
P577publication date2012-11-13
P1433published inAnnual Review of PhysiologyQ567364
P1476titleFunctions of microRNAs in cardiovascular biology and disease
P478volume75