Tumor necrosis factor alpha induction of NF-kappaB requires the novel coactivator SIMPL.

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Tumor necrosis factor alpha induction of NF-kappaB requires the novel coactivator SIMPL. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.24.21.9317-9326.2004
P932PMC publication ID522234
P698PubMed publication ID15485901
P5875ResearchGate publication ID8230619

P50authorMaureen A. HarringtonQ93818665
P2093author name stringYong Luo
Mark G Goebl
Younghee Lee
Hyung-Joo Kwon
Erin Haag Breese
Eva Vig-Varga
P2860cites workIKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activationQ24321727
A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaBQ24321775
IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIKQ24321797
Delta-opioid receptors expressed by Jurkat T cells enhance IL-2 secretion by increasing AP-1 complexes and activity of the NF-AT/AP-1-binding promoter elementQ24336669
IKK1-deficient mice exhibit abnormal development of skin and skeletonQ24604269
Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alphaQ27622214
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activityQ27860643
SIMPL is a tumor necrosis factor-specific regulator of nuclear factor-kappaB activityQ28138811
NF-kappaB regulation in the immune systemQ28205043
Identification and characterization of an IkappaB kinaseQ28245341
The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activationQ28252726
Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activityQ28276063
Innate immunityQ29618949
Nuclear transport and transcriptional regulationQ33665634
Nuclear targeting signal recognition: a key control point in nuclear transport?Q33936678
Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.Q34061286
Series introduction: the transcription factor NF-kappaB and human diseaseQ34116362
Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interactionQ36689762
Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B familyQ38313406
Genetic analysis of NF- B/Rel transcription factors defines functional specificitiesQ39962410
Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alphaQ40401245
Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulationQ40444107
Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient miceQ40956523
Modulation of tumor necrosis factor and interleukin-1-dependent NF-kappaB activity by mPLK/IRAK.Q40957476
Severe liver degeneration in mice lacking the IkappaB kinase 2 geneQ40962152
Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinaseQ41644582
Limb and skin abnormalities in mice lacking IKKalphaQ42470314
Tumor necrosis factor receptors (Tnfr) in mouse fibroblasts deficient in Tnfr1 or Tnfr2 are signaling competent and activate the mitogen-activated protein kinase pathway with differential kineticsQ71763127
Kinetic characterization of the human retinoblastoma protein bipartite nuclear localization sequence (NLS) in vivo and in vitro. A comparison with the SV40 large T-antigen NLSQ73617977
Toll-like receptors control activation of adaptive immune responsesQ74486847
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
P1104number of pages10
P304page(s)9317-9326
P577publication date2004-11-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleTumor necrosis factor alpha induction of NF-kappaB requires the novel coactivator SIMPL.
P478volume24

Reverse relations

cites work (P2860)
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Q34419611Regulating inducible transcription through controlled localization
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