Regulatory role of TRIM21 in the type-I interferon pathway in Japanese encephalitis virus-infected human microglial cells.

scientific article published on February 2014

Regulatory role of TRIM21 in the type-I interferon pathway in Japanese encephalitis virus-infected human microglial cells. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1047889723
P356DOI10.1186/1742-2094-11-24
P932PMC publication ID3922089
P698PubMed publication ID24485101
P5875ResearchGate publication ID260022206

P50authorAnirban BasuQ30505551
Ritu MishraQ57428648
Gunjan D ManochaQ86018608
P2093author name stringNikhil Sharma
Kanhaiya Lal Kumawat
Sunit K Singh
P2860cites workTRIM5 is an innate immune sensor for the retrovirus capsid latticeQ24300173
TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activityQ24301176
Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.Q24533140
Trim5alpha protein restricts both HIV-1 and murine leukemia virusQ24561922
The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitorsQ24569665
TRIM family proteins and their emerging roles in innate immunityQ24607229
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA virusesQ27860455
Pathogen recognition and innate immunityQ27861084
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6Q28115232
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathwayQ28190704
Triggering the interferon antiviral response through an IKK-related pathwayQ28191761
The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNAQ28507251
TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradationQ28593493
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeysQ29547689
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirusQ29615029
Human TRIM gene expression in response to interferonsQ33418607
Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptorsQ33644464
The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3Q33670447
RIG-I mediates innate immune response in mouse neurons following Japanese encephalitis virus infectionQ33955366
STING mediates neuronal innate immune response following Japanese encephalitis virus infectionQ34265452
Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule bindingQ34487703
Pattern-recognition receptor signaling initiated from extracellular, membrane, and cytoplasmic space.Q34623488
Fas-associated death domain (FADD) and the E3 ubiquitin-protein ligase TRIM21 interact to negatively regulate virus-induced interferon productionQ34675854
Structural mechanism of RNA recognition by the RIG-I-like receptorsQ34808213
TRIM56 is a virus- and interferon-inducible E3 ubiquitin ligase that restricts pestivirus infectionQ35076566
IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblastsQ35122228
TRIM79α, an interferon-stimulated gene product, restricts tick-borne encephalitis virus replication by degrading the viral RNA polymeraseQ35240160
Tripartite motif 8 (TRIM8) modulates TNFα- and IL-1β-triggered NF-κB activation by targeting TAK1 for K63-linked polyubiquitinationQ35585775
Identification of a genomic reservoir for new TRIM genes in primate genomesQ35586967
TRIM22: A Diverse and Dynamic Antiviral ProteinQ35975047
Innate immunity in the pathogenesis of polytropic retrovirus infection in the central nervous systemQ36664660
Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21.Q36903830
Intracellular antibody receptor TRIM21 prevents fatal viral infectionQ37049349
Identification of TRIM23 as a cofactor involved in the regulation of NF-kappaB by human cytomegalovirusQ37145244
Ecology and geographical expansion of Japanese encephalitis virusQ37344877
Tripartite-motif proteins and innate immune regulationQ37815984
Role of promyelocytic leukemia protein in host antiviral defenseQ37825489
Japanese encephalitis virus: from genome to infectome.Q37828968
Expression of the immune regulator tripartite-motif 21 is controlled by IFN regulatory factorsQ39105144
The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptorsQ39188991
Human Trim5α has additional activities that are uncoupled from retroviral capsid recognitionQ39638271
TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral responseQ39876432
Interferon-alpha induces up-regulation and nuclear translocation of the Ro52 autoantigen as detected by a panel of novel Ro52-specific monoclonal antibodiesQ40036932
Cutting edge: autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophagesQ40117899
A retrovirus restriction factor TRIM5alpha is transcriptionally regulated by interferonsQ40351057
Antiviral TRIMs: friend or foe in autoimmune and autoinflammatory disease?Q50513813
TRIM32 promotes neural differentiation through retinoic acid receptor-mediated transcription.Q51851335
Induction of the PML protein by interferons in normal and APL cells.Q52519199
Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells.Q53497217
The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IkappaB kinase family membersQ82176420
E3 ubiquitin ligase tripartite motif 38 negatively regulates TLR-mediated immune responses by proteasomal degradation of TNF receptor-associated factor 6 in macrophagesQ83419945
P921main subjectJapanese encephalitis virusQ19838331
encephalitisQ199615
Japanese encephalitisQ738292
microgliaQ1622829
P304page(s)24
P577publication date2014-02-01
P1433published inJournal of NeuroinflammationQ15716679
P1476titleRegulatory role of TRIM21 in the type-I interferon pathway in Japanese encephalitis virus-infected human microglial cells
P478volume11