Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity

scientific article published on 18 October 2016

Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3892/OL.2016.5286
P932PMC publication ID5228369
P698PubMed publication ID28105192

P2093author name stringHirokazu Inoue
Yukihiro Tambe
Hiroyuki Sugihara
Ken-Ichi Mukaisho
Akihiro Kawauchi
Chul Jang Kim
P2860cites workSerrated lesions of the colorectum: review and recommendations from an expert panelQ26827208
Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformationQ28140810
Targeting RAS signalling pathways in cancer therapyQ28201363
Cyclin D as a therapeutic target in cancerQ28242623
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localizationQ28290083
Cyclin D1: polymorphism, aberrant splicing and cancer riskQ28303053
The phosphatidylinositol 3-Kinase AKT pathway in human cancerQ29547860
Targeting PI3K signalling in cancer: opportunities, challenges and limitationsQ29617685
PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cellsQ33945648
Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulationQ34478869
PKB binding proteins. Getting in on the Akt.Q34990565
Cyclin D1 polymorphism and expression in patients with squamous cell carcinoma of the head and neckQ35788347
Serrated polyps of the large intestine: a morphologic and molecular review of an evolving conceptQ36271250
Sporadic and syndromic hyperplastic polyps and serrated adenomas of the colon: classification, molecular genetics, natural history, and clinical managementQ37099611
Role of the serrated pathway in colorectal cancer pathogenesisQ37737403
Update on the serrated pathway to colorectal carcinomaQ37792441
The drs tumor suppressor regulates glucose metabolism via lactate dehydrogenase-B.Q38916543
Female-specific rectal carcinogenesis in cyclin D1b transgenic miceQ39105154
Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68Q39760025
Cyclin D1b variant promotes cell invasiveness independent of binding to CDK4 in human bladder cancer cellsQ39856793
D-type cyclinsQ40443885
An alternatively spliced cyclin D1 isoform, cyclin D1b, is a nuclear oncogeneQ40617469
Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformationQ42801826
Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16Q59082348
Cyclin D1 (PRAD1) alternative transcript b: full-length cDNA cloning and expression in breast cancersQ73145251
The cyclin D1 alternative transcripts [a] and [b] are expressed in normal and malignant lymphocytes and their relative levels are influenced by the polymorphism at codon 241Q74063854
CYCLIN D1 as a genetic modifier in hereditary nonpolyposis colorectal cancerQ74379510
P433issue6
P921main subjectneoplastic invasivenessQ112498967
P304page(s)4850-4856
P577publication date2016-10-18
P1433published inOncology LettersQ20640514
P1476titleAkt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity
P478volume12

Reverse relations

Q52564290Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics.cites workP2860