MitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress.

scientific article published on 02 January 2017

MitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress. is …
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scholarly articleQ13442814

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P356DOI10.1155/2017/7528090
P932PMC publication ID5237742
P698PubMed publication ID28116040

P50authorShaogang WangQ87737681
Jiaqiao ZhangQ89949070
Qing WangQ89949075
Chuou XuQ89949077
Yuchao LuQ89949080
Henglong HuQ89949082
Baolong QinQ89949086
Yufeng WangQ89949087
Deng HeQ89949090
Cong LiQ89949093
P2093author name stringXiao Yu
Jihong Liu
P2860cites workTargeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancersQ21198861
NADPH oxidase as a therapeutic target for oxalate induced injury in kidneysQ27014373
Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical IndicationsQ27024762
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Cross talk between mitochondria and NADPH oxidasesQ28391403
Vitamin E attenuates crystal formation in rat kidneys: roles of renal tubular cell death and crystallization inhibitorsQ28564916
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasomeQ29547419
Superoxide from NADPH oxidase as second messenger for the expression of osteopontin and monocyte chemoattractant protein-1 in renal epithelial cells exposed to calcium oxalate crystalsQ33409620
Regulation of macromolecular modulators of urinary stone formation by reactive oxygen species: transcriptional study in an animal model of hyperoxaluriaQ33701562
Astaxanthin modulates osteopontin and transforming growth factor β1 expression levels in a rat model of nephrolithiasis: a comparison with citrate administration.Q51743065
Hydrogen peroxide enhances osteopontin expression and matrix metalloproteinase activity in aortic vascular smooth muscle cells.Q54503417
Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS releaseQ33913079
Apocynin-treatment reverses hyperoxaluria induced changes in NADPH oxidase system expression in rat kidneys: a transcriptional studyQ34455371
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)Q34681297
The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4Q34787163
C-phycocyanin confers protection against oxalate-mediated oxidative stress and mitochondrial dysfunctions in MDCK cellsQ35137549
Oxalobacter formigenes may reduce the risk of calcium oxalate kidney stones.Q36677659
NADPH oxidases, reactive oxygen species, and the kidney: friend and foe.Q37202752
Exposure of Madin-Darby canine kidney (MDCK) cells to oxalate and calcium oxalate crystals activates nicotinamide adenine dinucleotide phosphate (NADPH)-oxidaseQ37531517
Mitochondrial reactive oxygen species drive proinflammatory cytokine productionQ37847792
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Involvement of renin-angiotensin-aldosterone system in calcium oxalate crystal induced activation of NADPH oxidase and renal cell injuryQ38874052
The selective NADPH oxidase inhibitor apocynin has potential prophylactic effects on melamine-related nephrolithiasis in vitro and in vivoQ38947632
Temporal changes in the expression of mRNA of NADPH oxidase subunits in renal epithelial cells exposed to oxalate or calcium oxalate crystalsQ39631531
NF-kappaB activation in renal tubular epithelial cells by oxalate stimulation.Q39948151
Oxalate stimulates IL-6 production in HK-2 cells, a line of human renal proximal tubular epithelial cellsQ40398277
Mitochondrial dysfunction is a primary event in renal cell oxalate toxicityQ40501754
Effect of NADPH oxidase inhibition on the expression of kidney injury molecule and calcium oxalate crystal deposition in hydroxy-L-proline-induced hyperoxaluria in the male Sprague-Dawley ratsQ41919477
Does crystal deposition in genetic hypercalciuric rat kidney tissue share similarities with bone formation?Q42453166
Mitochondrial superoxide production during oxalate-mediated oxidative stress in renal epithelial cellsQ44022921
Urinary IL-6 is elevated in patients with urolithiasisQ46103663
Vitamin E therapy prevents hyperoxaluria-induced calcium oxalate crystal deposition in the kidney by improving renal tissue antioxidant statusQ46552906
High Concentration of Calcium Stimulates Calcium Oxalate Crystal Attachment to Rat Tubular Epithelial NRK Cells Through OsteopontinQ46694235
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectmitochondrionQ39572
P304page(s)7528090
P577publication date2017-01-02
P1433published inOxidative medicine and cellular longevityQ26840015
P1476titleMitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress
P478volume2017