Effect of pharmaceutical interventions targeting thromboxane receptors and thromboxane synthase in cardiovascular and renal diseases

scientific article published on September 2009

Effect of pharmaceutical interventions targeting thromboxane receptors and thromboxane synthase in cardiovascular and renal diseases is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.2217/FCA.09.33
P698PubMed publication ID19715412

P2093author name stringPierre Fontana
Henri Bounameaux
Alexandra Santana Sorensen
Jessica Mann
Kjell S Sakariassen
Peteris Alberts
P2860cites workAspirin for the Primary Prevention of Cardiovascular Events: An Update of the Evidence for the U.S. Preventive Services Task ForceQ22305330
Testosterone Increases Human Platelet Thromboxane A2 Receptor Density and Aggregation ResponsesQ22306390
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Picotamide, a combined inhibitor of thromboxane A2 synthase and receptor, reduces 2-year mortality in diabetics with peripheral arterial disease: the DAVID studyQ28171078
Effect of aspirin on prostanoids and nitric oxide production in streptozotocin-diabetic rats with ischemic retinopathyQ28192250
Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non-platelet-mediated effectsQ28193542
Aspirin protects endothelial cells from oxidant damage via the nitric oxide-cGMP pathwayQ28196567
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Prevalence of persistent platelet reactivity despite use of aspirin: a systematic reviewQ28217967
Resistance to antiplatelet drugs: molecular mechanisms and laboratory detectionQ28218540
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Vascular endothelial cells synthesize nitric oxide from L-arginineQ28291036
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Binding characteristics of the new thromboxane A2/prostaglandin H2 receptor antagonist [3H]BAY U 3405 to washed human platelets and platelet membranesQ28316520
Increased glomerular thromboxane synthesis as a possible cause of proteinuria in experimental nephrosisQ28362606
Additions and Corrections to Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A(2) receptorQ30051401
Oxidative stress and cardiovascular complications in diabetes: isoprostanes as new markers on an old paradigm.Q34017497
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Isoprostanes and the kidneyQ36009409
Thromboembolic complications in the nephrotic syndrome: pathophysiology and clinical managementQ36180173
From the design to the clinical application of thromboxane modulatorsQ36419627
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Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: a systematic review and meta-analysis.Q36887785
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A role for the thromboxane receptor in L-NAME hypertensionQ36956758
Defining the role of platelet glycoprotein receptor inhibitors in STEMI: focus on tirofiban.Q37385355
Antithrombotic agents in the prevention of ischemic strokeQ37480441
Rationale and design of the Prevention of Cerebrovascular and Cardiovascular Events of Ischemic Origin with Terutroban in Patients with a History of Ischemic Stroke or Transient Ischemic Attack (PERFORM) StudyQ37480454
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Phosphorylation of the thromboxane receptor alpha, the predominant isoform expressed in human platelets.Q40978901
Serum albumin enhances the impairment of platelet aggregation with thromboxane synthase inhibition by increasing the formation of prostaglandin D2.Q42249127
Antiproteinuric effect of a thromboxane receptor antagonist, S-1452, on rat diabetic nephropathy and murine lupus nephritisQ42281442
Influence of albuminuria on cardiovascular risk in patients with stable coronary artery diseaseQ43841703
Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats.Q44321794
The Thromboxane Receptor Antagonist PBT-3, a Hepoxilin Stable Analog, Selectively Antagonizes the TPα Isoform in Transfected COS-7 CellsQ44618366
Role for thromboxane receptors in angiotensin-II-induced hypertension.Q44725166
Thromboxane blockade reduces blood pressure and progression of renal failure independent of endothelin-1 in uremic ratsQ44944758
Thromboxane A2 receptor signaling inhibits vascular endothelial growth factor-induced endothelial cell differentiation and migrationQ44970389
Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathyQ45012594
Thromboxane receptor blockade reduces renal injury in murine lupus nephritisQ45055157
Thromboxane biosynthesis and platelet function in type II diabetes mellitusQ45056796
Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart StudyQ45181167
Atherosclerosis regression and TP receptor inhibition: effect of S18886 on plaque size and composition--a magnetic resonance imaging studyQ45285281
Increased platelet thromboxane synthesis in renal glomerular diseasesQ45791338
The relationship between magnitude of proteinuria reduction and risk of end-stage renal disease: results of the African American study of kidney disease and hypertensionQ46169157
Aspirin 'resistance': role of pre-existent platelet reactivity and correlation between testsQ46265322
Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents.Q46418076
The novel phosphodiesterase inhibitor NM-702 improves claudication-limited exercise performance in patients with peripheral arterial diseaseQ46505199
The specific thromboxane receptor antagonist S18886: pharmacokinetic and pharmacodynamic studies.Q46566202
The selective TP receptor antagonist, S18886 (terutroban), attenuates renal damage in the double transgenic rat model of hypertensionQ46985304
Shear-induced platelet adhesion and aggregation on subendothelium are increased in diabetic patientsQ47734969
Role of ADP and thromboxanes in human thrombus formation in ex vivo models.Q51174787
Carotid artery disease in NIDDM diabetes.Q51645371
The continuous administration of aspirin attenuates atherosclerosis in apolipoprotein E-deficient mice.Q54019410
Long-term treatment with the dual antithromboxane agent picotamide decreases microalbuminuria in normotensive type 2 diabetic patientsQ58823394
Effects of Picotamide, an Antithromboxane Agent, on Carotid Atherosclerotic EvolutionQ58823405
Synthesis and structure of the platelet aggregation factor thromboxane A2Q59062122
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcirculatory systemQ11068
P304page(s)479-493
P577publication date2009-09-01
P1433published inFuture CardiologyQ15765184
P1476titleEffect of pharmaceutical interventions targeting thromboxane receptors and thromboxane synthase in cardiovascular and renal diseases
P478volume5

Reverse relations

cites work (P2860)
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Q34622554Drug strategies targeting CYP51 in neglected tropical diseases
Q34389439Impact of vascular thromboxane prostanoid receptor activation on hemostasis, thrombosis, oxidative stress, and inflammation.
Q89219277Investigation of a Thromboxane A2 Receptor-Based Vaccine for Managing Thrombogenesis
Q53798598Pharmacodynamic effects of EV-077: results of an in vitro pilot investigation in healthy volunteers.
Q55399934Prostaglandins in the pathogenesis of kidney diseases.
Q46637396Single ascending oral dose pharmacokinetics and pharmacodynamics study of EV-077: the specific inhibitor of prostanoid- and isoprostane-induced cellular activation

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