The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.

scholarly article

The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development. is …
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scholarly articleQ13442814

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P819ADS bibcode2004PNAS..10115201L
P356DOI10.1073/PNAS.0404995101
P932PMC publication ID524058
P698PubMed publication ID15475576
P5875ResearchGate publication ID8239583

P50authorYue FengQ57339435
P2093author name stringWen Li
Li Ku
Zhe Liang
Stephen T Warren
Houping Wang
Robert Lu
William T O'donnell
P2860cites workNew synaptic bouton formation is disrupted by misregulation of microtubule stability in aPKC mutantsQ42144825
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Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and functionQ47071944
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Increased Expression of Microtubule-Associated Protein 1B in the Hippocampus, Subiculum, and Perforant Path of Rats Treated with a High Dose of PentylenetetrazoleQ48586661
Altered mossy fiber distributions in adult Fmr1 (FVB) knockout miceQ48649059
The neuronal microtubule-associated protein 1B is under homeoprotein transcriptional control.Q48874069
Epilepsy in fragile X syndromeQ51952378
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Altered synaptic plasticity in a mouse model of fragile X mental retardationQ24530695
Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficitsQ24657867
Novel features of the light chain of microtubule-associated protein MAP1B: microtubule stabilization, self interaction, actin filament binding, and regulation by the heavy chainQ24670508
FMRP Associates with Polyribosomes as an mRNP, and the I304N Mutation of Severe Fragile X Syndrome Abolishes This AssociationQ28115097
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The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapsesQ28208647
Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathwayQ28236951
Inhibition of GSK-3β leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithiumQ28269508
Differential regulation of microtubule-associated protein 1B (MAP1B) in rat CNS and PNS during developmentQ28570940
Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapsesQ28576233
Attenuation of microtubule-associated protein 1B expression by antisense oligodeoxynucleotides inhibits initiation of neurite outgrowthQ28576269
Developmentally-programmed FMRP expression in oligodendrocytes: a potential role of FMRP in regulating translation in oligodendroglia progenitorsQ28580499
The fragile X mental retardation protein inhibits translation via interacting with mRNAQ28588486
Abnormal development of dendritic spines in FMR1 knock-out miceQ28589950
Fragile X Mental Retardation Protein Targets G Quartet mRNAs Important for Neuronal FunctionQ29616372
Microarray Identification of FMRP-Associated Brain mRNAs and Altered mRNA Translational Profiles in Fragile X SyndromeQ29616495
Selective localization of polyribosomes beneath developing synapses: A quantitative analysis of the relationships between polyribosomes and developing synapses in the hippocampus and dentate gyrusQ30445275
Protein synthesis within dendrites: glycosylation of newly synthesized proteins in dendrites of hippocampal neurons in culture.Q30469206
The microtubule-associated protein MAP1B is involved in local stabilization of turning growth conesQ30836998
Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.Q32063419
The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95Q33717210
MAP1B expression and microtubule stability in growing and regenerating axonsQ33825455
Dendritic spine structural anomalies in fragile-X mental retardation syndromeQ33919487
Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repressionQ34157806
Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes.Q34699414
Actin and microtubules in neurite initiation: Are MAPs the missing link?Q35575876
Microtubule-associated protein 1B function during normal development, regeneration, and pathological conditions in the nervous systemQ35575880
Microtubules and growth cone function.Q35575888
Individual microtubules in the axon consist of domains that differ in both composition and stabilityQ36223418
Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticlesQ37513552
Evidence for the role of MAP1B in axon formationQ39092885
P433issue42
P407language of work or nameEnglishQ1860
P304page(s)15201-15206
P577publication date2004-10-08
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleThe fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development
P478volume101