ZD 7288, an HCN channel blocker, attenuates chronic visceral pain in irritable bowel syndrome-like rats

scientific article published on February 2014

ZD 7288, an HCN channel blocker, attenuates chronic visceral pain in irritable bowel syndrome-like rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3748/WJG.V20.I8.2091
P932PMC publication ID3934480
P698PubMed publication ID24587682

P2093author name stringYing Tang
Yu Chen
Da-Li Lu
Chun Lin
Ai-Qin Chen
Cui-Ying Liu
P2860cites workReview article: new receptor targets for medical therapy in irritable bowel syndromeQ33959307
Neuronal hyperpolarization-activated pacemaker channels drive neuropathic pain.Q34178989
EMERGING THERAPIES AND NOVEL APPROACHES TO VISCERAL PAIN.Q34485671
The roles of sodium channels in nociception: Implications for mechanisms of painQ34674268
HCN channels in behavior and neurological disease: too hyper or not active enough?Q34777401
Visceral pain: the neurophysiological mechanismQ35164413
Differential effects of glutamate receptor antagonists on dorsal horn neurons responding to colorectal distension in a neonatal colon irritation rat modelQ35165975
Electroacupuncture alleviates stress-induced visceral hypersensitivity through an opioid system in ratsQ36529154
Upregulation of cystathionine beta-synthetase expression by nuclear factor-kappa B activation contributes to visceral hypersensitivity in adult rats with neonatal maternal deprivationQ36535880
A synaptic model for pain: long-term potentiation in the anterior cingulate cortex.Q36889909
Characteristics of HCN channels and their participation in neuropathic painQ37156571
A treatment trial of acupuncture in IBS patientsQ37223914
HCN pacemaker channels and pain: a drug discovery perspectiveQ37515967
Erasing injury-related cortical synaptic potentiation as a new treatment for chronic painQ37876337
HCN2 ion channels: an emerging role as the pacemakers of painQ38011927
Current and future pharmacological treatments for diarrhea-predominant irritable bowel syndromeQ38102063
Involvement of hyperpolarization-activated, cyclic nucleotide-gated cation channels in dorsal root ganglion in neuropathic painQ40032451
Pacemaker mechanisms in cardiac tissue.Q40486018
The role of HCN channels within the periaqueductal gray in neuropathic painQ43410418
Spinal hyperpolarization-activated cyclic nucleotide-gated cation channels at primary afferent terminals contribute to chronic painQ44040506
NMDA receptor antagonists attenuate noxious and nonnoxious colorectal distention-induced Fos expression in the spinal cord and the visceromotor reflex.Q44068230
Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord contributes to chronic visceral pain in ratsQ44762084
Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic painQ45815924
Suspended moxibustion relieves chronic visceral hyperalgesia via serotonin pathway in the colonQ46180392
Antinociceptive effect of intra-hippocampal CA1 and dentate gyrus injection of MK801 and AP5 in the formalin test in adult male rats.Q48240343
Long-term sensitization of primary afferents in adult rats exposed to neonatal colon painQ48337628
Effects of neonatal maternal separation on neurochemical and sensory response to colonic distension in a rat model of irritable bowel syndrome.Q48367744
Electro-acupuncture relieves chronic visceral hyperalgesia in rats.Q51237576
HCN2 Ion Channels Play a Central Role in Inflammatory and Neuropathic PainQ58791990
Axonal accumulation of hyperpolarization-activated cyclic nucleotide-gated cation channels contributes to mechanical allodynia after peripheral nerve injury in ratQ60679944
Mechanism of block by ZD 7288 of the hyperpolarization-activated inward rectifying current in guinea pig substantia nigra neurons in vitroQ71365318
Experimental colitis alters visceromotor response to colorectal distension in awake ratsQ72498054
A new model of chronic visceral hypersensitivity in adult rats induced by colon irritation during postnatal developmentQ73130772
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectchronic painQ1088113
P304page(s)2091-2097
P577publication date2014-02-01
P1433published inWorld Journal of GastroenterologyQ15708885
P1476titleZD 7288, an HCN channel blocker, attenuates chronic visceral pain in irritable bowel syndrome-like rats
P478volume20

Reverse relations

cites work (P2860)
Q38376282Animal models of gastrointestinal and liver diseases. Animal models of visceral pain: pathophysiology, translational relevance, and challenges
Q38973036Critical Evaluation of Animal Models of Gastrointestinal Disorders
Q92616981Decreased HCN2 channel expression attenuates neuropathic pain by inhibiting pro-inflammatory reactions and NF-κB activation in mice
Q28087285Early-life stress origins of gastrointestinal disease: animal models, intestinal pathophysiology, and translational implications

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