Galanin stimulates neurite outgrowth from sensory neurons by inhibition of Cdc42 and Rho GTPases and activation of cofilin

scientific article published on August 22, 2013

Galanin stimulates neurite outgrowth from sensory neurons by inhibition of Cdc42 and Rho GTPases and activation of cofilin is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/JNC.12379
P953full work available online athttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fjnc.12379
https://europepmc.org/articles/PMC3935412
https://europepmc.org/articles/PMC3935412?pdf=render
https://onlinelibrary.wiley.com/doi/pdf/10.1111/jnc.12379
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.12379
P932PMC publication ID3935412
P698PubMed publication ID23895321
P5875ResearchGate publication ID253337453

P2093author name stringDavid Wynick
Sally-Ann Hobson
Robert J. P. Pope
Niall C. H. Kerr
Penny A. Vanderplank
P2860cites workSignaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinaseQ22010473
Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamicsQ22010790
A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPasesQ24304128
Molecular cloning of a functional human galanin receptorQ24306226
Cloned human and rat galanin GALR3 receptors. Pharmacology and activation of G-protein inwardly rectifying K+ channelsQ24309179
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factorQ24561804
Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2Q24670491
Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarityQ24682414
The small GTP-binding protein rac regulates growth factor-induced membrane rufflingQ27861063
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodiaQ27861126
Influencing cellular transformation by modulating the rates of GTP hydrolysis by Cdc42Q28246939
A brain serine/threonine protein kinase activated by Cdc42 and Rac1Q28249559
DSCR1 interacts with FMRP and is required for spine morphogenesis and local protein synthesisQ28506537
Differential Intracellular Signaling of the GalR1 and GalR2 Galanin Receptor SubtypesQ28582628
The second galanin receptor GalR2 plays a key role in neurite outgrowth from adult sensory neuronsQ28584796
Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinaseQ29614246
The role of the Rho GTPases in neuronal developmentQ29616295
Proteins of the ADF/cofilin family: essential regulators of actin dynamicsQ29618546
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeletonQ29620156
Rho GTPases in neuronal morphogenesisQ29620432
Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cellsQ30476210
Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory networkQ30483613
Regulating actin-filament dynamics in vivoQ33818810
Regulating actin dynamics in neuronal growth cones by ADF/cofilin and rho family GTPasesQ33996735
ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticityQ34163910
Galanin in sensory neurons in the spinal cordQ35156448
Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacityQ35320080
Estrogen receptor-dependent regulation of sensory neuron survival in developing dorsal root ganglionQ35637004
Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin.Q36162667
Distribution and cellular localization of actin depolymerizing factorQ36217103
Isolation and characterization of a regulated form of actin depolymerizing factorQ36232804
Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acidQ36565713
Neural plasticity after peripheral nerve injury and regenerationQ36887919
Ins and outs of ADF/cofilin activity and regulationQ37171388
Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain-like behaviourQ37302332
Rho GTPases as regulators of morphological neuroplasticityQ37860720
Specificity of peripheral nerve regeneration: interactions at the axon levelQ38011492
Galanin and galanin-like peptide modulate neurite outgrowth via protein kinase C-mediated activation of extracellular signal-related kinaseQ40259271
Messenger plasticity in primary sensory neurons following axotomy and its functional implicationsQ40387628
Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11.Q40644445
Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assemblyQ40689626
Potent activation of RhoA by Galpha q and Gq-coupled receptors.Q40730965
Actin depolymerizing factor and cofilin phosphorylation dynamics: Response to signals that regulate neurite extensionQ41062789
Effects of glial cell line-derived neurotrophic factor on axonal growth and apoptosis in adult mammalian sensory neurons in vitroQ41065138
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.Q41450596
Regulation of Dendritic Growth and Remodeling by Rho, Rac, and Cdc42Q42445511
Targeted disruption of the murine galanin gene.Q42467296
The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteinsQ42797552
Cdc42 is a Rho GTPase family member that can mediate insulin signaling to glucose transport in 3T3-L1 adipocytesQ42805625
Histamine acting on H1 receptor promotes inhibition of proliferation via PLC, RAC, and JNK-dependent pathwaysQ43242549
Increase in neurite outgrowth mediated by overexpression of actin depolymerizing factor.Q43503737
Cdc42 stimulates neurite outgrowth and formation of growth cone filopodia and lamellipodiaQ43532192
Independent roles of Rho-GTPases in growth cone and axonal behaviorQ44261292
p75 neurotrophin receptor signaling regulates growth cone filopodial dynamics through modulating RhoA activity.Q44885110
Brain-derived neurotrophic factor regulation of retinal growth cone filopodial dynamics is mediated through actin depolymerizing factor/cofilin.Q45163168
Cdc42 participates in the regulation of ADF/cofilin and retinal growth cone filopodia by brain derived neurotrophic factorQ46744846
Cdc42 regulates cofilin during the establishment of neuronal polarity.Q46876551
Growth cone pathfinding and filopodial dynamics are mediated separately by Cdc42 activation.Q47070762
Neuronal polarization is impaired in mice lacking RhoE expressionQ48608412
Decreased cofilin1 expression is important for compaction during early mouse embryo developmentQ51926368
miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathwayQ54287457
The axotomy-induced neuropeptides galanin and pituitary adenylate cyclase-activating peptide promote axonal sprouting of primary afferent and cranial motor neuronesQ62573915
Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomyQ69020728
Reactivation of phosphorylated actin depolymerizing factor and identification of the regulatory siteQ71892123
Inactivation of Rho signaling pathway promotes CNS axon regenerationQ78166417
LIM kinase and slingshot are critical for neurite extensionQ79951658
Growth cone responses to growth and chemotropic factorsQ81783038
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectneuriteQ1534415
P304page(s)199-208
P577publication date2013-08-22
P1433published inJournal of NeurochemistryQ6295643
P1476titleGalanin stimulates neurite outgrowth from sensory neurons by inhibition of Cdc42 and Rho GTPases and activation of cofilin
P478volume127

Reverse relations

cites work (P2860)
Q45033705Alpha 7 nicotinic receptor coupling to heterotrimeric G proteins modulates RhoA activation, cytoskeletal motility, and structural growth
Q39434514Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury
Q37508163Epigenetic profiling reveals a developmental decrease in promoter accessibility during cortical maturation in vivo
Q27305173Galanin mediates features of neural and behavioral stress resilience afforded by exercise
Q38556483Galanin receptors as a potential target for neurological disease.
Q38703954Neurite Outgrowth Stimulated by Oxytocin Is Modulated by Inhibition of the Calcium Voltage-Gated Channels
Q38827379Oxytocin Increases Neurite Length and Expression of Cytoskeletal Proteins Associated with Neuronal Growth.
Q36922331Regulation of neurological and neuropsychiatric phenotypes by locus coeruleus-derived galanin
Q36159591The generation of knock-in mice expressing fluorescently tagged galanin receptors 1 and 2.
Q34433485Trophic Mechanisms for Exercise-Induced Stress Resilience: Potential Role of Interactions between BDNF and Galanin

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