Selectins and their ligands are required for homing and engraftment of BCR-ABL1+ leukemic stem cells in the bone marrow niche

scientific article published on 06 January 2014

Selectins and their ligands are required for homing and engraftment of BCR-ABL1+ leukemic stem cells in the bone marrow niche is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2013-11-538694
P932PMC publication ID3938148
P698PubMed publication ID24394666
P5875ResearchGate publication ID259606804

P50authorUlrich von AndrianQ7879876
P2093author name stringKatherine Lazarides
Richard A Van Etten
Daniela S Krause
Juliana B Lewis
P2860cites workImproved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent proteinQ27861056
Interferon-alpha restores normal beta 1 integrin-mediated inhibition of hematopoietic progenitor proliferation by the marrow microenvironment in chronic myelogenous leukemiaQ71029701
BCR/ABL-negative primitive progenitors suitable for transplantation can be selected from the marrow of most early-chronic phase but not accelerated-phase chronic myelogenous leukemia patientsQ71099947
In vitro purging with BCR-ABL antisense oligodeoxynucleotides does not prevent haematologic reconstitution after autologous bone marrow transplantationQ71689335
A central role for microvillous receptor presentation in leukocyte adhesion under flowQ71729689
Restoration of nonclonal hematopoiesis in chronic myelogenous leukemia (CML) following a chemotherapy-induced loss of the Ph1 chromosomeQ71983896
Autografting with cultured marrow in chronic myeloid leukemia: results of a pilot studyQ72090448
PSGL-1-mediated adhesion of human hematopoietic progenitors to P-selectin results in suppression of hematopoiesisQ73065694
The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID miceQ73827359
Platelet-endothelial interactions in inflamed mesenteric venulesQ74138198
Autografting with philadelphia chromosome-negative mobilized hematopoietic progenitor cells in chronic myelogenous leukemiaQ74462961
Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4Q77952550
Leukocyte migration is regulated by L-selectin endoproteolytic releaseQ79291240
P-selectin glycoprotein ligand-1 mediates L-selectin-dependent leukocyte rolling in venulesQ30310860
P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flowQ30453100
Autologous transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia achieves outcomes similar to allogeneic transplantation: results of CALGB Study 10001 (Alliance).Q33558183
The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleenQ33859887
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemiaQ34183674
How do stem cells find their way home?Q34418463
Deletion of alpha4 integrins from adult hematopoietic cells reveals roles in homeostasis, regeneration, and homing.Q34988228
Bone marrow homing: the players, the playfield, and their evolving rolesQ35104924
Glycan-dependent leukocyte adhesion and recruitment in inflammationQ35547358
A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic cellsQ35578307
Autologous hematopoietic cell transplantation for chronic myelogenous leukemiaQ35844188
Hierarchy of molecular-pathway usage in bone marrow homing and its shift by cytokines.Q35848474
A cell-autonomous requirement for CXCR4 in long-term lymphoid and myeloid reconstitutionQ36363874
Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrowQ36369274
Hematopoietic progenitor cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and vascular cell adhesion molecule 1.Q36401478
Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrowQ36735787
VLA-5 is expressed by mouse and human long-term repopulating hematopoietic cells and mediates adhesion to extracellular matrix protein fibronectinQ37385089
An sLex-deficient variant of HL60 cells exhibits high levels of adhesion to vascular selectins: further evidence that HECA-452 and CSLEX1 monoclonal antibody epitopes are not essential for high avidity binding to vascular selectins.Q38337581
Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cellsQ40228137
Oligodeoxynucleotide-mediated inhibition of c-myb gene expression in autografted bone marrow: a pilot studyQ40662091
L-selectin expression in CD34 positive cells in chronic myeloid leukemiaQ41727888
Differential requirements for the O-linked branching enzyme core 2 beta1-6-N-glucosaminyltransferase in biosynthesis of ligands for E-selectin and P-selectinQ43627732
The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homingQ43695970
Molecular pathways in bone marrow homing: dominant role of alpha(4)beta(1) over beta(2)-integrins and selectinsQ43757332
Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitroQ43833442
Imatinib restores expression of CD62L in BCR-ABL-positive cellsQ44417197
PSGL-1 participates in E-selectin-mediated progenitor homing to bone marrow: evidence for cooperation between E-selectin ligands and alpha4 integrin.Q44451874
Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cellsQ44471784
Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML.Q45072562
Gene therapy to target dendritic cells from blood to lymph nodesQ45864389
Immature leukemic CD34+CXCR4+ cells from CML patients have lower integrin-dependent migration and adhesion in response to the chemokine SDF-1.Q45885744
Lack of the adhesion molecules P-selectin and intercellular adhesion molecule-1 accelerate the development of BCR/ABL-induced chronic myeloid leukemia-like myeloproliferative disease in miceQ47303224
Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cellsQ47781655
CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrowQ47800956
CD44-deficient mice develop normally with changes in subpopulations and recirculation of lymphocyte subsets.Q52173790
Interleukin 3 and granulocyte-macrophage colony-stimulating factor are not required for induction of chronic myeloid leukemia-like myeloproliferative disease in mice by BCR/ABL.Q53401270
The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha.Q53416308
Autologous stem cell transplantation in chronic myeloid leukemia: a single center experience.Q54081707
Kinetics of in vivo homing and recruitment into cycle of hematopoietic cells are organ-specific but CD44-independent.Q54457002
Beta1 integrin is not essential for hematopoiesis but is necessary for the T cell-dependent IgM antibody responseQ57510587
Fetal and adult hematopoietic stem cells require beta1 integrin function for colonizing fetal liver, spleen, and bone marrowQ57510593
The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand BiosynthesisQ60719538
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
bone marrowQ546523
P304page(s)1361-1371
P577publication date2014-01-06
P1433published inBloodQ885070
P1476titleSelectins and their ligands are required for homing and engraftment of BCR-ABL1+ leukemic stem cells in the bone marrow niche
P478volume123

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