Macromolecular crowding amplifies adipogenesis of human bone marrow-derived mesenchymal stem cells by enhancing the pro-adipogenic microenvironment

scientific article published on 03 December 2013

Macromolecular crowding amplifies adipogenesis of human bone marrow-derived mesenchymal stem cells by enhancing the pro-adipogenic microenvironment is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1089/TEN.TEA.2013.0337
P932PMC publication ID3938936
P698PubMed publication ID24147829

P50authorAnna BlockiQ57083251
P2093author name stringMichael Raghunath
H Harry Asada
Allan Sheppard
Clarice Chen
L L Sharon Ong
Michelle H C Lee
Xiu Min Ang
P2860cites workUnderstanding adipocyte differentiationQ46119331
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Protein concentration of lymph and interstitial fluid in the rat tailQ71416071
Change in macromolecular composition of interstitial fluid from swollen arms after breast cancer treatment, and its implicationsQ72722851
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Plasma protein concentration of normal adults living in SingaporeQ73326529
Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinasesQ81168941
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Molecular crowding enhances native state stability and refolding rates of globular proteinsQ33935100
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Socializing with the neighbors: stem cells and their nicheQ34307665
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Metalloproteases and adipogenesis: a weighty subjectQ35748020
Tissue-engineered skin substitutes: from in vitro constructs to in vivo applicationsQ35779014
Adult bone marrow stem/progenitor cells (MSCs) are preconditioned by microenvironmental "niches" in culture: a two-stage hypothesis for regulation of MSC fate.Q36208443
Nile red: a selective fluorescent stain for intracellular lipid dropletsQ36211849
Macromolecular crowding effect on cartilaginous matrix production: a comparison of two-dimensional and three-dimensional modelsQ36947666
The Scar-in-a-Jar: studying potential antifibrotic compounds from the epigenetic to extracellular level in a single well.Q37434404
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Applying macromolecular crowding to enhance extracellular matrix deposition and its remodeling in vitro for tissue engineering and cell-based therapies.Q37851632
Collagen matrix deposition is dramatically enhanced in vitro when crowded with charged macromolecules: the biological relevance of the excluded volume effect.Q40127292
In vitro enhancement of collagen matrix formation and crosslinking for applications in tissue engineering: a preliminary study.Q40129393
Macromolecular crowding: biochemical, biophysical, and physiological consequencesQ40488946
Adipocyte produces matrix metalloproteinases 2 and 9: involvement in adipose differentiationQ40783644
Bone morphogenetic proteins inhibit adipocyte differentiation by bone marrow stromal cellsQ41331286
Influence of excluded volume upon macromolecular structure and associations in 'crowded' mediaQ41334318
Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-adipocytesQ42820082
Autocrine fibroblast growth factor 2-mediated interactions between human mesenchymal stem cells and the extracellular matrix under varying oxygen tensionQ43766104
Elongation of actin filaments is a diffusion-limited reaction at the barbed end and is accelerated by inert macromolecules.Q45242019
P433issue5-6
P921main subjectbone marrowQ546523
adipogenesisQ2824461
macromoleculeQ178593
P304page(s)966-981
P577publication date2013-12-03
P1433published inTissue Engineering. Part AQ15758518
P1476titleMacromolecular crowding amplifies adipogenesis of human bone marrow-derived mesenchymal stem cells by enhancing the pro-adipogenic microenvironment
P478volume20

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Q39217163A Review of Cell-Based Strategies for Soft Tissue Reconstruction
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Q51176024Improving 2D and 3D Skin In Vitro Models Using Macromolecular Crowding.
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Q37141160Macromolecular crowding meets oxygen tension in human mesenchymal stem cell culture - A step closer to physiologically relevant in vitro organogenesis.
Q42375621Making microenvironments: A look into incorporating macromolecular crowding into in vitro experiments, to generate biomimetic microenvironments which are capable of directing cell function for tissue engineering applications
Q34942129Making more matrix: enhancing the deposition of dermal-epidermal junction components in vitro and accelerating organotypic skin culture development, using macromolecular crowding
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