New treatment options for metastatic renal cell carcinoma with prior anti-angiogenesis therapy

scientific article published on 02 February 2017

New treatment options for metastatic renal cell carcinoma with prior anti-angiogenesis therapy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1083412081
P356DOI10.1186/S13045-016-0374-Y
P932PMC publication ID5288948
P698PubMed publication ID28153029

P2093author name stringShenhong Wu
Chunhui Fang
Kevin Zarrabi
P2860cites workTargeting tumorigenesis: development and use of mTOR inhibitors in cancer therapyQ21198871
Immunotherapy for advanced renal cell cancerQ24246777
mTOR inhibitors in advanced renal cell carcinomaQ24612127
Axitinib for the management of metastatic renal cell carcinomaQ24613720
Current status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapyQ26745516
Renal cell carcinoma: links and risksQ26750417
Sequence of treatment in locally advanced and metastatic renal cell carcinomaQ26773653
Metastatic Renal Cell Cancer: Summary from ASCO 2015Q26796392
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasionQ28131654
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinomaQ28247085
Sorafenib in advanced clear-cell renal-cell carcinomaQ28282767
Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trialQ29615711
A small molecule-kinase interaction map for clinical kinase inhibitorsQ29617451
Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trialQ29618031
Identification of the von Hippel-Lindau disease tumor suppressor geneQ29618644
Pazopanib versus sunitinib in metastatic renal-cell carcinomaQ33409916
Axitinib versus sorafenib in advanced renal cell carcinoma: subanalyses by prior therapy from a randomised phase III trialQ33750154
Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206Q33813718
Renal cancer.Q50941188
[Combination of Targeted Therapy and Immunotherapy for Cancer].Q52909682
[Therapy of untreated local advanced or metastatic renal cell carcinoma. Phase III, randomized, open-label study of nivolumab combined with ipilimumab versus sunitinib monotherapy in subjects with previously untreated, local advanced or metastatic rQ53352740
Prescribing Preferences in the First-Line Treatment for Patients With Metastatic Renal Cell Carcinoma in the United States.Q54192985
Renal-cell carcinoma--molecular pathways and therapies.Q55042930
Lenvatinib, everolimus, and the combination in patients with metastatic renal cell carcinoma: a randomised, phase 2, open-label, multicentre trialQ59571527
Long-term follow-up of patients with metastatic renal cell carcinoma treated with intravenous recombinant interleukin-2 in EuropeQ73471160
Nivolumab: The New Second Line Treatment for Advanced Renal-cell Carcinoma Commentary on: Nivolumab Versus Everolimus in Advanced Renal-cell CarcinomaQ87001514
Recent developments in second and third line therapy of metastatic renal cell carcinomaQ87508846
Fibroblast growth factor receptors as therapeutic targets in clear-cell renal cell carcinoma.Q38175454
Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexityQ38214357
Update on the treatment of metastatic clear cell and non-clear cell renal cell carcinomaQ38367115
Safety and Efficacy of Nivolumab in Patients With Metastatic Renal Cell Carcinoma Treated Beyond Progression: A Subgroup Analysis of a Randomized Clinical TrialQ38391922
A Phase II Trial of the Multitargeted Tyrosine Kinase Inhibitor Lenvatinib (E7080) in Advanced Medullary Thyroid CancerQ38574759
Immunotherapy Combined or Sequenced With Targeted Therapy in the Treatment of Solid Tumors: Current PerspectivesQ38721253
Emerging therapeutics in refractory renal cell carcinomaQ38816892
Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinomaQ38835745
Impact of O6-methylguanine-DNA methyltransferase expression on the drug resistance of clear cell renal cell carcinomaQ38851881
Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial.Q38859789
Everolimus versus sunitinib for patients with metastatic non-clear cell renal cell carcinoma (ASPEN): a multicentre, open-label, randomised phase 2 trial.Q38917870
Adjuvant Sunitinib in High-Risk Renal-Cell Carcinoma after NephrectomyQ38975732
Commentary on: "Randomized, controlled, double-blind, cross-over trial assessing treatment preference for pazopanib versus sunitinib in patients with metastatic renal cell carcinoma: PISCES study." Escudier B, Porta C, Bono P, Powles T, Eisen T, SteQ40981962
Nivolumab versus Everolimus in Advanced Renal-Cell CarcinomaQ41316099
Treatment Beyond Progression: Is It Moving from Belief to Evidence?Q42995231
Kinase inhibition with BAY 43-9006 in renal cell carcinomaQ45077916
Randomized phase II trial of first-line treatment with sorafenib versus interferon Alfa-2a in patients with metastatic renal cell carcinomaQ45264009
Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial.Q46006772
E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibitionQ46944486
Quality of life in patients with advanced renal cell carcinoma given nivolumab versus everolimus in CheckMate 025: a randomised, open-label, phase 3 trialQ33922560
Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survivalQ34021957
Bevacizumab demonstrates prolonged disease stabilization in patients with heavily pretreated metastatic renal cell carcinoma: a case series and review of the literatureQ34034222
Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.Q34217927
A randomised, double-blind phase III study of pazopanib in patients with advanced and/or metastatic renal cell carcinoma: final overall survival results and safety update.Q34322740
Cabozantinib versus Everolimus in Advanced Renal-Cell CarcinomaQ34495684
Sunitinib in patients with metastatic renal cell carcinomaQ34568166
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trialQ34586436
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial.Q34633525
Chemotherapy in metastatic renal cell carcinoma today? A systematic reviewQ34650032
Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trialQ34650664
The prospects of pazopanib in advanced renal cell carcinomaQ34656393
Randomized phase III trial of temsirolimus versus sorafenib as second-line therapy after sunitinib in patients with metastatic renal cell carcinoma.Q34658095
Randomized, controlled, double-blind, cross-over trial assessing treatment preference for pazopanib versus sunitinib in patients with metastatic renal cell carcinoma: PISCES StudyQ34660897
Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapyQ34723863
Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivoQ35235365
EAU guidelines on renal cell carcinoma: 2014 update.Q35548292
Will mTOR inhibitors make it as cancer drugs?Q35604822
A phase I study of E7080, a multitargeted tyrosine kinase inhibitor, in patients with advanced solid tumoursQ35949539
Nivolumab versus Cabozantinib: Comparing Overall Survival in Metastatic Renal Cell CarcinomaQ36043473
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancerQ36509678
New strategies in renal cell carcinoma: targeting the genetic and metabolic basis of diseaseQ36696610
Implications of B7-H1 expression in clear cell carcinoma of the kidney for prognostication and therapyQ36718954
Opportunities and obstacles to combination targeted therapy in renal cell cancer.Q36718987
Nivolumab for Metastatic Renal Cell Carcinoma: Results of a Randomized Phase II TrialQ36726204
mTOR signalling in human cancerQ36919646
Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumorsQ37069569
Phase II trial of second-line everolimus in patients with metastatic renal cell carcinoma (RECORD-4)Q37220273
Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics.Q37350230
Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell CarcinomaQ37409862
A phase 1b clinical trial of the multi-targeted tyrosine kinase inhibitor lenvatinib (E7080) in combination with everolimus for treatment of metastatic renal cell carcinoma (RCC).Q37470131
Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathwayQ38078784
Axitinib versus sorafenib as first-line therapy in patients with metastatic renal-cell carcinoma: a randomised open-label phase 3 trialQ38160956
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectangiogenesisQ539568
angiogenesis inhibitorQ574834
renal cell carcinomaQ1164529
kidney neoplasmQ13641482
metastatic renal cell carcinomaQ19000948
investigational therapyQ73510198
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)38
P577publication date2017-02-02
P1433published inJournal of Hematology & OncologyQ15724593
P1476titleNew treatment options for metastatic renal cell carcinoma with prior anti-angiogenesis therapy
P478volume10

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cites work (P2860)
Q89849302A Case Report with Severe Thrombocytopenia Induced by Axitinib
Q38662419A Phase II Multi-Center Study of Bevacizumab in Combination with Ixabepilone in Subjects with Advanced Renal Cell Carcinoma
Q48226648A clinical trial design using the concept of proportional time using the generalized gamma ratio distribution.
Q52611170Current and Emerging Therapeutic Targets for Metastatic Renal Cell Carcinoma.
Q57598537Effect of Targeted Therapies on Prognostic Factors, Patterns of Care, and Survival in Patients With Renal Cell Carcinoma and Brain Metastases
Q93104008Emerging therapeutic agents for genitourinary cancers
Q41573990Hypertension Caused by Lenvatinib and Everolimus in the Treatment of Metastatic Renal Cell Carcinoma.
Q93208369Knockdown of ALPK2 blocks development and progression of renal cell carcinoma
Q44631161Lingual metastasis as an initial presentation of renal cell carcinoma: a case report
Q93017711MicroRNA-486-5p and microRNA-486-3p: Multifaceted pleiotropic mediators in oncological and non-oncological conditions
Q47703386MicroRNAs in cancer metastasis and angiogenesis
Q59793924Mutated Von Hippel-Lindau-renal cell carcinoma (RCC) promotes patients specific natural killer (NK) cytotoxicity
Q47813600Network meta-analysis of second-line treatment in metastatic renal cell carcinoma: efficacy and safety
Q64103672Recent advances on anti-angiogenesis receptor tyrosine kinase inhibitors in cancer therapy
Q89393258Resistance to Systemic Therapies in Clear Cell Renal Cell Carcinoma: Mechanisms and Management Strategies
Q92977454Second line therapy with axitinib after only prior sunitinib in metastatic renal cell cancer: Italian multicenter real world SAX study final results
Q91844057Sunitinib for Metastatic Renal Cell Carcinoma: A Systematic Review and Meta-Analysis of Real-World and Clinical Trials Data
Q50078523Tumor Microvessel Density as a Prognostic Marker in High-Risk Renal Cell Carcinoma Patients Treated on ECOG-ACRIN E2805.

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