The extracellular regulation of bone morphogenetic protein signaling

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The extracellular regulation of bone morphogenetic protein signaling is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1242/DEV.031534
P932PMC publication ID2766339
P698PubMed publication ID19855014
P5875ResearchGate publication ID38034456

P2093author name stringMichael B O'Connor
Seth S Blair
David Umulis
P2860cites workGlypicansQ21183908
DRAGON, a bone morphogenetic protein co-receptorQ24292739
Glypican LON-2 is a conserved negative regulator of BMP-like signaling in Caenorhabditis elegansQ24293743
Bone morphogenetic proteins signal through the transforming growth factor-beta type III receptorQ24306137
BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesisQ24312066
Biglycan is a new extracellular component of the Chordin-BMP4 signaling pathwayQ24529120
GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cellsQ24531973
BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-IIQ24631766
A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7Q24653867
The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signallingQ24656491
BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiationQ24679290
Regulation of limb patterning by extracellular microfibrilsQ24685602
Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligandQ27649251
Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor bindingQ27650592
Targeting of bone morphogenetic protein growth factor complexes to fibrillinQ28118178
Identification of the ligand-binding site of the BMP type IA receptor for BMP-4Q28203953
Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradientsQ28204970
Homologues of Twisted gastrulation are extracellular cofactors in antagonism of BMP signallingQ28205891
Lipoprotein particles are required for Hedgehog and Wingless signallingQ28248673
BMP antagonists: their roles in development and involvement in pathophysiologyQ28255986
TGFbeta family signaling: novel insights in development and diseaseQ28262452
Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosisQ28279926
The Twisted gastrulation family of proteins, together with the IGFBP and CCN families, comprise the TIC superfamily of cysteine rich secreted factorsQ28360508
glypican-3 controls cellular responses to Bmp4 in limb patterning and skeletal developmentQ28507693
Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic diseaseQ28508295
Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptorQ28510682
Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordinQ28512603
HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradientQ28609767
Evo-devo: variations on ancestral themesQ28755209
Positional information and the spatial pattern of cellular differentiationQ29616635
Analysis of dynamic morphogen scale invarianceQ41832321
Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation in BMP signalingQ41835575
Mouse Crossveinless-2 is the vertebrate homolog of a Drosophila extracellular regulator of BMP signalingQ41850839
Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryosQ41858943
The endocytic pathway and formation of the Wingless morphogen gradientQ42487988
Elucidation of subfamily segregation and intramolecular coevolution of the olfactomedin-like proteins by comprehensive phylogenetic analysis and gene expression pattern assessment.Q42670137
Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface.Q43029966
Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic fieldQ43073793
The BMP signaling gradient patterns dorsoventral tissues in a temporally progressive manner along the anteroposterior axisQ43074864
dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activityQ43138530
Crossveinless-2 Is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterningQ43244356
Type IV collagens and Dpp: positive and negative regulators of signalingQ44257725
Vertebrate crossveinless 2 is secreted and acts as an extracellular modulator of the BMP signaling cascadeQ44930072
Silencing of TGF-beta signalling by the pseudoreceptor BAMBI.Q45345819
Combinatorial signaling by Twisted Gastrulation and Decapentaplegic.Q46019495
On the role of glypicans in the process of morphogen gradient formationQ46050552
Creation of a Sog morphogen gradient in the Drosophila embryoQ46099920
The Drosophila decapentaplegic and short gastrulation genes function antagonistically during adult wing vein development.Q46182535
Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathwaysQ46222991
Regulation of BMP-induced ectopic bone formation by AhsgQ46483432
Do morphogen gradients arise by diffusion?Q46502677
Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation geneQ46783591
Knockdown of zebrafish crim1 results in a bent tail phenotype with defects in somite and vascular developmentQ46981063
Type IV collagens regulate BMP signalling in DrosophilaQ47070333
Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycansQ47070505
Regulation of dally, an integral membrane proteoglycan, and its function during adult sensory organ formation of DrosophilaQ47070527
Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activityQ47070543
Matching catalytic activity to developmental function: tolloid-related processes Sog in order to help specify the posterior crossvein in the Drosophila wingQ47071229
Long-range Dpp signaling is regulated to restrict BMP signaling to a crossvein competent zone.Q47071235
Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryoQ47071657
Crossveinless 2 contains cysteine-rich domains and is required for high levels of BMP-like activity during the formation of the cross veins in DrosophilaQ47071708
Gradient formation of the TGF-beta homolog Dpp.Q47071783
Dpp gradient formation in the Drosophila wing imaginal discQ47072140
Expression of a secreted form of Dally, a Drosophila glypican, induces overgrowth phenotype by affecting action range of HedgehogQ47072245
Crossveinless 2 is an essential positive feedback regulator of Bmp signaling during zebrafish gastrulationQ47074038
crm-1 facilitates BMP signaling to control body size in Caenorhabditis elegansQ47270276
Physical properties of Tld, Sog, Tsg and Dpp protein interactions are predicted to help create a sharp boundary in Bmp signals during dorsoventral patterning of the Drosophila embryoQ47681453
DRAGON, a GPI-anchored membrane protein, inhibits BMP signaling in C2C12 myoblastsQ47862467
Anti-dorsalizing morphogenetic protein is a novel TGF-beta homolog expressed in the Spemann organizerQ48068846
Lipoprotein-heparan sulfate interactions in the Hh pathwayQ50336941
Mammalian Notum induces the release of glypicans and other GPI-anchored proteins from the cell surfaceQ50336949
Syndecan-1 regulates BMP signaling and dorso-ventral patterning of the ectoderm during early Xenopus development.Q51756884
Kinetics of morphogen gradient formation.Q51924455
The mechanism of sudden stripe formation during dorso-ventral patterning in Drosophila.Q51928749
Twisted gastrulation mutation suppresses skeletal defect phenotypes in Crossveinless 2 mutant mice.Q51952135
Heparan sulfate proteoglycans at a glance.Q51985397
Crim1KST264/KST264 mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development.Q51987898
Tolloid gets Sizzled competing with Chordin.Q52026716
Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans.Q52086756
A vertebrate crossveinless 2 homologue modulates BMP activity and neural crest cell migration.Q52087210
Robustness of the BMP morphogen gradient in Drosophila embryonic patterning.Q52114692
Follistatin regulates bone morphogenetic protein-7 (BMP-7) activity to stimulate embryonic muscle growth.Q52123833
Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginal disc.Q52182365
Dpp gradient formation by dynamin-dependent endocytosis: receptor trafficking and the diffusion model.Q52650937
The crossveinless gene encodes a new member of the Twisted gastrulation family of BMP-binding proteins which, with Short gastrulation, promotes BMP signaling in the crossveins of the Drosophila wing.Q52657937
α2-HS Glycoprotein/Fetuin, a Transforming Growth Factor-β/Bone Morphogenetic Protein Antagonist, Regulates Postnatal Bone Growth and RemodelingQ56999751
Scaling of the BMP activation gradient in Xenopus embryosQ59064240
Modulation of the binding of matrix Gla protein (MGP) to bone morphogenetic protein-2 (BMP-2)Q73387646
Site-specific interaction of bone morphogenetic protein 2 with procollagen IIQ74484057
Mechanisms for positional signalling by morphogen transport: a theoretical studyQ74567323
von Willebrand factor type C domain-containing proteins regulate bone morphogenetic protein signaling through different recognition mechanismsQ80273766
Heparan sulfate proteoglycans including syndecan-3 modulate BMP activity during limb cartilage differentiationQ81354471
Bmp signaling: turning a half into a wholeQ81636894
Order out of chaos: assembly of ligand binding sites in heparan sulfateQ29620085
The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptorsQ30052356
crossveinless defines a new family of Twisted-gastrulation-like modulators of bone morphogenetic protein signallingQ30982795
Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin.Q33206751
BMP stimulation of alkaline phosphatase activity in pluripotent mouse C2C12 cells is inhibited by dermatopontin, one of the most abundant low molecular weight proteins in demineralized bone matrixQ33264254
Synergistic effects of Nell-1 and BMP-2 on the osteogenic differentiation of myoblastsQ33835530
Why cytoplasmic signalling proteins should be recruited to cell membranes.Q33885449
Spemann's organizer and self-regulation in amphibian embryosQ33993579
Action range of BMP is defined by its N-terminal basic amino acid coreQ34113614
CRIM1 regulates the rate of processing and delivery of bone morphogenetic proteins to the cell surface.Q34205739
Domain-specific modification of heparan sulfate by Qsulf1 modulates the binding of the bone morphogenetic protein antagonist NogginQ34279840
Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteinsQ34295177
Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transductionQ34315554
A common plan for dorsoventral patterning in BilateriaQ34374917
Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activityQ34445698
A translational block to HSPG synthesis permits BMP signaling in the early Drosophila embryoQ34454099
Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinasesQ34484724
Robust, bistable patterning of the dorsal surface of the Drosophila embryoQ34550702
Bone morphogenetic proteins and their antagonistsQ34572394
Crim1KST264/KST264 mice display a disruption of the Crim1 gene resulting in perinatal lethality with defects in multiple organ systemsQ34581812
Chordin-like CR domains and the regulation of evolutionarily conserved extracellular signaling systems.Q34626087
The cysteine-rich domain protein KCP is a suppressor of transforming growth factor beta/activin signaling in renal epitheliaQ34718144
Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinasesQ34792315
Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulatorsQ34958533
Comparative Genomic Analysis of the Eight-Membered Ring Cystine Knot-Containing Bone Morphogenetic Protein AntagonistsQ35549994
Crossveinless-2 controls bone morphogenetic protein signaling during early cardiomyocyte differentiation in P19 cellsQ35674506
Formation of the BMP activity gradient in the Drosophila embryoQ35690799
Wingful, an extracellular feedback inhibitor of WinglessQ35776013
Molecular recognition in bone morphogenetic protein (BMP)/receptor interactionQ35902283
Interpreting clone-mediated perturbations of morphogen profiles.Q36008793
Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryoQ36257576
Type IIA procollagen containing the cysteine-rich amino propeptide is deposited in the extracellular matrix of prechondrogenic tissue and binds to TGF-beta1 and BMP-2.Q36288339
Shaping BMP morphogen gradients in the Drosophila embryo and pupal wing.Q36348381
The interpretation of morphogen gradientsQ36367278
Quantitative models of developmental pattern formationQ36584506
Extracellular modulation of BMP activity in patterning the dorsoventral axis.Q36633269
Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting systemQ36638792
Morpheus unbound: reimagining the morphogen gradientQ36718804
Tinkering with heparan sulfate sulfation to steer developmentQ36744373
Xenopus kielin: A dorsalizing factor containing multiple chordin-type repeats secreted from the embryonic midline.Q36970265
Robustness of embryonic spatial patterning in Drosophila melanogaster.Q37006654
Theoretical and experimental approaches to understand morphogen gradientsQ37118479
A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signalingQ37124350
BMPER is a conserved regulator of hematopoietic and vascular development in zebrafishQ37258951
Interaction between proteins localized in membranesQ37396417
Informatics approaches to understanding TGFbeta pathway regulation.Q37397518
Bone morphogenetic protein-2 activity is regulated by secreted phosphoprotein-24 kd, an extracellular pseudoreceptor, the gene for which maps to a region of the human genome important for bone qualityQ37449764
The regulation of TGFbeta signal transductionQ37621155
Twisted gastrulation is a conserved extracellular BMP antagonistQ38303086
Essential pro-Bmp roles of crossveinless 2 in mouse organogenesisQ38308645
Sizzled controls dorso-ventral polarity by repressing cleavage of the Chordin proteinQ38315245
Cerberus functions as a BMP agonist to synergistically induce nodal expression during left-right axis determination in the chick embryo.Q39921132
Robust stability of the embryonic axial pattern requires a secreted scaffold for chordin degradationQ39942706
Amelogenin binds to both heparan sulfate and bone morphogenetic protein 2 and pharmacologically suppresses the effect of noggin.Q39976665
Proline and gamma-carboxylated glutamate residues in matrix Gla protein are critical for binding of bone morphogenetic protein-4.Q39998162
Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted GastrulationQ40047807
HSPG modulation of BMP signaling in fibrodysplasia ossificans progressiva cellsQ40129950
The function of a Drosophila glypican does not depend entirely on heparan sulfate modificationQ40217255
The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrixQ40414698
Spatial bistability of Dpp-receptor interactions during Drosophila dorsal-ventral patterning.Q40439096
The BMP-binding protein Crossveinless 2 is a short-range, concentration-dependent, biphasic modulator of BMP signaling in Drosophila.Q41063878
Production of a DPP activity gradient in the early Drosophila embryo through the opposing actions of the SOG and TLD proteinsQ41080207
Human bone morphogenetic protein 2 contains a heparin-binding site which modifies its biological activityQ41211589
Fish are like flies are like frogs: conservation of dorsal-ventral patterning mechanisms.Q41459424
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectmorphogenesisQ815547
sequestering of BMP from receptor via BMP bindingQ21115972
sequestering of TGFbeta from receptor via TGFbeta bindingQ22303643
P1104number of pages14
P304page(s)3715-3728
P577publication date2009-11-01
P1433published inDevelopmentQ3025404
P1476titleThe extracellular regulation of bone morphogenetic protein signaling
P478volume136

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cites work (P2860)
Q40710612Accelerating protein release from microparticles for regenerative medicine applications
Q35676399Anterior segment alterations and comparative aqueous humor proteomics in the buphthalmic rabbit (an American Ophthalmological Society thesis).
Q27347557Anterograde Activin signaling regulates postsynaptic membrane potential and GluRIIA/B abundance at the Drosophila neuromuscular junction
Q48148998Anti-Müllerian hormone signaling is influenced by Follistatin 288, but not 14 other transforming growth factor beta superfamily regulators.
Q93153182Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin
Q37127457BMP Antagonist Gremlin 2 Limits Inflammation After Myocardial Infarction.
Q22065324BMP signaling components in embryonic transcriptomes of the hover fly Episyrphus balteatus (Syrphidae)
Q41591432BMP signaling in the development of the mouse esophagus and forestomach
Q37776859BMP signaling in vascular development and disease
Q38019707BMP signaling in wing development: A critical perspective on quantitative image analysis
Q51701151BMP2 Transfer to Neighboring Cells and Activation of Signaling.
Q33707750Binding between Crossveinless-2 and Chordin von Willebrand factor type C domains promotes BMP signaling by blocking Chordin activity
Q36268982Bmp2 conditional knockout in osteoblasts and endothelial cells does not impair bone formation after injury or mechanical loading in adult mice
Q38872877Bone Morphogenetic Proteins in Vascular Homeostasis and Disease
Q36035290Bone morphogenetic protein modulator BMPER is highly expressed in malignant tumors and controls invasive cell behavior
Q33804968CD44 and hyaluronan promote the bone morphogenetic protein 7 signaling response in murine chondrocytes
Q38812866CRIM1, a newfound cancer-related player, regulates the adhesion and migration of lung cancer cells
Q27347461Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling
Q37409544Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo
Q47071676Control of Dpp morphogen signalling by a secreted feedback regulator
Q35098166Crimpy inhibits the BMP homolog Gbb in motoneurons to enable proper growth control at the Drosophila neuromuscular junction
Q36010310Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium
Q35978899Crossveinless d is a vitellogenin-like lipoprotein that binds BMPs and HSPGs, and is required for normal BMP signaling in the Drosophila wing
Q92488443Crossveinless is a direct transcriptional target of Trachealess and Tango in Drosophila tracheal precursor cells
Q42377350Crossveinless-2 is required for the relocalization of Chordin protein within the vertebral field in mouse embryos
Q39774510Cv2, functioning as a pro-BMP factor via twisted gastrulation, is required for early development of nephron precursors
Q34626056Development of Physiologically Based Pharmacokinetic Model (PBPK) of BMP2 in Mice
Q36476190Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system.
Q90304779Disordered linkers in multidomain allosteric proteins: Entropic effect to favor the open state or enhanced local concentration to favor the closed state?
Q42131909Dorsal-ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases
Q42622861Dynamics of BMP signaling and distribution during zebrafish dorsal-ventral patterning
Q38538339EMBRYO DEVELOPMENT. BMP gradients: A paradigm for morphogen-mediated developmental patterning
Q34470346Efficient calculation of steady state probability distribution for stochastic biochemical reaction network
Q34341320Efficient reverse-engineering of a developmental gene regulatory network
Q34661949Expression and functional study of extracellular BMP antagonists during the morphogenesis of the digits and their associated connective tissues.
Q37066518Extracellular Regulation of Bone Morphogenetic Protein Activity by the Microfibril Component Fibrillin-1.
Q37932245Extracellular matrix in development: insights from mechanisms conserved between invertebrates and vertebrates
Q35561452Extracellular movement of signaling molecules.
Q37689990Extracellular regulation of BMP signaling
Q27026644Fine-tuned shuttles for bone morphogenetic proteins
Q41830263Free extracellular diffusion creates the Dpp morphogen gradient of the Drosophila wing disc
Q27005904Heparan sulfate in skeletal development, growth, and pathology: the case of hereditary multiple exostoses
Q89729149Homeobox D3, A Novel Link Between Bone Morphogenetic Protein 9 and Transforming Growth Factor Beta 1 Signaling
Q34429113ID family protein expression and regulation in hypoxic pulmonary hypertension
Q41636712Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells.
Q28547838In silico Mechano-Chemical Model of Bone Healing for the Regeneration of Critical Defects: The Effect of BMP-2
Q37397518Informatics approaches to understanding TGFbeta pathway regulation.
Q34365597Inhibition of bone morphogenetic proteins protects against atherosclerosis and vascular calcification
Q51412572Interplay between binding affinity and kinetics in protein-protein interactions.
Q39317513LRP1-dependent endocytic mechanism governs the signaling output of the bmp system in endothelial cells and in angiogenesis
Q26864974Making models match measurements: model optimization for morphogen patterning networks
Q37801803Mechanisms driving neural crest induction and migration in the zebrafish and Xenopus laevis
Q37358716Mechanisms of scaling in pattern formation
Q36752931Morphogen transport
Q36094301Multistep molecular mechanism for bone morphogenetic protein extracellular transport in the Drosophila embryo
Q88352257Nodal and BMP dispersal during early zebrafish development
Q34826199Notch and PKC are involved in formation of the lateral region of the dorso-ventral axis in Drosophila embryos
Q37047239Pentagone internalises glypicans to fine-tune multiple signalling pathways
Q37069124Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses
Q37889211Position matters: variability in the spatial pattern of BMP modulators generates functional diversity
Q22065789Primordial germ cells in mice
Q27311143Promotion of bone morphogenetic protein signaling by tetraspanins and glycosphingolipids
Q35873728Regulation of BMP activity and range in Drosophila wing development
Q42770522Regulation of TGFβ superfamily signaling by two separable domains of glypican LON-2 in C. elegans
Q47621324Regulation of glycosaminoglycan biogenesis is critical for sensitive-period-dependent vocal ontogeny.
Q38465654Regulators and effectors of bone morphogenetic protein signalling in the cardiovascular system.
Q38112402Repulsive guidance molecules (RGMs) and neogenin in bone morphogenetic protein (BMP) signaling
Q50229613Role of interleukin-10 in endochondral bone formation in mice: anabolic effect via the bone morphogenetic protein/Smad pathway
Q38890487SMOC can act as both an antagonist and an expander of BMP signaling.
Q42257664Secreted, receptor-associated bone morphogenetic protein regulators reduce stochastic noise intrinsic to many extracellular morphogen distributions
Q33755839Signaling pathways in cartilage repair
Q38019713Spatial regulation of BMP activity
Q35126888Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects.
Q27013995Systems control of BMP morphogen flow in vertebrate embryos
Q39107096TGF-β Family Signaling in Drosophila
Q21135289The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis
Q36126757The Gyc76C Receptor Guanylyl Cyclase and the Foraging cGMP-Dependent Kinase Regulate Extracellular Matrix Organization and BMP Signaling in the Developing Wing of Drosophila melanogaster
Q41268124The RGM protein DRAG-1 positively regulates a BMP-like signaling pathway in Caenorhabditis elegans
Q38116934The TGFbeta superfamily signaling pathway
Q91767495The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway
Q40733179The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development
Q57180801The extracellular protease AdamTS-B inhibits vein formation in the Drosophila wing
Q38056252The importance of geometry in mathematical models of developing systems
Q38071469The myotomal basement membrane: insight into laminin-111 function and its control by Sonic hedgehog signaling
Q37178004The neogenin/DCC homolog UNC-40 promotes BMP signaling via the RGM protein DRAG-1 in C. elegans
Q37919693The regulation of valvular and vascular sclerosis by osteogenic morphogens
Q33614316The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis.
Q36760208The role of mathematical models in understanding pattern formation in developmental biology
Q37962474Transforming growth factor-β in normal nociceptive processing and pathological pain models
Q47102060Two functional domains in C. elegans glypican LON-2 can independently inhibit BMP-like signaling
Q38853714Where do we stand on vascular calcification?
Q52736010You're going to need a bigger (glass bottom) boat.

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