| scholarly article | Q13442814 |
| P2093 | author name string | Michael L Cleary | |
| Everett H Chen | |||
| Paul M Ayton | |||
| P2860 | cites work | MLL2: A new mammalian member of the trx/MLL family of genes | Q22010267 |
| DNA methylation patterns and epigenetic memory | Q22065780 | ||
| Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias | Q24294368 | ||
| Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product | Q24310468 | ||
| Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax | Q24321584 | ||
| MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function | Q24540167 | ||
| The elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesis | Q24550876 | ||
| Mechanism of transcriptional regulation by methyl-CpG binding protein MBD1 | Q24553127 | ||
| Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells | Q24564511 | ||
| The solution structure of an HMG-I(Y)-DNA complex defines a new architectural minor groove binding motif | Q27741511 | ||
| MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines | Q28142772 | ||
| The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene | Q28201279 | ||
| Stage- and lineage-specific expression of the HOXA10 homeobox gene in normal and leukemic hematopoietic cells | Q28289099 | ||
| Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice | Q28509734 | ||
| MLL targets SET domain methyltransferase activity to Hox gene promoters | Q28609771 | ||
| ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation | Q29618299 | ||
| Altered Hox expression and segmental identity in Mll-mutant mice | Q29620391 | ||
| Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena | Q30304568 | ||
| Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL. | Q33887064 | ||
| The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX. | Q33995918 | ||
| Identification and characterization of the DNA binding domain of CpG-binding protein | Q34092615 | ||
| MLL3, a new human member of the TRX/MLL gene family, maps to 7q36, a chromosome region frequently deleted in myeloid leukaemia. | Q34118082 | ||
| MLL5, a homolog of Drosophila trithorax located within a segment of chromosome band 7q22 implicated in myeloid leukemia | Q34137337 | ||
| Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins | Q34405465 | ||
| Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia | Q34488469 | ||
| Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9 | Q35971222 | ||
| Nuclear punctate distribution of ALL-1 is conferred by distinct elements at the N terminus of the protein | Q36654659 | ||
| MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis | Q37478854 | ||
| The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation | Q38292124 | ||
| MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia | Q38294261 | ||
| Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias | Q40637557 | ||
| Transcriptional activation is a key function encoded by MLL fusion partners | Q40669934 | ||
| Common mechanism for oncogenic activation of MLL by forkhead family proteins | Q40695117 | ||
| The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10. | Q40734834 | ||
| Truncation of the Mll gene in exon 5 by gene targeting leads to early preimplantation lethality of homozygous embryos. | Q43728480 | ||
| A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias | Q44069634 | ||
| Isolation and characterization of a pufferfish MLL (mixed lineage leukemia)-like gene (fMll) reveals evolutionary conservation in vertebrate genes related to Drosophila trithorax | Q47775825 | ||
| Murine Polycomb- and trithorax-group genes regulate homeotic pathways and beyond. | Q52194910 | ||
| A carboxy-terminal domain of ELL is required and sufficient for immortalization of myeloid progenitors by MLL-ELL. | Q53403770 | ||
| Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling | Q61910882 | ||
| The leukemogenic fusion of MLL with ENL creates a novel transcriptional transactivator | Q73072154 | ||
| Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 : 11) abnormality | Q73787705 | ||
| Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny | Q77583284 | ||
| P433 | issue | 23 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 10470-10478 | |
| P577 | publication date | 2004-12-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein | |
| P478 | volume | 24 |
| Q64905283 | A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence. |
| Q24299122 | A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription |
| Q36082540 | Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus. |
| Q26829515 | Active DNA demethylation in post-mitotic neurons: a reason for optimism |
| Q44385509 | Alterations of the CxxC domain preclude oncogenic activation of mixed-lineage leukemia 2. |
| Q39405994 | Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia |
| Q24297763 | CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis |
| Q90854205 | Chromatin regulatory mechanisms and therapeutic opportunities in cancer |
| Q33802703 | Coordinated chromatin control: structural and functional linkage of DNA and histone methylation |
| Q47256933 | DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism |
| Q34894993 | Deep Sequencing the microRNA profile in rhabdomyosarcoma reveals down-regulation of miR-378 family members |
| Q34195379 | Developmentally induced Mll1 loss reveals defects in postnatal haematopoiesis |
| Q21135559 | Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1 |
| Q33769472 | Discovering cooperative relationships of chromatin modifications in human T cells based on a proposed closeness measure |
| Q35077007 | Discovery of MLL1 binding units, their localization to CpG Islands, and their potential function in mitotic chromatin |
| Q29616819 | Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome |
| Q33794291 | Downregulation of RUNX1/CBFβ by MLL fusion proteins enhances hematopoietic stem cell self-renewal |
| Q38435352 | Emerging therapeutic targets in human acute myeloid leukemia (part 2) - bromodomain inhibition should be considered as a possible strategy for various patient subsets |
| Q38852455 | Epigenetic balance of gene expression by Polycomb and COMPASS families |
| Q35901787 | Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis |
| Q30410234 | Functional specificity of CpG DNA-binding CXXC domains in mixed lineage leukemia. |
| Q53325167 | Grist for the MLL: how do MLL oncogenic fusion proteins generate leukemia stem cells? |
| Q30439092 | High resolution structure of the HDGF PWWP domain: a potential DNA binding domain. |
| Q36673042 | Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia |
| Q37405720 | Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia |
| Q34445102 | Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase |
| Q38310200 | Initiation of MLL-rearranged AML is dependent on C/EBPα |
| Q38163405 | Integrating DNA methylation dynamics into a framework for understanding epigenetic codes |
| Q33652604 | Introduction--Epiphanies in epigenetics. |
| Q29614517 | JmjC-domain-containing proteins and histone demethylation |
| Q37701261 | MLL fusion proteins link transcriptional coactivators to previously active CpG-rich promoters |
| Q30440771 | MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression. |
| Q37895709 | MLL-SEPTIN gene fusions in hematological malignancies |
| Q38190545 | Mechanisms of mixed-lineage leukemia |
| Q40130350 | Mechanisms of transcriptional regulation by MLL and its disruption in acute leukemia |
| Q38029260 | Menin as a hub controlling mixed lineage leukemia |
| Q37217351 | Menin critically links MLL proteins with LEDGF on cancer-associated target genes |
| Q33943731 | Mixed lineage leukemia: a structure-function perspective of the MLL1 protein |
| Q37710711 | Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing. |
| Q52369540 | Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin. |
| Q38161393 | Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis |
| Q37845655 | Molecular coupling of DNA methylation and histone methylation |
| Q38379210 | Molecular mechanisms of MLL-associated leukemia |
| Q36232545 | Molecular pathogenesis of MLL-associated leukemias |
| Q37620396 | Molecular pathology of mixed-lineage leukemia. |
| Q46947333 | Nonclinical pharmacokinetics and metabolism of EPZ-5676, a novel DOT1L histone methyltransferase inhibitor |
| Q50217919 | Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification. |
| Q34245737 | PAFc, a key player in MLL-rearranged leukemogenesis |
| Q95933711 | Pan-sarcoma genomic analysis of KMT2A rearrangements reveals distinct subtypes defined by YAP1-KMT2A-YAP1 and VIM-KMT2A fusions |
| Q27678800 | Potent inhibition of DOT1L as treatment of MLL-fusion leukemia |
| Q35041289 | Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways |
| Q28585873 | Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor |
| Q61448728 | RNA Polymerase II-Dependent Transcription Initiated by Selectivity Factor 1: A Central Mechanism Used by MLL Fusion Proteins in Leukemic Transformation |
| Q92482347 | Rewiring the Epigenetic Networks in MLL-Rearranged Leukemias: Epigenetic Dysregulation and Pharmacological Interventions |
| Q36138014 | Roles of a trithorax group gene, MLL, in hematopoiesis |
| Q52610467 | SIP1 participates in regulation of flowering time in rice by recruiting OsTrx1 to Ehd1. |
| Q33716402 | Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor. |
| Q40339478 | Silencing of the tumor suppressor gene FHIT is highly characteristic for MLL gene rearranged infant acute lymphoblastic leukemia |
| Q24304207 | Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase |
| Q58123482 | Somatic cell reprogrammed by oocyte: process and barricade |
| Q27658663 | Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia. |
| Q41352951 | TBP loading by AF4 through SL1 is the major rate-limiting step in MLL fusion-dependent transcription |
| Q38060521 | Targeting genetic alterations in protein methyltransferases for personalized cancer therapeutics |
| Q88561872 | The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia |
| Q24319075 | The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis |
| Q37001995 | The PHD fingers of MLL block MLL fusion protein-mediated transformation |
| Q34566036 | The chromatin signaling pathway: diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes |
| Q36465820 | The dynamics of DNA methylation in schizophrenia and related psychiatric disorders. |
| Q37874929 | The heterogeneity of pediatric MLL-rearranged acute myeloid leukemia |
| Q37522825 | The molecular biology of mixed lineage leukemia |
| Q37730254 | The molecular signature of oncofusion proteins in acute myeloid leukemia. |
| Q42091115 | The role of menin in hematopoiesis |
| Q27667275 | The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain |
| Q37234595 | Therapeutic targeting of MLL. |
| Q37949245 | Transcriptional regulation of macrophage polarization: enabling diversity with identity |
| Q35018755 | Two decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia. |
| Q36239212 | When epigenetics kills: MLL fusion proteins in leukemia |
| Q92099533 | Why are so many MLL lysine methyltransferases required for normal mammalian development? |
| Q64954432 | Wiedemann-Steiner syndrome with a novel pathogenic variant in KMT2A: a case report. |
| Q36936680 | ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection |
| Q37504409 | p27kip1 maintains a subset of leukemia stem cells in the quiescent state in murine MLL-leukemia |
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