The shape of motile cells

scientific article published on September 2009

The shape of motile cells is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.CUB.2009.06.053
P932PMC publication ID2864320
P698PubMed publication ID19906578
P5875ResearchGate publication ID38083104

P50authorAlex MogilnerQ18350998
P2093author name stringKinneret Keren
P2860cites workRegulation of cell movement is mediated by stretch-activated calcium channelsQ59054521
Principles of locomotion for simple-shaped cellsQ59067962
Persistent, directional motility of cells and cytoplasmic fragments in the absence of microtubulesQ59079016
Contact dynamics during keratocyte motilityQ63407310
Fibroblast contractility and actin organization are stimulated by microtubule inhibitorsQ69127112
Dynamics of fibroblast spreadingQ71921687
Analysis of actin dynamics at the leading edge of crawling cells: implications for the shape of keratocyte lamellipodiaQ73373431
How do microtubules guide migrating cells?Q78599812
Myosin-X is a molecular motor that functions in filopodia formationQ24299253
Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodiaQ24310847
The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filamentsQ24653380
Comparative dynamics of retrograde actin flow and focal adhesions: formation of nascent adhesions triggers transition from fast to slow flowQ27300187
Synthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migrationQ27300702
Emergence of large-scale cell morphology and movement from local actin filament growth dynamicsQ27334367
An actin-based wave generator organizes cell motilityQ27334396
Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreadingQ27438144
Ordered patterns of cell shape and orientational correlation during spontaneous cell migrationQ27438146
Cell migration: integrating signals from front to backQ27860670
Cellular motility driven by assembly and disassembly of actin filamentsQ27860676
Invadopodia: specialized cell structures for cancer invasionQ28251084
A role for cytoplasmic dynein and LIS1 in directed cell movementQ28591271
Cell shape provides global control of focal adhesion assemblyQ29041392
Rho GTPases control polarity, protrusion, and adhesion during cell movementQ29614244
Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysisQ29615074
Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysisQ29615193
Conserved microtubule-actin interactions in cell movement and morphogenesisQ29615212
Geometric control of cell life and deathQ29615213
Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substratesQ29616030
Mechanism of filopodia initiation by reorganization of a dendritic networkQ29616648
Two distinct actin networks drive the protrusion of migrating cellsQ29617078
Integrins in cell migration--the actin connectionQ30437361
Self-organization of actin filament orientation in the dendritic-nucleation/array-treadmilling modelQ30479338
Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcementQ30480404
Actin-myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motilityQ30480556
Exploring the control circuit of cell migration by mathematical modelingQ30481649
GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoA.Q30481848
Performance of a population of independent filaments in lamellipodial protrusionQ30482773
Dependence of invadopodia function on collagen fiber spacing and cross-linking: computational modeling and experimental evidenceQ30483094
Myosin II activity facilitates microtubule bundling in the neuronal growth cone neckQ30483711
Coordination of actin filament and microtubule dynamics during neurite outgrowthQ30484871
Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networksQ30489597
Talin depletion reveals independence of initial cell spreading from integrin activation and tractionQ30490335
Cell migration as a five-step cycle.Q30697427
The actin-based nanomachine at the leading edge of migrating cellsQ30761122
Lamellipodial actin mechanically links myosin activity with adhesion-site formationQ30834196
The influence of cell mechanics, cell-cell interactions, and proliferation on epithelial packingQ33310528
Arp2/3 branched actin network mediates filopodia-like bundles formation in vitro.Q33372331
Actin machinery: pushing the envelope.Q33840347
Mechanism of shape determination in motile cellsQ33882327
Self-organization of a propulsive actin network as an evolutionary processQ33944495
Pattern formation by local self-activation and lateral inhibitionQ33986085
Regulation of actin dynamics in rapidly moving cells: a quantitative analysisQ34178584
Eukaryotic chemotaxis: distinctions between directional sensing and polarizationQ34188022
Morphology of the lamellipodium and organization of actin filaments at the leading edge of crawling cellsQ34351900
Dynamics of membranes driven by actin polymerizationQ34352973
Self-polarization and directional motility of cytoplasmQ34487647
Adaptation of core mechanisms to generate cell polarityQ35109711
Pearling in cells: a clue to understanding cell shapeQ35617177
Crawling toward a unified model of cell mobility: spatial and temporal regulation of actin dynamics.Q35799956
Cytoskeletal mechanisms responsible for invasive migration of neoplastic cellsQ35878892
Foot and mouth: podosomes, invadopodia and circular dorsal rufflesQ35887297
Spatio-temporal analysis of eukaryotic cell motility by improved force cytometryQ35925606
Model of polarization and bistability of cell fragmentsQ36156503
Mechanics of crawling cellsQ36166800
Mechanism and role of localized activation of Rho-family GTPases in growth factor-stimulated fibroblasts and neuronal cells.Q36206370
Cell migration in tumorsQ36228553
The comings and goings of actin: coupling protrusion and retraction in cell motilityQ36228793
Cell migration in 3D matrixQ36236442
Multinucleation-induced improvement of the spreading of transformed cells on the substratum.Q36261156
Analysis of the actin-myosin II system in fish epidermal keratocytes: mechanism of cell body translocationQ36273905
Cell shape and cell divisionQ36625784
The stochastic dynamics of filopodial growthQ36632087
Asymmetric focal adhesion disassembly in motile cells.Q37033437
One-dimensional topography underlies three-dimensional fibrillar cell migrationQ37124347
Implications of a poroelastic cytoplasm for the dynamics of animal cell shapeQ37131643
Visualizing and quantifying adhesive signalsQ37202389
On the shape of migrating cells--a 'front-to-back' modelQ37236783
Controlling cell lengthQ37244842
The mechanical integrin cycle.Q37360851
Proteolytic interstitial cell migration: a five-step process.Q37372558
The relationship of fibroblast translocations to cell morphology and stress fibre density.Q38537063
Subcellular curvature at the perimeter of micropatterned cells influences lamellipodial distribution and cell polarity.Q39954251
Filamentous network mechanics and active contractility determine cell and tissue shapeQ39965431
Decreased polarity and increased random motility in PtK1 epithelial cells correlate with inhibition of endosomal recyclingQ40239771
Arp2/3 complex-mediated actin polymerisation occurs on specific pre-existing networks in cells and requires spatial restriction to sustain functional lamellipod extensionQ40291374
Cell distribution of stress fibres in response to the geometry of the adhesive environmentQ40301712
The three-dimensional dynamics of actin waves, a model of cytoskeletal self-organization.Q41832167
Cell spreading and lamellipodial extension rate is regulated by membrane tensionQ41931161
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule levelQ41978648
Geometric determinants of directional cell motility revealed using microcontact printingQ42833133
Cell behaviour on micropatterned substrata: limits of extracellular matrix geometry for spreading and adhesionQ42833375
Regulation of mechanical interactions between fibroblasts and the substratum by stretch-activated Ca2+ entryQ42833886
Propagation of mechanical stress through the actin cytoskeleton toward focal adhesions: model and experimentQ42972011
Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophilsQ44530451
Potential for control of signaling pathways via cell size and shapeQ47323029
Rho GTPasesQ47724821
Relationships between actin regulatory mechanisms and measurable state variables.Q51040333
Contractility and retrograde flow in lamellipodium motion.Q51938141
Polarization and movement of keratocytes: a multiscale modelling approach.Q51939254
Endothelial cell protrusion and migration in three-dimensional collagen matrices.Q53641844
The locomotion of fibroblasts in culture I. Movements of the leading edgeQ53755605
The composition and dynamics of cell-substratum adhesions in locomoting fish keratocytes.Q55067331
Limits of filopodium stability.Q55514892
Cooperativity between Cell Contractility and AdhesionQ57581639
P433issue17
P407language of work or nameEnglishQ1860
P304page(s)R762-71
P577publication date2009-09-01
P1433published inCurrent BiologyQ1144851
P1476titleThe shape of motile cells
P478volume19

Reverse relations

cites work (P2860)
Q36528371A chemically-defined screening platform reveals behavioral similarities between primary human mesenchymal stem cells and endothelial cells.
Q30576118A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells
Q27001708A growing family: the expanding universe of the bacterial cytoskeleton
Q27315159A lateral signalling pathway coordinates shape volatility during cell migration
Q37987096A review of models of fluctuating protrusion and retraction patterns at the leading edge of motile cells
Q30539600A role for actin arcs in the leading-edge advance of migrating cells
Q41876426A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes
Q35827505A secreted MMP is required for reepithelialization during wound healing
Q41900901A simple force-motion relation for migrating cells revealed by multipole analysis of traction stress
Q39066584Active contractions in single suspended epithelial cells.
Q27313955Advancing Edge Speeds of Epithelial Monolayers Depend on Their Initial Confining Geometry
Q27321445An adhesion-dependent switch between mechanisms that determine motile cell shape
Q27312428An intact centrosome is required for the maintenance of polarization during directional cell migration
Q39179468Analysis of multiple physical parameters for mechanical phenotyping of living cells
Q30547708Analysis of the local organization and dynamics of cellular actin networks
Q51109919Analytical solutions of actin-retrograde-flow in a circular stationary cell: a mechanical point of view.
Q28483947Arhgef15 promotes retinal angiogenesis by mediating VEGF-induced Cdc42 activation and potentiating RhoJ inactivation in endothelial cells
Q39113265Atomic force microscopy imaging of live mammalian cells
Q57286198Atomic force microscopy reveals new biophysical markers for monitoring subcellular changes in oxidative injury: Neuroprotective effects of quercetin at the nanoscale
Q37345613Boundaries steer the contraction of active gels
Q35497542Boyden chamber-based method for characterizing the distribution of adhesions and cytoskeletal structure in HT1080 fibrosarcoma cells
Q39627627Calmodulin-kinases regulate basal and estrogen stimulated medulloblastoma migration via Rac1.
Q37915388Cell motility: the integrating role of the plasma membrane.
Q44575020Closing the loop: lamellipodia dynamics from the perspective of front propagation
Q40998713Collective motion of cells crawling on a substrate: roles of cell shape and contact inhibition
Q53369051Comparative Assessment of Oral Mesenchymal Stem Cells Isolated from Healthy and Diseased Tissues.
Q52552970Complex self-propelled rings: a minimal model for cell motility.
Q47294328Computational modeling of single-cell mechanics and cytoskeletal mechanobiology.
Q90795283Condensed desmin and actin cytoskeletal communication in lipid droplets
Q33563348Contact guidance requires spatial control of leading-edge protrusion.
Q46084373Continuum modeling and numerical simulation of cell motility
Q27318856Crawling and Gliding: A Computational Model for Shape-Driven Cell Migration
Q30528218Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain
Q30570343Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity.
Q36468648Current concepts of the podocyte in nephrotic syndrome
Q37778594Cytoskeletal Cross-linking and Bundling in Motor-Independent Contraction
Q42773442Decoding information in cell shape
Q27300787Disentangling Membrane Dynamics and Cell Migration; Differential Influences of F-actin and Cell-Matrix Adhesions
Q37867601Dynamic lineage analysis of embryonic morphogenesis using transgenic quail and 4D multispectral imaging
Q91739157Dynamic spherical harmonics approach for shape classification of migrating cells
Q27316501Dynamics of Cell Ensembles on Adhesive Micropatterns: Bridging the Gap between Single Cell Spreading and Collective Cell Migration
Q42090243Effects of 3D geometries on cellular gradient sensing and polarization
Q27318582Effects of adhesion dynamics and substrate compliance on the shape and motility of crawling cells
Q28238533Emergent complexity of the cytoskeleton: from single filaments to tissue
Q40052473Epithelial-mesenchymal transition transcription factors control pluripotent adult stem cell migration in vivo in planarians.
Q47813317Excitable Signal Transduction Networks in Directed Cell Migration.
Q35866829Excitable actin dynamics in lamellipodial protrusion and retraction
Q40533195Existence of and decay to equilibrium of the filament end density along the leading edge of the lamellipodium.
Q30539211Extracellular matrix proteins and displacement of cultured fibroblasts from duodenal biopsies in celiac patients and controls
Q35201641Growth on poly(L-lactic acid) porous scaffold preserves CD73 and CD90 immunophenotype markers of rat bone marrow mesenchymal stromal cells
Q27004734Heading off with the herd: how cancer cells might maneuver supernumerary centrosomes for directional migration
Q35217492High-speed force mapping on living cells with a small cantilever atomic force microscope.
Q90220716Hydroxyapatite mineral enhances malignant potential in a tissue-engineered model of ductal carcinoma in situ (DCIS)
Q27345333In vivo imaging reveals a pioneer wave of monocyte recruitment into mouse skin wounds
Q27342988Investigating biomechanical noise in neuroblastoma cells using the quartz crystal microbalance
Q27302286Lipopolysaccharide O-antigen prevents phagocytosis of Vibrio anguillarum by rainbow trout (Oncorhynchus mykiss) skin epithelial cells
Q57255908Mapping the mechanical stiffness of live cells with the scanning ion conductance microscope
Q93012660Mechanical stress alters protein O-GlcNAc in human periodontal ligament cells
Q33858720Mechanisms controlling cell size and shape during isotropic cell spreading
Q47262581Mechanoreciprocity in cell migration.
Q35746819Medicinal Plants: A Potential Source of Compounds for Targeting Cell Division.
Q39126929Model of turnover kinetics in the lamellipodium: implications of slow- and fast- diffusing capping protein and Arp2/3 complex
Q52878261Modeling crawling cell movement on soft engineered substrates.
Q38190238Multiscale modeling of cell shape from the actin cytoskeleton
Q30009514Myosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation
Q30385390Myosin II Activity Softens Cells in Suspension.
Q28564307Myosin IIb regulates actin dynamics during synaptic plasticity and memory formation
Q52381977Persistent random deformation model of cells crawling on a gel surface.
Q30538190Phase geometries of two-dimensional excitable waves govern self-organized morphodynamics of amoeboid cells.
Q28581438Phospho-NHE3 forms membrane patches and interacts with beta-actin to sense and maintain constant direction during cell migration
Q35895070Physical model for self-organization of actin cytoskeleton and adhesion complexes at the cell front
Q30656470Physical principles of membrane remodelling during cell mechanoadaptation
Q27317392Plasticity in the macromolecular-scale causal networks of cell migration
Q93099566Predicting the future direction of cell movement with convolutional neural networks
Q91861078Quasi-periodic migration of single cells on short microlanes
Q35534799Reconstitution of amoeboid motility in vitro identifies a motor-independent mechanism for cell body retraction
Q35132831Redundant mechanisms for stable cell locomotion revealed by minimal models
Q37682275RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo
Q50895731Runx3 inhibits melanoma cell migration through regulation of cell shape change.
Q47708196Sequential inactivation of Rho GTPases and Lim kinase by Pseudomonas aeruginosa toxins ExoS and ExoT leads to endothelial monolayer breakdown
Q64981806Shape and Size Control of Artificial Cells for Bottom-Up Biology.
Q28508939Silencing of OSBP-related protein 8 (ORP8) modifies the macrophage transcriptome, nucleoporin p62 distribution, and migration capacity
Q36319424Single Cell Transcriptomics, Mega-Phylogeny, and the Genetic Basis of Morphological Innovations in Rhizaria
Q38461742Spatiotemporal coordinated hierarchical properties of cellular protrusion revealed by multiscale analysis
Q38811650Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells
Q47671850Swinging motion of active deformable particles in Poiseuille flow.
Q30499358The COPI vesicle complex binds and moves with survival motor neuron within axons
Q35899018The Role of Stress Fibers in the Shape Determination Mechanism of Fish Keratocytes
Q39094458The assembly and function of perinuclear actin cap in migrating cells
Q53557742The c-Rel subunit of NF-κB is a crucial regulator of phenotype and motility of HaCaT keratinocytes.
Q92001031The excitable signal transduction networks: movers and shapers of eukaryotic cell migration
Q37949258The podocyte cytoskeleton--key to a functioning glomerulus in health and disease
Q30536181The role of microtubules in neutrophil polarity and migration in live zebrafish.
Q91985657The role of nonmuscle myosin 2A and 2B in the regulation of mesenchymal cell contact guidance
Q50956857The shift in GH3 cell shape and cell motility is dependent on MLCK and ROCK.
Q37785158Theoretical Concepts and Models of Cellular Mechanosensing
Q41900867Theoretical analysis of membrane tension in moving cells
Q50749342Theoretical model for cell migration with gradient sensing and shape deformation.
Q27333926Theoretical model for cellular shapes driven by protrusive and adhesive forces
Q39188045Time-dependent traction force microscopy for cancer cells as a measure of invasiveness.
Q39634040Transducer of Cdc42-dependent actin assembly promotes epidermal growth factor-induced cell motility and invasiveness
Q38044077Traveling waves in actin dynamics and cell motility
Q50269152Ultrastructural analysis of human bone marrow mesenchymal stem cells during in vitro osteogenesis and chondrogenesis
Q30499685Vimentin organization modulates the formation of lamellipodia
Q37941707Viral infection: Moving through complex and dynamic cell-membrane structures.

Search more.