A +220 GATA motif mediates basal but not endotoxin-repressible expression of the von Willebrand factor promoter in Hprt-targeted transgenic mice

scientific article published on 30 May 2009

A +220 GATA motif mediates basal but not endotoxin-repressible expression of the von Willebrand factor promoter in Hprt-targeted transgenic mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1538-7836.2009.03501.X
P932PMC publication ID5303625
P698PubMed publication ID19496923
P5875ResearchGate publication ID26267167

P2093author name stringJ Liu
Y Okada
K Yano
T Minami
W C Aird
S-C Shih
Y Kanki
E Jin
P2860cites workCharacterisation of the tumour necrosis factor (TNF)-(alpha) response elements in the human ICAM-2 promoterQ28138699
Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesisQ28284677
von Willebrand factor: two sides of a coinQ33367858
The NFY transcription factor inhibits von Willebrand factor promoter activation in non-endothelial cells through recruitment of histone deacetylasesQ34168378
Human von Willebrand factor gene sequences target expression to a subpopulation of endothelial cells in transgenic miceQ34345405
The role of von Willebrand factor in thrombus formationQ34627119
A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endotheliumQ34627363
Endothelial cell heterogeneityQ35101946
Endothelial cell gene regulationQ36258331
Vascular bed-specific expression of an endothelial cell gene is programmed by the tissue microenvironmentQ36263590
Endothelial-cell-specific regulation of von Willebrand factor gene expressionQ36645432
A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo.Q36868732
Single-copy transgenic mice with chosen-site integrationQ37384432
PDGF mediates cardiac microvascular communicationQ37384601
Combined genomic and antisense analysis reveals that the transcription factor Erg is implicated in endothelial cell differentiationQ38294523
Function of GATA transcription factors in induction of endothelial vascular cell adhesion molecule-1 by tumor necrosis factor-alphaQ38300097
An NF1-like protein functions as a repressor of the von Willebrand factor promoterQ38353753
Cell type-specific regulation of von Willebrand factor expression by the E4BP4 transcriptional repressorQ40501206
Thrombin stimulation of the vascular cell adhesion molecule-1 promoter in endothelial cells is mediated by tandem nuclear factor-kappa B and GATA motifsQ40776396
Transforming growth factor-beta 1-mediated inhibition of the flk-1/KDR gene is mediated by a 5'-untranslated region palindromic GATA siteQ40839613
Targeting the Hprt locus in mice reveals differential regulation of Tie2 gene expression in the endotheliumQ40851626
Ets transcription factors bind and transactivate the core promoter of the von Willebrand factor gene.Q41069495
Differential regulation of the von Willebrand factor and Flt-1 promoters in the endothelium of hypoxanthine phosphoribosyltransferase-targeted miceQ44189782
Thrombin stimulation of vascular adhesion molecule-1 in endothelial cells is mediated by protein kinase C (PKC)-delta-NF-kappa B and PKC-zeta-GATA signaling pathwaysQ44257234
Ets motifs are necessary for endothelial cell-specific expression of a 723-bp Tie-2 promoter/enhancer in Hprt targeted transgenic miceQ44534231
Oct-1 is involved in the transcriptional repression of the von willebrand factor gene promoter.Q47725290
Tissue distribution and regulation of murine von Willebrand factor gene expression in vivo.Q48379950
Targeting of human eNOS promoter to the Hprt locus of mice leads to tissue-restricted transgene expressionQ57897021
Characterization of the mouse von Willebrand factor promoterQ57897025
A single nucleotide polymorphism at nucleotide -1793 in the von Willebrand factor (VWF) regulatory region is associated with plasma VWF:Ag levelsQ73883397
Tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta down-regulate intercellular adhesion molecule (ICAM)-2 expression on the endotheliumQ77386394
The NFY transcription factor functions as a repressor and activator of the von Willebrand factor promoterQ77768061
Variation at the von Willebrand factor (vWF) gene locus is associated with plasma vWF:Ag levels: identification of three novel single nucleotide polymorphisms in the vWF gene promoterQ77850433
Sequences in intron 51 of the von Willebrand factor gene target promoter activation to a subset of lung endothelial cells in transgenic miceQ80119142
P433issue8
P921main subjectendotoxinsQ319997
P304page(s)1384-1392
P577publication date2009-05-30
P1433published inJournal of Thrombosis and HaemostasisQ6296004
P1476titleA +220 GATA motif mediates basal but not endotoxin-repressible expression of the von Willebrand factor promoter in Hprt-targeted transgenic mice
P478volume7

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cites work (P2860)
Q64066089Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner
Q42768111Constitutively active Notch1 signaling promotes endothelial‑mesenchymal transition in a conditional transgenic mouse model
Q34027281Epigenetically coordinated GATA2 binding is necessary for endothelium-specific endomucin expression
Q34310576Functional characterization of a 13-bp deletion (c.-1522_-1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease.
Q47160378GATA3-induced vWF upregulation in the lung adenocarcinoma vasculature
Q88984493Inflammation, von Willebrand factor, and ADAMTS13
Q92404876Plasma levels of von Willebrand factor in type 2 diabetes patients with and without cardiovascular diseases: A meta-analysis
Q34045555Plasma von Willebrand factor level is transiently elevated in a rat model of acute myocardial infarction
Q33429209Regulation of VWF expression, and secretion in health and disease
Q36873319Role of RNA splicing in mediating lineage-specific expression of the von Willebrand factor gene in the endothelium
Q34568916Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle.
Q33754660Vascular endothelial growth factor activation of endothelial cells is mediated by early growth response-3.

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