Development and use of the lens epithelial explant system to study lens differentiation and cataractogenesis

scientific article published on 17 December 2009

Development and use of the lens epithelial explant system to study lens differentiation and cataractogenesis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.PRETEYERES.2009.12.001
P932PMC publication ID2964862
P698PubMed publication ID20006728
P5875ResearchGate publication ID40684506

P50authorJudith A West-MaysQ88373662
P2093author name stringFrank J Lovicu
Guiseppe Pino
P2860cites workFibroblast growth factor receptor signaling is essential for lens fiber cell differentiationQ28507340
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Thapsigargin-coated intraocular lenses inhibit human lens cell growth.Q34438418
Lentropin, a protein that controls lens fiber formation, is related functionally and immunologically to the insulin-like growth factorsQ34613480
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Synthesis of interleukin-1 and prostaglandin E2 by lens epithelial cells of human cataractsQ37297661
Differentiation of rat lens epithelial cells in tissue culture. (I) Effects of cell density, medium and embryonic age of initial cultureQ39407841
Tissue culture of lens epithelial cells from normal and Nakano miceQ39807650
Induction of the eye lensQ40296870
Biochemical and immunological studies of lentoid formation in cultures of embryonic chick neural retina and day-old chick lens epitheliumQ40828392
Cell division, cell elongation and the co-ordination of crystallin gene expression during lens morphogenesis in the ratQ40912112
The age of rats affects the response of lens epithelial explants to fibroblast growth factor. An ultrastructural analysisQ41123835
A lens fibre differentiation factor from calf neural retinaQ41493301
Myofibroblast-like cells in human anterior capsular cataractQ41573202
Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor.Q41675605
Development, advantages, and methods of the continuous circular capsulorhexis techniqueQ41861383
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A light and electron microscopic study of anterior subcapsular cataractsQ44582342
Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic miceQ47731206
Effect of cataract surgery on aqueous TGF-beta and lens epithelial cell proliferationQ47860521
Characterization of avian frizzled genes in cranial placode developmentQ47865505
Evidence that fibroblast growth factor promotes lens fibre differentiationQ48210454
Differential expression of fibroblast growth factor receptors during rat lens morphogenesis and growth.Q52193202
Generation of transparency and cellular organization in lens explants.Q53491890
Ubiquitin-proteasome pathway function is required for lens cell proliferation and differentiation.Q53621180
Lens epithelial cell migration onto the posterior capsule in vitro.Q53993175
Cell division, cell elongation and distribution of alpha-, beta- and gamma-crystallins in the rat lensQ67328927
The pathology of after-cataract. A minireviewQ67866028
Age-related changes in fibre differentiation of rat lens epithelial cells in vitroQ68288112
Induction of lens fibre differentiation by acidic and basic fibroblast growth factor (FGF)Q69447120
Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentrationQ69459592
Structural analysis of lens epithelial explants induced to differentiate into fibres by fibroblast growth factor (FGF)Q69749489
Neural retinas promote cell division and fibre differentiation in lens epithelial explantsQ70361636
Onset of fibre differentiation in cultured rat lens epithelium under the influence of neural retina-conditioned mediumQ70381191
[Growth factors and cell cultures: a new approach for research in ophthalmology]Q70535251
The expression of differentiation by chicken lens epithelium in in vitro cell cultureQ70684781
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Spatio-temporal distribution of acidic and basic FGF indicates a role for FGF in rat lens morphogenesisQ71614984
Extracellular FGF-1 acts as a lens differentiation factor in transgenic miceQ71695334
Effect of serum on the synthesis of RNA and of DNA in the cultured lens epithelium of the chick embryo: initiation of lens fiber formation in vitroQ71840463
Cataract induction in lenses cultured with transforming growth factor-betaQ71846993
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A ring to support the capsular bag after continuous curvilinear capsulorhexisQ72731040
Human lens epithelial cell proliferation in a protein-free mediumQ73089206
Expression of FGF-1 and FGF-2 mRNA during lens morphogenesis, differentiation and growthQ73193496
TGF-beta2-induced matrix modification and cell transdifferentiation in the human lens capsular bagQ74389414
LENS DEVELOPMENT: FIBER ELONGATION AND LENS ORIENTATIONQ76598233
FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signallingQ77363736
LENS DEVELOPMENT. II. THE DIFFERENTIATION OF EMBRYONIC CHICK LENS EPITHELIAL CELLS IN VITRO AND IN VIVOQ78495667
Duration of ERK1/2 phosphorylation induced by FGF or ocular media determines lens cell fateQ80025078
The role of Hsp70 and Hsp90 in TGF-beta-induced epithelial-to-mesenchymal transition in rat lens epithelial explantsQ80217901
FGF-2 counteracts loss of TGFbeta affected cells from rat lens explants: implications for PCO (after cataract)Q80433329
Aqueous humour- and growth factor-induced lens cell proliferation is dependent on MAPK/ERK1/2 and Akt/PI3-K signallingQ83309346
P433issue2
P304page(s)135-143
P577publication date2009-12-17
P1433published inProgress in Retinal and Eye ResearchQ15760062
P1476titleDevelopment and use of the lens epithelial explant system to study lens differentiation and cataractogenesis
P478volume29

Reverse relations

cites work (P2860)
Q42054514A balance of FGF and BMP signals regulates cell cycle exit and Equarin expression in lens cells
Q37629555Bone Morphogenetic Protein-7 Suppresses TGFβ2-Induced Epithelial-Mesenchymal Transition in the Lens: Implications for Cataract Prevention
Q30352305Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract.
Q28571470Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation
Q98782026Lens fiber cell differentiation occurs independently of fibroblast growth factor receptor signaling in the absence of Pten
Q36846663Nuclear translocation of myocardin-related transcription factor-A during transforming growth factor beta-induced epithelial to mesenchymal transition of lens epithelial cells
Q57802761Proteome-transcriptome analysis and proteome remodeling in mouse lens epithelium and fibers
Q36594675Regulation of c-Maf and αA-Crystallin in Ocular Lens by Fibroblast Growth Factor Signaling
Q37852901The lens as a model for fibrotic disease
Q48250999Ultraviolet B Radiation Stimulates the Interaction between Nuclear Factor of Activated T Cells 5 (NFAT5) and Nuclear Factor-Kappa B (NF-κB) in Human Lens Epithelial Cells
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Q90249957Wnt Signaling in vascular eye diseases
Q39300342Wnt3a promotes epithelial-mesenchymal transition, migration, and proliferation of lens epithelial cells.
Q37384362β-Catenin/CBP-Dependent Signaling Regulates TGF-β-Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells

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