EUK-134 ameliorates nNOSμ translocation and skeletal muscle fiber atrophy during short-term mechanical unloading

scientific article published on 29 January 2014

EUK-134 ameliorates nNOSμ translocation and skeletal muscle fiber atrophy during short-term mechanical unloading is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPREGU.00371.2013
P932PMC publication ID3962621
P698PubMed publication ID24477538
P5875ResearchGate publication ID259985532

P50authorJeffrey M HordQ85064486
P2093author name stringYang Lee
John M Lawler
Daniel A Martinez
Kumar Joshi
Angelo Ramirez
Mary Kunst
Rachel E Botchlett
P2860cites workTransgenic mice expressing mutant caveolin-3 show severe myopathy associated with increased nNOS activityQ28510735
Antioxidant administration attenuates mechanical ventilation-induced rat diaphragm muscle atrophy independent of protein kinase B (PKB Akt) signallingQ28572937
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophyQ29619282
Microtubules underlie dysfunction in duchenne muscular dystrophy.Q30557507
Functional deficits in nNOSmu-deficient skeletal muscle: myopathy in nNOS knockout miceQ33375717
Ros-mediated activation of NF-kappaB and Foxo during muscle disuseQ33551292
Skeletal muscle NADPH oxidase is increased and triggers stretch-induced damage in the mdx mouseQ33781098
Effect of aging on cellular mechanotransductionQ33925573
Oxidation enhances myofibrillar protein degradation via calpain and caspase-3.Q34091517
Canonical TRP channels and mechanotransduction: from physiology to disease states.Q34116745
Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathwaysQ34421809
Adaptations in skeletal muscle disuse or decreased-use atrophyQ34985398
Mitochondrial-targeted antioxidants protect skeletal muscle against immobilization-induced muscle atrophyQ35562060
Adaptation of mouse skeletal muscle to long-term microgravity in the MDS missionQ35858592
NO production results in suspension-induced muscle atrophy through dislocation of neuronal NOS.Q35951455
Mitochondria-targeted antioxidants protect against mechanical ventilation-induced diaphragm weaknessQ37197868
Compartmentalization of redox signaling through NADPH oxidase-derived ROS.Q37322476
Redox signaling across cell membranesQ37342994
Calcium and the damage pathways in muscular dystrophyQ37710975
Activation of calcium signaling through Trpv1 by nNOS and peroxynitrite as a key trigger of skeletal muscle hypertrophyQ39234400
Nitric oxide regulates stretch-induced proliferation in C2C12 myoblastsQ39666443
Orally available Mn porphyrins with superoxide dismutase and catalase activitiesQ39841516
Sarcolemmal neuronal nitric oxide synthase defect in limb-girdle muscular dystrophy: an adverse modulating factor in the disease course?Q39994932
Chronic Exercise Training Down-Regulates TNF-α and Atrogin-1/MAFbx in Mouse Gastrocnemius Muscle Atrophy Induced by Hindlimb UnloadingQ42002402
Oxidation of nitric oxide by oxomanganese-salen complexes: a new mechanism for cellular protection by superoxide dismutase/catalase mimeticsQ43002076
Is oxidative stress a cause or consequence of disuse muscle atrophy in mice? A proteomic approach in hindlimb-unloaded miceQ43263806
Involvement of nitric oxide synthase in skeletal muscle adaptation to chronic overloadQ43964435
Aerobic capacities in the skeletal muscles of Weddell seals: key to longer dive durations?Q44200312
Hindlimb unloading increases oxidative stress and disrupts antioxidant capacity in skeletal muscleQ44491177
Expression of a NOS transgene in dystrophin-deficient muscle reduces muscle membrane damage without increasing the expression of membrane-associated cytoskeletal proteinsQ44807148
Oxidative stress induces lipid-raft-mediated activation of Src homology 2 domain-containing protein-tyrosine phosphatase 2 in astrocytesQ46059823
Redox regulation of diaphragm proteolysis during mechanical ventilationQ46717248
Differential response of heat shock proteins to hindlimb unloading and reloading in the soleusQ46782563
Increased antioxidant capacity does not attenuate muscle atrophy caused by unweightingQ46963101
Composition and size of type I, IIA, IID/X, and IIB fibers and citrate synthase activity of rat muscleQ47340104
Mechanical ventilation-induced oxidative stress in the diaphragm.Q51296490
Mechanical ventilation-induced diaphragmatic atrophy is associated with oxidative injury and increased proteolytic activity.Q51698128
Biphasic stress response in the soleus during reloading after hind limb unloading.Q53214037
Alterations in skeletal perfusion with simulated microgravity: a possible mechanism for bone remodeling.Q54039500
The role of reactive oxygen species in the hearts of dystrophin-deficient mdx miceQ57374679
Fibre-related nitric oxide synthase (NOS) in Duchenne muscular dystrophyQ58001788
Supplementation of vitamin E may attenuate skeletal muscle immobilization atrophyQ58230327
Superoxide dismutase mimetic with catalase activity, EUK-134, attenuates the multiple organ injury and dysfunction caused by endotoxin in the ratQ77505743
Bowman-Birk inhibitor concentrate prevents atrophy, weakness, and oxidative stress in soleus muscle of hindlimb-unloaded miceQ79365664
Hsp70 overexpression inhibits NF-kappaB and Foxo3a transcriptional activities and prevents skeletal muscle atrophyQ81679902
Effect of flywheel-based resistance exercise on processes contributing to muscle atrophy during unloading in adult ratsQ83118353
Amplification of proinflammatory phenotype, damage, and weakness by oxidative stress in the diaphragm muscle of mdx miceQ83435121
P4510describes a project that usesImageJQ1659584
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)R470-82
P577publication date2014-01-29
P1433published inAmerican Journal of Physiology - Regulatory, Integrative and Comparative PhysiologyQ2201819
P1476titleEUK-134 ameliorates nNOSμ translocation and skeletal muscle fiber atrophy during short-term mechanical unloading
P478volume306

Reverse relations

cites work (P2860)
Q28389514Age-related alterations in the sarcolemmal environment are attenuated by lifelong caloric restriction and voluntary exercise
Q59333111Dystrophin R16/17-syntrophin PDZ fusion protein restores sarcolemmal nNOSμ
Q57161734Effects of Iron Overload and Oxidative Damage on the Musculoskeletal System in the Space Environment: Data from Spaceflights and Ground-Based Simulation Models
Q90600489Exciting perspectives for Translational Myology in the Abstracts of the 2018Spring PaduaMuscleDays: Giovanni Salviati Memorial - Chapter II - Abstracts of March 15, 2018
Q90183929Loss of melusin is a novel, neuronal NO synthase/FoxO3-independent master switch of unloading-induced muscle atrophy
Q38883697Mitochondria in the middle: exercise preconditioning protection of striated muscle
Q89985565Molecular regulation of skeletal muscle mass and the contribution of nitric oxide: A review
Q41688477Muscle Weakness in Rheumatoid Arthritis: The Role of Ca2+ and Free Radical Signaling.
Q35834462Muscle dysfunction associated with adjuvant-induced arthritis is prevented by antioxidant treatment
Q90610950Myofibrillar function differs markedly between denervated and dexamethasone-treated rat skeletal muscles: Role of mechanical load
Q40350492Myriocin prevents muscle ceramide accumulation but not muscle fiber atrophy during short-term mechanical unloading
Q38638193No-dependent signaling pathways in unloaded skeletal muscle
Q26999716Physical exercise associated with NO production: signaling pathways and significance in health and disease
Q40454718Preservation of renal blood flow by the antioxidant EUK-134 in LPS-treated pigs
Q38748962Redox control of skeletal muscle atrophy
Q36402599Sarcolemmal targeting of nNOSμ improves contractile function of mdx muscle
Q36267615Superoxide dismutase/catalase mimetic EUK-134 prevents diaphragm muscle weakness in monocrotalin-induced pulmonary hypertension
Q37402966iTRAQ-based proteomic analysis of myofibrillar contents and relevant synthesis and proteolytic proteins in soleus muscle of hibernating Daurian ground squirrels (Spermophilus dauricus).

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