The extensive polymorphism of KIR genes

scientific article published on January 2010

The extensive polymorphism of KIR genes is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1365-2567.2009.03208.X
P932PMC publication ID2807482
P698PubMed publication ID20028428
P5875ResearchGate publication ID40758930

P2093author name stringDerek Middleton
Faviel Gonzelez
P2860cites workPlasticity in the organization and sequences of human KIR/ILT gene familiesQ24676718
IPD--the Immuno Polymorphism DatabaseQ24793789
Genomic organization of the human leukocyte immunoglobulin-like receptors within the leukocyte receptor complex on chromosome 19q13.4Q28143512
Recognition of HLA-G by the NK cell receptor KIR2DL4 is not essential for human reproductionQ28180558
Multiple copies of KIR 3DL/S1 and KIR 2DL4 genes identified in a number of individualsQ28182135
Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphismQ28201347
Allelic polymorphism synergizes with variable gene content to individualize human KIR genotypeQ28203016
KIR: diverse, rapidly evolving receptors of innate and adaptive immunityQ28203441
New allele frequency database: http://www.allelefrequencies.netQ28204761
Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cellsQ28205984
Distinctive KIR and HLA diversity in a panel of north Indian HindusQ28208283
Cutting edge: induction of IFN-gamma production but not cytotoxicity by the killer cell Ig-like receptor KIR2DL4 (CD158d) in resting NK cellsQ28211347
In search of the 'missing self': MHC molecules and NK cell recognitionQ28250846
Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donorsQ28259065
Human diversity in killer cell inhibitory receptor genesQ28259075
Investigation of killer cell immunoglobulin-like receptor gene diversity V. KIR3DL2Q28276414
Natural selection drives recurrent formation of activating killer cell immunoglobulin-like receptor and Ly49 from inhibitory homologuesQ28755874
Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C than KIR2DL3.Q29568902
Three common alleles of KIR2DL4 (CD158d) encode constitutively expressed, inducible and secreted receptors in NK cellsQ40195850
KIR3DL1 polymorphisms that affect NK cell inhibition by HLA-Bw4 ligandQ40364675
Investigation of killer cell immunoglobulin-like receptor gene diversity III. KIR2DL3.Q40537600
Investigation of killer cell immunoglobulin-like receptor gene diversity: IV. KIR3DL1/S1.Q40541366
The protein made from a common allele of KIR3DL1 (3DL1*004) is poorly expressed at cell surfaces due to substitution at positions 86 in Ig domain 0 and 182 in Ig domain 1.Q40609313
The silent KIR3DP1 gene (CD158c) is transcribed and might encode a secreted receptor in a minority of humans, in whom the KIR3DP1, KIR2DL4 and KIR3DL1/KIR3DS1 genes are duplicated.Q43746260
Receptor systems controlling natural killer cell function are genetically stratified in EuropeQ44761632
Unusual selection on the KIR3DL1/S1 natural killer cell receptor in africansQ46103159
KIR2DL5 alleles mark certain combination of activating KIR genesQ46129965
Global diversity and evidence for coevolution of KIR and HLA.Q46442901
SNP haplotypes and allele frequencies show evidence for disruptive and balancing selection in the human leukocyte receptor complexQ46950949
Cutting edge: expansion of the KIR locus by unequal crossing overQ47677728
Distinct diversity of KIR genes in three southern Indian populations: comparison with world populations revealed a link between KIR gene content and pre-historic human migrationsQ47700353
Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B.Q52842649
Low expression of inhibitory natural killer receptors in CD8 cytotoxic T lymphocytes in long-term non-progressor HIV-1-infected patientsQ58377913
High KIR diversity in Amerindians is maintained using few gene-content haplotypesQ59624570
Human NK-cell receptorsQ61719167
Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002Q73443956
The genomic organization and evolution of the natural killer immunoglobulin-like receptor (KIR) gene clusterQ73769951
Genomic diversity of natural killer cell receptor genes in three populationsQ73943144
Genotyping of human killer-cell immunoglobulin-like receptor genes by polymerase chain reaction with sequence-specific primers: an updateQ74326676
A single polymorphism disrupts the killer Ig-like receptor 2DL2/2DL3 D1 domainQ79174425
KIR haplotype content at the allele level in 77 Northern Irish familiesQ79479235
Killer immunoglobulin receptor gene and allele frequencies in Caucasoid, Oriental and Black populations from different continentsQ80172310
The reactivity of Bw4+ HLA-B and HLA-A alleles with KIR3DL1: implications for patient and donor suitability for haploidentical stem cell transplantationsQ81007095
Facilitation of KIR genotyping by a PCR-SSP method that amplifies short DNA fragmentsQ81248308
Duplication, mutation and recombination of the human orphan gene KIR2DS3 contribute to the diversity of KIR haplotypesQ81279319
Structural and functional differences between the promoters of independently expressed killer cell Ig-like receptorsQ81821260
Organization of the leukocyte receptor cluster (LRC) on human chromosome 19q13.4.Q31919135
Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemiaQ33378868
Chimpanzees use more varied receptors and ligands than humans for inhibitory killer cell Ig-like receptor recognition of the MHC-C1 and MHC-C2 epitopesQ33789518
Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humansQ33909456
Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1.Q34056087
Natural killer cell immunoglobulin-like receptor (KIR) locus profiles in African and South Asian populationsQ34124327
A common KIR2DS4 deletion variant in the human that predicts a soluble KIR molecule analogous to the KIR1D molecule observed in the rhesus monkeyQ34160230
Divergent and convergent evolution of NK-cell receptorsQ34207553
Investigation of killer cell immunoglobulin-like receptor gene diversity: II. KIR2DS4.Q34329262
The genomic context of natural killer receptor extended gene familiesQ34341455
KIR genes polymorphism in Argentinean Caucasoid and Amerindian populationsQ34627802
A bioinformatics approach to ascertaining the rarity of HLA alleles.Q35005761
Immunogenetics of killer-cell immunoglobulin-like receptorsQ35212392
Shaping the human NK cell repertoire: an epigenetic glance at KIR gene regulationQ35988380
MHC class I molecules and KIRs in human history, health and survivalQ36047157
Complex interactions: the immunogenetics of human leukocyte antigen and killer cell immunoglobulin-like receptorsQ36104562
KIR genesQ36176599
Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector functionQ36228467
The impact of variation at the KIR gene cluster on human disease.Q36331620
NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80.Q36363753
Dramatically reduced surface expression of NK cell receptor KIR2DS3 is attributed to multiple residues throughout the moleculeQ36366692
Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive successQ36399286
The Yin and Yang of HLA and KIR in human diseaseQ36410540
KIR and disease: a model system or system of models?Q36652201
Human natural killer cellsQ36787596
Killer cell immunoglobulin-like receptors on NK cells: the how, where and why.Q37037744
Role of KIRs and KIR ligands in hematopoietic transplantationQ37233484
The LRC haplotype project: a resource for killer immunoglobulin-like receptor-linked association studiesQ37324146
Natural killer cells: integrating diversity with functionQ37412618
Studies on the expression of the deleted KIR2DS4*003 gene product and distribution of KIR2DS4 deleted and nondeleted versions in different populationsQ39250115
Investigation of killer cell immunoglobulinlike receptor gene diversity: I. KIR2DL4.Q39595268
Investigation of killer cell immunoglobulin-like receptor gene diversity, KIR2DL1 and KIR2DS1.Q39958919
Killer cell immunoglobulin-like receptor allele discrimination by high-resolution melting.Q39964264
Investigation of killer cell immunoglobulin-like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5.Q39979469
P433issue1
P304page(s)8-19
P577publication date2010-01-01
P1433published inImmunologyQ15754984
P1476titleThe extensive polymorphism of KIR genes
P478volume129

Reverse relations

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